CA2519128A1 - Apparatus and method for ascertaining cardiac output and other parameters - Google Patents
Apparatus and method for ascertaining cardiac output and other parameters Download PDFInfo
- Publication number
- CA2519128A1 CA2519128A1 CA002519128A CA2519128A CA2519128A1 CA 2519128 A1 CA2519128 A1 CA 2519128A1 CA 002519128 A CA002519128 A CA 002519128A CA 2519128 A CA2519128 A CA 2519128A CA 2519128 A1 CA2519128 A1 CA 2519128A1
- Authority
- CA
- Canada
- Prior art keywords
- cannula
- patient
- sensor assembly
- probe
- forearm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000000747 cardiac effect Effects 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims description 13
- 239000000523 sample Substances 0.000 claims abstract description 80
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 45
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 45
- 239000001301 oxygen Substances 0.000 claims abstract description 45
- 239000008280 blood Substances 0.000 claims abstract description 35
- 210000004369 blood Anatomy 0.000 claims abstract description 35
- 210000000245 forearm Anatomy 0.000 claims abstract description 31
- 210000003462 vein Anatomy 0.000 claims abstract description 20
- 210000001367 artery Anatomy 0.000 claims abstract description 17
- 210000001147 pulmonary artery Anatomy 0.000 claims abstract description 9
- 238000001727 in vivo Methods 0.000 claims abstract description 7
- 239000004020 conductor Substances 0.000 claims description 36
- 239000007853 buffer solution Substances 0.000 claims description 25
- 210000003414 extremity Anatomy 0.000 claims description 19
- 238000005259 measurement Methods 0.000 claims description 11
- 238000003780 insertion Methods 0.000 claims description 8
- 230000037431 insertion Effects 0.000 claims description 8
- 239000012528 membrane Substances 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 3
- 229920003023 plastic Polymers 0.000 claims description 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical class [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 37
- 229910052697 platinum Inorganic materials 0.000 description 17
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 12
- 239000004332 silver Substances 0.000 description 11
- 229910052709 silver Inorganic materials 0.000 description 11
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 10
- 238000009413 insulation Methods 0.000 description 9
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 8
- 229910021607 Silver chloride Inorganic materials 0.000 description 8
- 239000011248 coating agent Substances 0.000 description 8
- 238000000576 coating method Methods 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 8
- 229920001296 polysiloxane Polymers 0.000 description 7
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 description 6
- 239000011521 glass Substances 0.000 description 6
- 239000001569 carbon dioxide Substances 0.000 description 5
- 239000007789 gas Substances 0.000 description 4
- 235000011164 potassium chloride Nutrition 0.000 description 4
- 239000001103 potassium chloride Substances 0.000 description 4
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 239000004809 Teflon Substances 0.000 description 3
- 229920006362 Teflon® Polymers 0.000 description 3
- 230000002965 anti-thrombogenic effect Effects 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000003550 marker Substances 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 238000001361 intraarterial administration Methods 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000004447 silicone coating Substances 0.000 description 2
- 150000003378 silver Chemical class 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 208000029549 Muscle injury Diseases 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 101100272073 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) AVO2 gene Proteins 0.000 description 1
- 230000003126 arrythmogenic effect Effects 0.000 description 1
- 230000008321 arterial blood flow Effects 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000002302 brachial artery Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003527 fibrinolytic agent Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- MUMZUERVLWJKNR-UHFFFAOYSA-N oxoplatinum Chemical compound [Pt]=O MUMZUERVLWJKNR-UHFFFAOYSA-N 0.000 description 1
