CA2535908A1 - Manifold assembly - Google Patents

Manifold assembly Download PDF

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Publication number
CA2535908A1
CA2535908A1 CA 2535908 CA2535908A CA2535908A1 CA 2535908 A1 CA2535908 A1 CA 2535908A1 CA 2535908 CA2535908 CA 2535908 CA 2535908 A CA2535908 A CA 2535908A CA 2535908 A1 CA2535908 A1 CA 2535908A1
Authority
CA
Canada
Prior art keywords
manifold
fluid
manifold assembly
assembly
bottle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2535908
Other languages
French (fr)
Other versions
CA2535908C (en
Inventor
Xuan S. Bui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sakura Finetek USA Inc
Original Assignee
Sakura Finetek USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/349,325 external-priority patent/US7744817B2/en
Application filed by Sakura Finetek USA Inc filed Critical Sakura Finetek USA Inc
Publication of CA2535908A1 publication Critical patent/CA2535908A1/en
Application granted granted Critical
Publication of CA2535908C publication Critical patent/CA2535908C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

A manifold assembly that directs fluid to and from individually selectable sample receiving trays of a tissue processing system includes a manifold, fluid conduits machined in the manifold, and valves that may be selectively configured to provide a direct fluid path to or from a particular tray. The valves are controlled by a controller that positions each valve such that a desired path is created. Pressure is created in supply and/or drain bottles to supply or drain fluid from the trays supported by the manifold assembly. Independently operated heaters are provided on the manifold assembly to heat the trays to desired temperatures. Thermoelectric cooling elements may also provided to cool the heaters and/or trays.

Claims (24)

1. A manifold assembly for an automated tissue processing system comprising:
a manifold including a pattern of fluid conduits extending therethrough; and a platen attached to the manifold, the platen including a plurality of sample receiving portions, wherein each sample receiving portion includes an inlet in fluid communication with at least one fluid conduit of the manifold and an outlet in fluid communication with at least one fluid conduit.
2. The manifold assembly of claim 1 wherein the manifold is formed from two separate pieces of material.
3. The manifold assembly of claim 2 wherein the two separate pieces of material are mechanically etched to form complementing passageways and coupled such that the complementing passageways form the pattern of fluid conduits.
4. The manifold assembly of claim 2 wherein the material is a polymer.
5. The manifold assembly of claim 2 wherein the two pieces of material are mechanically fastened together.
6. The manifold assembly of claim 1 wherein the manifold is in fluid communication with at least one supply bottle and at least one waste bottle.
7. The manifold assembly of claim 6 further comprising a pressure pump in fluid communication with the at least one supply bottle.
8. The manifold assembly of claim 6 further comprising a vacuum pump in fluid communication with the at least one waste bottle.
9. The manifold assembly of claim 1 further comprising an inlet port on a proximal end of the platen and an evacuation port on a distal end of the platen.
10. The manifold assembly of claim 1 further comprising a plurality of valves configured to control fluid flow through the fluid conduits.
11. The manifold assembly of claim 10 further comprising a valve controller coupled to the manifold.
12. The manifold assembly of claim 11 further comprising a drip frame coupled to the manifold between the manifold and the controller.
13. The manifold assembly of claim 6 wherein the at least one supply bottle includes a fluid level sensor.
14. The manifold assembly of claim 13 wherein the at least one waste bottle includes a fluid level sensor.
15. The manifold assembly of claim 14 wherein the fluid level sensors are coupled to a common sensor carrier.
16. The manifold assembly of claim 15 wherein the sensor carrier is configured to translate parallel to a vertical axis of the supply bottle.
17. The manifold assembly of claim 1 further comprising at least one heater coupled to at least one of the sample receiving portions.
18. The manifold assembly of claim 1 further comprising a plurality of heaters coupled to the platen wherein each of the plurality of heaters is independently operated.
19. A method of operating a manifold of an automated tissue processor comprising:
receiving instructions regarding a program to process;

positioning a plurality of valves included in a manifold assembly supporting a tissue sample to create a fluid path between a supply source and an inlet of a sample receiving tray, wherein the manifold assembly includes a manifold that defines a plurality of fluid paths extending therethrough; and applying a reagent to a tissue sample through the fluid path and the inlet of the sample receiving tray.
20. A manifold system for use in a tissue processing system, comprising:
a manifold assembly;
a plurality of bulk fluid bottles in fluid communication with the manifold assembly;
a plurality of fluid level sensors, each fluid level sensor being disposed adjacent to a respective bulk fluid bottle;
a sensor carrier that is configured to be translated in a direction parallel to a vertical axis of the supply bottle, wherein the plurality of fluid level sensors is coupled to the sensor carrier.
21. The manifold system of claim 20 further comprising a pressure pump including a pressurized fluid output that is fluidly coupled to at least one bulk fluid bottle.
22. The manifold system of claim 21 further comprising a vacuum pump including a fluid input that is fluidly coupled to at least one bulk fluid bottle.
23. The manifold system of claim 20, wherein the manifold assembly includes a manifold including a pattern of fluid conduits extending therethrough.
24. The manifold system of claim 23, wherein the manifold is formed from two separate pieces of material.
CA002535908A 2005-02-11 2006-02-09 Manifold assembly Active CA2535908C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65244005P 2005-02-11 2005-02-11
US60/652,440 2005-02-11
US11/349,325 US7744817B2 (en) 2003-08-11 2006-02-06 Manifold assembly
US11/349,325 2006-02-06

Publications (2)

Publication Number Publication Date
CA2535908A1 true CA2535908A1 (en) 2006-08-11
CA2535908C CA2535908C (en) 2009-12-08

Family

ID=36791508

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002535908A Active CA2535908C (en) 2005-02-11 2006-02-09 Manifold assembly

Country Status (2)

Country Link
CN (1) CN1818605A (en)
CA (1) CA2535908C (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102374941B (en) * 2010-08-16 2013-06-19 江苏赛达医疗科技有限公司 Liquid flow switching device without fluid retention
CN106165557B (en) * 2014-12-08 2018-10-26 约翰逊控制技术公司 A kind of variable speed drive system and a kind of cooling system for closing heat generating electronic devices in the housing
JP6629996B2 (en) * 2016-05-23 2020-01-15 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company Liquid dispenser with modular independently activated multiple pipette channels
CN114903024A (en) * 2022-06-20 2022-08-16 北京中科原动力科技有限公司 Automatic pesticide spraying system, plant protection robot and automatic pesticide spraying control method

Also Published As

Publication number Publication date
CN1818605A (en) 2006-08-16
CA2535908C (en) 2009-12-08

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