CA2582908A1

CA2582908A1 - Inhibiteurs de liaison de domaine sh2 macrocyclique

Inhibiteurs de liaison de domaine sh2 macrocyclique Download PDF

Info

Publication number: CA2582908A1
Authority: CA; Canada
Prior art keywords: alkyl; alkoxy; aryl; compound; amino
Prior art date: 2004-09-30
Legal status : Abandoned

Application number

CA002582908A

Other languages

English (en)

Inventor

Terrence R. Burke, Jr.

Zhen-Dan Shi

Shinya Oishi

Fa Liu

Current Assignee

US Department of Health and Human Services

Original Assignee

Individual

Priority date

2004-09-30

Filing date

2005-09-30

Publication date

2006-04-13

2005-09-30 Application filed by Individual filed Critical Individual

2006-04-13 Publication of CA2582908A1 publication Critical patent/CA2582908A1/fr

Status Abandoned legal-status Critical Current

Links

239000003112 inhibitor Substances 0.000 title description 6
-1 azido, amino Chemical group 0.000 claims abstract description 100
150000001875 compounds Chemical class 0.000 claims abstract description 88
229910052739 hydrogen Inorganic materials 0.000 claims abstract description 32
238000000034 method Methods 0.000 claims abstract description 32
102000014400 SH2 domains Human genes 0.000 claims abstract description 24
108050003452 SH2 domains Proteins 0.000 claims abstract description 24
239000001257 hydrogen Substances 0.000 claims abstract description 22
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102000004169 proteins and genes Human genes 0.000 claims abstract description 21
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