- 150000002926 oxygen Chemical class 0.000 description 1
- 238000001139 pH measurement Methods 0.000 description 1
- 230000036581 peripheral resistance Effects 0.000 description 1
- 229910003446 platinum oxide Inorganic materials 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
- A61B5/029—Measuring blood output from the heart, e.g. minute volume
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
- A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
- A61B5/028—Measuring blood flow using tracers, e.g. dye dilution by thermo-dilution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6848—Needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
- A61B2562/0215—Silver or silver chloride containing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Optics & Photonics (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/956,064 US6616614B2 (en) | 2001-09-18 | 2001-09-18 | Apparatus and method for ascertaining cardiac output and other parameters |
| PCT/US2003/008043 WO2004082475A1 (en) | 2001-09-18 | 2003-03-14 | Apparatus and method for ascertaining cardiac output and other parameters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2519128A1 true CA2519128A1 (en) | 2004-09-30 |
Family
ID=33479090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002519128A Abandoned CA2519128A1 (en) | 2001-09-18 | 2003-03-14 | Apparatus and method for ascertaining cardiac output and other parameters |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6616614B2 (enExample) |
| EP (1) | EP1608264A4 (enExample) |
| JP (1) | JP4369873B2 (enExample) |
| AU (1) | AU2003225823B2 (enExample) |
| CA (1) | CA2519128A1 (enExample) |
| WO (1) | WO2004082475A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6616614B2 (en) * | 2001-09-18 | 2003-09-09 | Keimar Corporation | Apparatus and method for ascertaining cardiac output and other parameters |
| US7630747B2 (en) * | 2003-09-09 | 2009-12-08 | Keimar, Inc. | Apparatus for ascertaining blood characteristics and probe for use therewith |
| GB0324450D0 (en) * | 2003-10-20 | 2003-11-19 | Alertis Medical As | Sensor |
| JP2008512162A (ja) * | 2004-09-08 | 2008-04-24 | アラーティス メディカル エイエス | センサ |
| CA2563851A1 (en) * | 2005-10-19 | 2007-04-19 | Animas Corporation | Flexible metallic cannula infusion set |
| US20070167865A1 (en) * | 2005-11-29 | 2007-07-19 | Lopez George A | Cardiac output measurement devices and methods |
| WO2007093981A2 (en) * | 2006-02-15 | 2007-08-23 | Medingo Ltd. | Systems and methods for sensing analyte and dispensing therapeutic fluid |
| US20070265564A1 (en) * | 2006-05-15 | 2007-11-15 | Medtronic Vascular, Inc. | Catheter Having Non-Blood-Contacting Exit Markers |
| US7643879B2 (en) | 2006-08-24 | 2010-01-05 | Cardiac Pacemakers, Inc. | Integrated cardiac rhythm management system with heart valve |
| US20080183235A1 (en) * | 2007-01-31 | 2008-07-31 | Stancer Christopher C | Insulative shroud for plate-type electrodes adapted for chronic implantation |
| US20080249388A1 (en) * | 2007-04-06 | 2008-10-09 | Thinkvillage, Llc | Systems and methods for cooling of intravenous fluid and monitoring of in vivo characteristics |
| EP2244631A4 (en) * | 2008-01-15 | 2014-01-22 | Nicholas L Taro | METHOD AND APPARATUS FOR DETERMINING DETERIORATION OF RESPIRATORY FUNCTION |
| US20100010328A1 (en) * | 2008-07-11 | 2010-01-14 | Nguyen Harry D | Probes and sensors for ascertaining blood characteristics and methods and devices for use therewith |
| US20100057046A1 (en) * | 2008-09-03 | 2010-03-04 | Keimar, Inc | Systems for characterizing physiologic parameters and methods for use therewith |
| JP2009207924A (ja) * | 2009-06-23 | 2009-09-17 | Keimar Inc | 心拍出量を把握するための装置及び方法 |
| EP3838139B1 (en) * | 2016-12-05 | 2024-01-03 | Medipines Corporation | Device for respiratory measurements using breathing gas samples |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH564771A5 (enExample) * | 1973-05-10 | 1975-07-31 | Hoffmann La Roche | |
| AU484366B2 (en) * | 1975-03-10 | 1975-07-03 | Oximetrix, Inc | Catheter apparatus |
| US4015600A (en) * | 1975-07-07 | 1977-04-05 | Liautaud James P | Catheter needle assembly |
