CA2602626A1 - Method of treating schizophrenia prodrome - Google Patents

Method of treating schizophrenia prodrome Download PDF

Info

Publication number
CA2602626A1
CA2602626A1 CA002602626A CA2602626A CA2602626A1 CA 2602626 A1 CA2602626 A1 CA 2602626A1 CA 002602626 A CA002602626 A CA 002602626A CA 2602626 A CA2602626 A CA 2602626A CA 2602626 A1 CA2602626 A1 CA 2602626A1
Authority
CA
Canada
Prior art keywords
glycine
optionally substituted
group
pharmaceutically acceptable
schizophrenia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002602626A
Other languages
English (en)
French (fr)
Inventor
Scott W. Woods
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2602626A1 publication Critical patent/CA2602626A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA002602626A 2005-04-11 2006-04-11 Method of treating schizophrenia prodrome Abandoned CA2602626A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67060005P 2005-04-11 2005-04-11
US60/670,600 2005-04-11
PCT/US2006/013444 WO2006110724A2 (en) 2005-04-11 2006-04-11 Method of treating schizophrenia prodrome

Publications (1)

Publication Number Publication Date
CA2602626A1 true CA2602626A1 (en) 2006-10-19

Family

ID=37087621

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002602626A Abandoned CA2602626A1 (en) 2005-04-11 2006-04-11 Method of treating schizophrenia prodrome

Country Status (7)

Country Link
US (1) US8492418B2 (ja)
EP (1) EP1871165B1 (ja)
JP (1) JP5266042B2 (ja)
AU (1) AU2006235400A1 (ja)
CA (1) CA2602626A1 (ja)
IL (1) IL186018A0 (ja)
WO (1) WO2006110724A2 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2842804B1 (fr) 2002-07-29 2004-09-03 Sanofi Synthelabo Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique
FR2861071B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-[phenyl(alkylpiperidin-2-yl) methyl]benzamide, leur prepartation et leur application en therapeutique
FR2861070B1 (fr) 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique
AU2008302225A1 (en) * 2007-09-19 2009-03-26 Bg Medicine, Inc. Methods of increasing sarcosine levels for treating schizophrenia
US20150224120A1 (en) * 2011-09-14 2015-08-13 Catherine Clelland Compositions and methods for treating hyperprolinemia-associated mental disorders
US9040581B1 (en) 2013-02-21 2015-05-26 The Florida State University Research Foundation, Inc. Methods of treatment using D-serine
EP3085690B1 (en) * 2013-12-20 2019-09-11 Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China New urea compound, manufacturing method and application thereof
CA3082834A1 (en) 2017-11-22 2019-05-31 Concert Pharmaceuticals, Inc. Deuterated analogs of d-serine and uses thereof
US11484519B2 (en) 2019-03-07 2022-11-01 Florida State University Research Foundation, Inc. D-serine inhibit neuroinflammation due to a brain injury
CN112225728A (zh) * 2020-08-18 2021-01-15 四川农业大学 一种多取代苯甲酰胺化合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355681B2 (en) * 1995-12-07 2002-03-12 Glytech, Inc. Glycine substitutes and precursors for treating a psychosis
AU2004269892B2 (en) 2003-09-09 2010-03-11 F. Hoffmann-La Roche Ag 1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses
BRPI0415833A (pt) * 2003-10-23 2007-01-02 Hoffmann La Roche derivados de triaza-espiropiperidina para uso como inibidores de glyt-1 no tratamento de distúrbios neurológicos e neuropsiquiátricos
WO2005058885A2 (en) * 2003-12-18 2005-06-30 Glaxo Group Limited Piperidine derivatives and their use as glycine transporter inhibitors
WO2005058317A1 (en) * 2003-12-18 2005-06-30 Glaxo Group Limited Glycine transporter-1 inhibirors
GB0329362D0 (en) 2003-12-18 2004-01-21 Glaxo Group Ltd Compounds
WO2005087708A1 (en) * 2004-03-12 2005-09-22 H. Lundbeck A/S Phenyl indan derivatives

Also Published As

Publication number Publication date
WO2006110724A3 (en) 2007-03-22
AU2006235400A1 (en) 2006-10-19
US8492418B2 (en) 2013-07-23
IL186018A0 (en) 2008-01-20
EP1871165A2 (en) 2008-01-02
JP5266042B2 (ja) 2013-08-21
JP2008535864A (ja) 2008-09-04
EP1871165A4 (en) 2009-10-21
US20090215842A1 (en) 2009-08-27
EP1871165B1 (en) 2017-06-21
WO2006110724A2 (en) 2006-10-19

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140131