CA2530646C - Methode specifique de detection du cancer de la prostate sur la base du gene pca3 et trousses associees - Google Patents
Methode specifique de detection du cancer de la prostate sur la base du gene pca3 et trousses associees Download PDFInfo
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- CA2530646C CA2530646C CA2530646A CA2530646A CA2530646C CA 2530646 C CA2530646 C CA 2530646C CA 2530646 A CA2530646 A CA 2530646A CA 2530646 A CA2530646 A CA 2530646A CA 2530646 C CA2530646 C CA 2530646C
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Abstract
D'une manière générale, l'invention concerne le cancer de la prostate. D'une manière plus spécifique, l'invention concerne une méthode permettant de diagnostiquer un cancer de la prostate chez un patient en détectant une séquence PCA3 et plus particulièrement un ARN PCA3, la séquence PCA3 détectée dans un échantillon prélevé sur le patient étant spécifiquement associée au cancer de la prostate. Dans un mode de réalisation particulier, la méthode et la trousse permettent d'amplifier un ARN PCA3 via une jonction exon-exon d'un ARNm PCA3 épissé. L'invention concerne également des méthodes et des trousses permettant de détecter un ARN PCA3 ainsi amplifié au moyen d'une sonde qui couvre la jonction exon-exon amplifiée. L'invention concerne en outre des trousses contenant des amorces d'acide nucléique et des trousses contenant des amorces d'acide nucléique et des sondes d'acide nucléique afin de diagnostiquer, d'évaluer ou de pronostiquer un cancer de la prostate chez être humain. Les méthodes et trousses selon l'invention sont spécialement conçues pour détecter un ARN PCA3 auquel il manque au moins un intron, lequel ARN est, dans ce cas particulier, dépourvu d'introns.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2530646A CA2530646C (fr) | 2003-06-30 | 2004-06-30 | Methode specifique de detection du cancer de la prostate sur la base du gene pca3 et trousses associees |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002432365A CA2432365A1 (fr) | 2003-06-30 | 2003-06-30 | Methode specifique de detection du cancer de la prostate fondee sur le gene pca3 et trousses connexes |
| CA2,432,365 | 2003-06-30 | ||
| CA2530646A CA2530646C (fr) | 2003-06-30 | 2004-06-30 | Methode specifique de detection du cancer de la prostate sur la base du gene pca3 et trousses associees |
| PCT/EP2004/007124 WO2005003387A2 (fr) | 2003-06-30 | 2004-06-30 | Methode specifique de detection du cancer de la prostate sur la base du gene pca3 et trousses associees |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2530646A1 CA2530646A1 (fr) | 2005-01-13 |
| CA2530646C true CA2530646C (fr) | 2015-11-03 |
Family
ID=36141764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2530646A Expired - Lifetime CA2530646C (fr) | 2003-06-30 | 2004-06-30 | Methode specifique de detection du cancer de la prostate sur la base du gene pca3 et trousses associees |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2530646C (fr) |
-
2004
- 2004-06-30 CA CA2530646A patent/CA2530646C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2530646A1 (fr) | 2005-01-13 |
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