CA2604241A1 - Promoteur en vue de l'expression de genes etrangers dans des cellules neuronales - Google Patents

Promoteur en vue de l'expression de genes etrangers dans des cellules neuronales Download PDF

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Publication number
CA2604241A1
CA2604241A1 CA002604241A CA2604241A CA2604241A1 CA 2604241 A1 CA2604241 A1 CA 2604241A1 CA 002604241 A CA002604241 A CA 002604241A CA 2604241 A CA2604241 A CA 2604241A CA 2604241 A1 CA2604241 A1 CA 2604241A1
Authority
CA
Canada
Prior art keywords
sequence
gene
nucleic acid
promoter
thy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002604241A
Other languages
English (en)
Inventor
Manfred Windisch
Ulrike Bauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JSW-RESEARCH FORSCHUNGSLABOR GmbH
Original Assignee
Jsw-Research Forschungslabor Gmbh
Manfred Windisch
Ulrike Bauer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jsw-Research Forschungslabor Gmbh, Manfred Windisch, Ulrike Bauer filed Critical Jsw-Research Forschungslabor Gmbh
Publication of CA2604241A1 publication Critical patent/CA2604241A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/40—Vector systems having a special element relevant for transcription being an insulator

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002604241A 2005-04-14 2006-04-06 Promoteur en vue de l'expression de genes etrangers dans des cellules neuronales Abandoned CA2604241A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATA637/2005 2005-04-14
AT6372005A AT501628B1 (de) 2005-04-14 2005-04-14 Promotor zur expression von fremdgenen in neuronalen zellen
PCT/AT2006/000140 WO2006108201A1 (fr) 2005-04-14 2006-04-06 Promoteur en vue de l'expression de genes etrangers dans des cellules neuronales

Publications (1)

Publication Number Publication Date
CA2604241A1 true CA2604241A1 (fr) 2006-10-19

Family

ID=36608756

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002604241A Abandoned CA2604241A1 (fr) 2005-04-14 2006-04-06 Promoteur en vue de l'expression de genes etrangers dans des cellules neuronales

Country Status (5)

Country Link
EP (1) EP1869178A1 (fr)
AT (1) AT501628B1 (fr)
AU (1) AU2006235186A1 (fr)
CA (1) CA2604241A1 (fr)
WO (1) WO2006108201A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201204816D0 (en) 2012-03-19 2012-05-02 Brainco Biopharma S L Transgenic animal model of mood disorders
WO2020168111A1 (fr) 2019-02-15 2020-08-20 Exhaura, Ltd. Inhibiteurs de kinase à double glissière à leucine pour thérapie génique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610287B1 (en) * 1990-04-16 2003-08-26 The General Hospital Corporation Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
US6211428B1 (en) * 1994-09-01 2001-04-03 Merck & Co., Inc. Transgenic mouse expressing a familial form of human amyloid precursor protein
WO1998051781A1 (fr) * 1997-05-14 1998-11-19 Merck & Co., Inc. Animal transgenique exprimant une proteine preseniline 1 mutante non native de type sauvage de la maladie d'alzheimer familiale dans un contexte depourvu de preseniline 1 native
GB9924513D0 (en) * 1999-10-15 1999-12-15 Novartis Ag Organic compounds
JP2004500843A (ja) * 2000-04-24 2004-01-15 ワイエス トランスジェニック動物
CA2457317A1 (fr) * 2001-08-20 2003-02-27 Merck & Co., Inc. Rongeurs transgeniques comme modeles animaux pour la modulation de la proteine du recepteur b1 de la bradykinine
AU2003287061A1 (en) * 2002-10-11 2004-05-04 Advanced Research And Technology Institute Ferritin light subunit variant-encoding nucleic acids, polypeptides, transgenic animals, antibodies, and methods of use thereof

Also Published As

Publication number Publication date
EP1869178A1 (fr) 2007-12-26
WO2006108201A1 (fr) 2006-10-19
AT501628A1 (de) 2006-10-15
AU2006235186A1 (en) 2006-10-19
AT501628B1 (de) 2007-09-15

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Legal Events

Date Code Title Description
FZDE Discontinued