CA2579292A1 - Isolated lineage negative hematopoietic stem cells and methods of treatment therewith - Google Patents

Isolated lineage negative hematopoietic stem cells and methods of treatment therewith Download PDF

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Publication number
CA2579292A1
CA2579292A1 CA002579292A CA2579292A CA2579292A1 CA 2579292 A1 CA2579292 A1 CA 2579292A1 CA 002579292 A CA002579292 A CA 002579292A CA 2579292 A CA2579292 A CA 2579292A CA 2579292 A1 CA2579292 A1 CA 2579292A1
Authority
CA
Canada
Prior art keywords
cells
hsc
hematopoietic stem
isolated
retinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002579292A
Other languages
English (en)
French (fr)
Inventor
Martin Friedlander
Atsushi Otani
Karen Da Silva
Stacey Moreno (Hanekamp)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/933,634 external-priority patent/US20050129665A1/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US2005/031304 external-priority patent/WO2006031467A2/en
Publication of CA2579292A1 publication Critical patent/CA2579292A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • C12N5/0087Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002579292A 2004-09-03 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith Abandoned CA2579292A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/933,634 US20050129665A1 (en) 2002-07-25 2004-09-03 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
US10/933,634 2004-09-03
PCT/US2005/031304 WO2006031467A2 (en) 2002-07-25 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith

Publications (1)

Publication Number Publication Date
CA2579292A1 true CA2579292A1 (en) 2006-03-23

Family

ID=37903853

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002579292A Abandoned CA2579292A1 (en) 2004-09-03 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith

Country Status (8)

Country Link
EP (1) EP1802199A4 (xx)
JP (1) JP2008512376A (xx)
KR (1) KR101309500B1 (xx)
CN (1) CN101052305B (xx)
AU (1) AU2005285246B2 (xx)
CA (1) CA2579292A1 (xx)
MX (1) MX2007002639A (xx)
ZA (1) ZA200702607B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2554662A1 (en) * 2011-08-05 2013-02-06 M Maria Pia Cosma Methods of treatment of retinal degeneration diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5928638A (en) * 1996-06-17 1999-07-27 Systemix, Inc. Methods for gene transfer
US7219016B2 (en) * 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
US6939378B2 (en) * 2001-06-01 2005-09-06 The Board Of Trustees Of The Leland Stanford Junior University Microfabricated tissue as a substrate for pigment epithelium transplantation
ES2299590T3 (es) * 2001-08-10 2008-06-01 Imclone Systems, Inc. Uso medico de celulas madre que expresan vegfr-1.ng vegfr-1.
CN1606615A (zh) * 2001-10-30 2005-04-13 第一制药株式会社 造血干细胞的增殖方法
CN1194086C (zh) * 2002-02-01 2005-03-23 北京科宇联合干细胞生物技术有限公司 一种神经干细胞制剂的制备方法
KR20110102961A (ko) * 2002-07-25 2011-09-19 더 스크립스 리서치 인스티튜트 조혈 줄기세포 및 이를 사용한 신생혈관 안구 질환의 치료방법

Also Published As

Publication number Publication date
CN101052305A (zh) 2007-10-10
AU2005285246A1 (en) 2006-03-23
EP1802199A2 (en) 2007-07-04
EP1802199A4 (en) 2008-08-27
JP2008512376A (ja) 2008-04-24
AU2005285246B2 (en) 2011-07-21
ZA200702607B (en) 2008-08-27
CN101052305B (zh) 2012-10-10
MX2007002639A (es) 2007-08-06
KR20070104512A (ko) 2007-10-26
KR101309500B1 (ko) 2013-09-24

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20170824