| US4221567A (en) * | 1977-12-23 | 1980-09-09 | Intermountain Health Care | Sampling and determination of diffusible chemical substances |
| DE3700119A1 (de) * | 1987-01-03 | 1988-07-14 | Inst Diabetestechnologie Gemei | Implantierbarer elektrochemischer sensor |
| US4874500A (en) | 1987-07-15 | 1989-10-17 | Sri International | Microelectrochemical sensor and sensor array |
| US4819655A (en) * | 1987-08-04 | 1989-04-11 | Webler William E | Injectateless thermal cardiac output determination method and apparatus |
| US5409666A (en) * | 1991-08-08 | 1995-04-25 | Minnesota Mining And Manufacturing Company | Sensors and methods for sensing |
| US5322063A (en) * | 1991-10-04 | 1994-06-21 | Eli Lilly And Company | Hydrophilic polyurethane membranes for electrochemical glucose sensors |
| JPH07508183A (ja) * | 1992-02-01 | 1995-09-14 | ザ ヴィクトリア ユニヴァーシティ オヴ マンチェスター | モニタリングシステムに関する改良 |
| US5354448A (en) * | 1992-05-22 | 1994-10-11 | Biomedical Sensors Ltd. | Electrochemical sensor |
| US5651767A (en) * | 1994-05-06 | 1997-07-29 | Alfred F. Mann Foundation For Scientific Research | Replaceable catheter system for physiological sensors, stimulating electrodes and/or implantable fluid delivery systems |
| US5971934A (en) * | 1996-10-04 | 1999-10-26 | Trustees Of The University Of Pennsylvania | Noninvasive method and apparatus for determining cardiac output |
| US5788647A (en) * | 1997-01-24 | 1998-08-04 | Eggers; Philip E. | Method, system and apparatus for evaluating hemodynamic parameters |
| US5928155A (en) * | 1997-01-24 | 1999-07-27 | Cardiox Corporation | Cardiac output measurement with metabolizable analyte containing fluid |
| US5944695A (en) * | 1997-09-30 | 1999-08-31 | Becton, Dickinson And Company | Multiple sheath catheter using multiple stages and method of use |
| CA2388033A1 (en) * | 1999-10-07 | 2001-04-12 | Alexander K. Mills | Device and method for noninvasive continuous determination of physiologic characteristics |
| US6616614B2 (en) * | 2001-09-18 | 2003-09-09 | Keimar Corporation | Apparatus and method for ascertaining cardiac output and other parameters |
-
2001
- 2001-09-18 US US09/956,064 patent/US6616614B2/en not_active Expired - Fee Related
-
2003
- 2003-03-14 JP JP2004569650A patent/JP4369873B2/ja not_active Expired - Fee Related
- 2003-03-14 EP EP03816387A patent/EP1608264A4/en not_active Withdrawn
- 2003-03-14 WO PCT/US2003/008043 patent/WO2004082475A1/en not_active Ceased
- 2003-03-14 CA CA002519128A patent/CA2519128A1/en not_active Abandoned
- 2003-03-14 AU AU2003225823A patent/AU2003225823B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006513786A (ja) | 2006-04-27 |
| JP4369873B2 (ja) | 2009-11-25 |
| EP1608264A1 (en) | 2005-12-28 |
| US20030055353A1 (en) | 2003-03-20 |
| WO2004082475A1 (en) | 2004-09-30 |
| US6616614B2 (en) | 2003-09-09 |
| EP1608264A4 (en) | 2010-04-07 |
| AU2003225823B2 (en) | 2009-08-27 |
| AU2003225823A1 (en) | 2004-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6616614B2 (en) | Apparatus and method for ascertaining cardiac output and other parameters | |
| US7630747B2 (en) | Apparatus for ascertaining blood characteristics and probe for use therewith | |
| US20100010328A1 (en) | Probes and sensors for ascertaining blood characteristics and methods and devices for use therewith | |
| EP1148808B1 (en) | Holter-type monitor system comprising an analyte sensor | |
| US5660163A (en) | Glucose sensor assembly | |
| US5791344A (en) | Patient monitoring system | |
| US9072476B2 (en) | Flexible sensor apparatus | |
| US20100057046A1 (en) | Systems for characterizing physiologic parameters and methods for use therewith | |
| US20110184258A1 (en) | Balloon Catheter Analyte Measurement Sensors and Methods for Using the Same | |
| US20100204605A1 (en) | Physiological parameter sensors | |
| Gottrup et al. | Continuous direct tissue oxygen tension measurement by a new method using an implantable silastic tonometer and oxygen polarography | |
| JP2006513786A5 (enExample) | ||
| Venkatesh et al. | Continuous measurement of blood gases using a combined electrochemical and spectrophotometric sensor | |
| JP2009207924A (ja) | 心拍出量を把握するための装置及び方法 | |
| HK1113735B (en) | Apparatus for ascertaining blood characteristics and probe for use therewith |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20121127 |