CA2536016C - Polymeres de glycosaminoglycane cibles par greffage de polymeres et leurs procedes de fabrication et d'utilisation - Google Patents

Polymeres de glycosaminoglycane cibles par greffage de polymeres et leurs procedes de fabrication et d'utilisation Download PDF

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Publication number
CA2536016C
CA2536016C CA2536016A CA2536016A CA2536016C CA 2536016 C CA2536016 C CA 2536016C CA 2536016 A CA2536016 A CA 2536016A CA 2536016 A CA2536016 A CA 2536016A CA 2536016 C CA2536016 C CA 2536016C
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Canada
Prior art keywords
udp
pmhas
sugar
polymers
chondroitin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2536016A
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English (en)
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CA2536016A1 (fr
Inventor
Paul L. Deangelis
Wei Jing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Oklahoma
Original Assignee
University of Oklahoma
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Publication date
Application filed by University of Oklahoma filed Critical University of Oklahoma
Priority claimed from PCT/US2003/025750 external-priority patent/WO2004032830A2/fr
Publication of CA2536016A1 publication Critical patent/CA2536016A1/fr
Application granted granted Critical
Publication of CA2536016C publication Critical patent/CA2536016C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

L'invention concerne la méthodologie du greffage de polymères par une polysaccharide synthase et, plus précisément, du greffage de polymères faisant appel à la hyaluronate, la chondroïtine ou l'héparine/héparosan synthases issue de la pasteurella, afin de créer une variété d'oligosaccharides de glycosaminoglycane possédant une structure de sucre naturelle, chimère ou hybride d'une taille ciblée, qui sont sensiblement monodispersés en taille.
CA2536016A 2002-08-16 2003-08-14 Polymeres de glycosaminoglycane cibles par greffage de polymeres et leurs procedes de fabrication et d'utilisation Expired - Fee Related CA2536016C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US40435602P 2002-08-16 2002-08-16
US60/404,356 2002-08-16
US47943203P 2003-06-18 2003-06-18
US60/479,432 2003-06-18
US49136203P 2003-07-31 2003-07-31
US60/491,362 2003-07-31
PCT/US2003/025750 WO2004032830A2 (fr) 2002-08-16 2003-08-14 Polymeres de glycosaminoglycane cibles par greffage de polymeres et leurs procedes de fabrication et d'utilisation

Publications (2)

Publication Number Publication Date
CA2536016A1 CA2536016A1 (fr) 2004-04-22
CA2536016C true CA2536016C (fr) 2017-01-10

Family

ID=32096021

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2536016A Expired - Fee Related CA2536016C (fr) 2002-08-16 2003-08-14 Polymeres de glycosaminoglycane cibles par greffage de polymeres et leurs procedes de fabrication et d'utilisation

Country Status (2)

Country Link
EP (1) EP1575622A2 (fr)
CA (1) CA2536016C (fr)

Also Published As

Publication number Publication date
EP1575622A2 (fr) 2005-09-21
CA2536016A1 (fr) 2004-04-22

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20180814