CA2543305A1 - Ache antisense deoxyoligonucleotide as an anti-inflammatory agent - Google Patents
Ache antisense deoxyoligonucleotide as an anti-inflammatory agent Download PDFInfo
- Publication number
- CA2543305A1 CA2543305A1 CA002543305A CA2543305A CA2543305A1 CA 2543305 A1 CA2543305 A1 CA 2543305A1 CA 002543305 A CA002543305 A CA 002543305A CA 2543305 A CA2543305 A CA 2543305A CA 2543305 A1 CA2543305 A1 CA 2543305A1
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- Prior art keywords
- ache
- inhibitor
- expression
- seq
- antisense oligonucleotide
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL158600A IL158600A (en) | 2003-10-26 | 2003-10-26 | Dioxysoligonucleotide Antisense Against Acetylcholinesterase as an Anti-Inflammatory Agent |
| IL158600 | 2003-10-26 | ||
| PCT/IL2004/000978 WO2005039480A2 (en) | 2003-10-26 | 2004-10-26 | AChE ANTISENSE DEOXYOLIGONUCLEOTIDE AS AN ANTI-INFLAMMATORY AGENT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2543305A1 true CA2543305A1 (en) | 2005-05-06 |
Family
ID=34044237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002543305A Abandoned CA2543305A1 (en) | 2003-10-26 | 2004-10-26 | Ache antisense deoxyoligonucleotide as an anti-inflammatory agent |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20060069051A1 (enExample) |
| EP (2) | EP1682072A4 (enExample) |
| JP (1) | JP4753088B2 (enExample) |
| CA (1) | CA2543305A1 (enExample) |
| IL (1) | IL158600A (enExample) |
| WO (1) | WO2005039480A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2007399A2 (en) * | 2006-04-10 | 2008-12-31 | Ester Neurosciences Ltd. | Antisense oligonucleotides against acetylcholinesterase for treating inflammatory diseases |
| US20110136897A1 (en) * | 2008-08-14 | 2011-06-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Toll-like receptor 9 agonists for the treatment of anxiety-related disorders and inflammatory disorders |
| MX2011011517A (es) | 2009-04-29 | 2012-06-19 | Amarin Corp Plc | Composiciones farmaceuticas que comprenden epa y un agente cardiovascular y metodos para utilizar el mismo. |
| CN102458109B (zh) | 2009-04-29 | 2015-02-11 | 阿马里纳制药公司 | 稳定的药物组合物和使用其的方法 |
| US9814733B2 (en) | 2012-12-31 | 2017-11-14 | A,arin Pharmaceuticals Ireland Limited | Compositions comprising EPA and obeticholic acid and methods of use thereof |
| US9283201B2 (en) | 2013-03-14 | 2016-03-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating or preventing obesity in a subject in need thereof |
| US20220102008A1 (en) * | 2020-09-30 | 2022-03-31 | Genentech, Inc. | Methods and systems for placebo response modeling |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL101600A (en) * | 1992-04-15 | 2000-02-29 | Yissum Res Dev Co | Synthetic partially phosphorothioated antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
| US6495579B1 (en) * | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| AU727611B2 (en) * | 1996-12-12 | 2000-12-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
| AU8742198A (en) * | 1997-08-15 | 1999-03-08 | Shire International Licensing B.V. | Use of cholinesterase inhibitor for treating diseases associated with pro teolytic enzyme activity |
| IL143379A (en) | 2001-05-24 | 2013-11-28 | Yissum Res Dev Co | Oligonucleotide against human ache isoform r and its uses |
| EP2007399A2 (en) * | 2006-04-10 | 2008-12-31 | Ester Neurosciences Ltd. | Antisense oligonucleotides against acetylcholinesterase for treating inflammatory diseases |
-
2003
- 2003-10-26 IL IL158600A patent/IL158600A/en not_active IP Right Cessation
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2004
- 2004-10-26 EP EP04791840A patent/EP1682072A4/en not_active Withdrawn
- 2004-10-26 CA CA002543305A patent/CA2543305A1/en not_active Abandoned
- 2004-10-26 WO PCT/IL2004/000978 patent/WO2005039480A2/en not_active Ceased
- 2004-10-26 EP EP13153748.2A patent/EP2599489A1/en not_active Withdrawn
- 2004-10-26 JP JP2006537550A patent/JP4753088B2/ja not_active Expired - Fee Related
-
2005
- 2005-07-21 US US11/187,719 patent/US20060069051A1/en not_active Abandoned
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2007
- 2007-04-18 US US11/788,321 patent/US20090005331A1/en not_active Abandoned
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2013
- 2013-05-22 US US13/899,922 patent/US8722876B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL158600A0 (en) | 2004-05-12 |
| WO2005039480A3 (en) | 2006-08-03 |
| WO2005039480A8 (en) | 2006-06-15 |
| EP1682072A4 (en) | 2010-10-13 |
| IL158600A (en) | 2015-07-30 |
| US20130310441A1 (en) | 2013-11-21 |
| JP2007509186A (ja) | 2007-04-12 |
| EP1682072A2 (en) | 2006-07-26 |
| US20060069051A1 (en) | 2006-03-30 |
| US20090005331A1 (en) | 2009-01-01 |
| US8722876B2 (en) | 2014-05-13 |
| JP4753088B2 (ja) | 2011-08-17 |
| WO2005039480A2 (en) | 2005-05-06 |
| EP2599489A1 (en) | 2013-06-05 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20130522 |