CA2556794A1 - Le beta-lapachone est un agent anticancereux a large spectre - Google Patents
Le beta-lapachone est un agent anticancereux a large spectre Download PDFInfo
- Publication number
- CA2556794A1 CA2556794A1 CA002556794A CA2556794A CA2556794A1 CA 2556794 A1 CA2556794 A1 CA 2556794A1 CA 002556794 A CA002556794 A CA 002556794A CA 2556794 A CA2556794 A CA 2556794A CA 2556794 A1 CA2556794 A1 CA 2556794A1
- Authority
- CA
- Canada
- Prior art keywords
- cancer
- lapachone
- pharmaceutically acceptable
- acceptable salt
- cancers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
La présente invention fournit des procédés qui utilisent des agents efficaces dans le traitement d'un large éventail d'affections cancéreuses et précancéreuses. De plus, la présente invention fournit des agents capables de servir d'inhibiteur de la prolifération de cellules sur un large éventail de types de cellules.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54591604P | 2004-02-20 | 2004-02-20 | |
US60/545,916 | 2004-02-20 | ||
PCT/US2005/005647 WO2005082358A2 (fr) | 2004-02-20 | 2005-02-18 | Le bêta-lapachone est un agent anticancereux à large spectre |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2556794A1 true CA2556794A1 (fr) | 2005-09-09 |
Family
ID=34910740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002556794A Abandoned CA2556794A1 (fr) | 2004-02-20 | 2005-02-18 | Le beta-lapachone est un agent anticancereux a large spectre |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1722776A2 (fr) |
JP (1) | JP2007523192A (fr) |
CA (1) | CA2556794A1 (fr) |
WO (1) | WO2005082358A2 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050187288A1 (en) * | 2004-02-20 | 2005-08-25 | Chiang Li | Beta-lapachone and methods of treating cancer |
CA2595564C (fr) * | 2005-02-16 | 2015-03-31 | Md Bioalpha Co., Ltd. | Composition pharmaceutique pour le traitement ou la prevention de pathologies comprenant l'obesite, le diabete, les syndromes metaboliques, les maladies neurodegeneratives, et lesmaladies liees a une dysfonction mitochondriale |
KR20090071829A (ko) * | 2007-12-28 | 2009-07-02 | 주식회사 머젠스 | 신장질환의 치료 및 예방을 위한 약제 조성물 |
WO2013153821A1 (fr) * | 2012-04-12 | 2013-10-17 | Omura Satoshi | Inhibiteur de pdk4 et son utilisation |
CN114630662A (zh) * | 2020-10-08 | 2022-06-14 | 科罗姆生物科技有限公司 | 包含β-拉帕醌作为有效成分的用于预防或治疗胆汁淤积性肝病的药学组合物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5763625A (en) * | 1995-04-25 | 1998-06-09 | Wisconsin Alumni Research Foundation | Synthesis and use of β-lapachone analogs |
US5883270A (en) * | 1996-02-20 | 1999-03-16 | Wisconsin Alumni Research Foundation | 4-substituted-1, 2-naphthoquinones and their use in the inhibition of neoplastic cell growth |
AU2003254029A1 (en) * | 2002-07-17 | 2004-02-02 | Arqule, Inc. | Activated checkpoint therapy and methods of use thereof |
TW200510367A (en) * | 2002-11-18 | 2005-03-16 | Arqule Inc | Novel lapachone compounds, their preparation, and the use thereof |
EP1575580A4 (fr) * | 2002-12-02 | 2009-06-10 | Arqule Inc | Methodes de traitement de cancers |
-
2005
- 2005-02-18 JP JP2006554304A patent/JP2007523192A/ja not_active Withdrawn
- 2005-02-18 CA CA002556794A patent/CA2556794A1/fr not_active Abandoned
- 2005-02-18 EP EP05723508A patent/EP1722776A2/fr not_active Ceased
- 2005-02-18 WO PCT/US2005/005647 patent/WO2005082358A2/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2005082358A2 (fr) | 2005-09-09 |
EP1722776A2 (fr) | 2006-11-22 |
JP2007523192A (ja) | 2007-08-16 |
WO2005082358A3 (fr) | 2005-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20091229 |