CA2516286A1 - Expression dans des plantes d'anticorps contre l'<i>escherichia coli </i>entero-toxigene - Google Patents

Expression dans des plantes d'anticorps contre l'<i>escherichia coli </i>entero-toxigene Download PDF

Info

Publication number
CA2516286A1
CA2516286A1 CA002516286A CA2516286A CA2516286A1 CA 2516286 A1 CA2516286 A1 CA 2516286A1 CA 002516286 A CA002516286 A CA 002516286A CA 2516286 A CA2516286 A CA 2516286A CA 2516286 A1 CA2516286 A1 CA 2516286A1
Authority
CA
Canada
Prior art keywords
antibody
plant
domain
sequence
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002516286A
Other languages
English (en)
Inventor
Devon Brown
Manuel Campos
Bipin Dalmia
Stephen Demarest
Genevieve Hansen
Peter Bernard Heifetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2516286A1 publication Critical patent/CA2516286A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/13Immunoglobulins specific features characterized by their source of isolation or production isolated from plants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002516286A 2003-02-18 2004-02-16 Expression dans des plantes d'anticorps contre l'<i>escherichia coli </i>entero-toxigene Abandoned CA2516286A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44842903P 2003-02-18 2003-02-18
US60/448,429 2003-02-18
PCT/EP2004/001427 WO2004074491A2 (fr) 2003-02-18 2004-02-16 Expression dans des plantes d'anticorps contre l'escherichia coli entero-toxigene

Publications (1)

Publication Number Publication Date
CA2516286A1 true CA2516286A1 (fr) 2004-09-02

Family

ID=32908588

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002516286A Abandoned CA2516286A1 (fr) 2003-02-18 2004-02-16 Expression dans des plantes d'anticorps contre l'<i>escherichia coli </i>entero-toxigene

Country Status (5)

Country Link
EP (1) EP1597372A2 (fr)
CN (1) CN1761754A (fr)
AU (1) AU2004213554A1 (fr)
CA (1) CA2516286A1 (fr)
WO (1) WO2004074491A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1749839A1 (fr) * 2005-07-22 2007-02-07 Novoplant GmbH Polypeptides de liaison d'antigènes F4 (K88) fimbriae
ES2387023T3 (es) * 2006-04-21 2012-09-11 Amgen Inc. Dominios de región constante de inmunoglobulina con estabilidad mejorada
JP5616449B2 (ja) * 2010-07-20 2014-10-29 国立大学法人 東京大学 ナノ抗体を発現するトランスジェニックイネ
WO2014033313A1 (fr) 2012-09-03 2014-03-06 Vib Vzw Anticorps protégeant contre l'etec
CN107686518B (zh) * 2016-08-05 2019-12-06 中国农业大学 一种抗大肠杆菌k88ac的单链抗体及其编码基因与应用
EP4172181A4 (fr) * 2020-06-26 2024-07-17 Univ Massachusetts Anticorps de protéine adhésine anti-etec et procédés d'utilisation
CN112094340B (zh) * 2020-07-31 2023-06-20 王跃驹 植物作为宿主在表达新型冠状病毒肺炎中和抗体b38抗体和/或h4抗体中的应用
WO2024047558A2 (fr) * 2022-08-31 2024-03-07 Immuneel Therapeutics Private Limited Protéines de liaison à l'antigène et récepteurs antigéniques chimériques spécifiques pour le domaine 9 de cd307e humain

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1330718A (zh) * 1998-10-07 2002-01-09 辛根塔参与股份公司 植物中的治疗活性蛋白质

Also Published As

Publication number Publication date
WO2004074491A2 (fr) 2004-09-02
WO2004074491A3 (fr) 2004-11-18
AU2004213554A2 (en) 2004-09-02
AU2004213554A1 (en) 2004-09-02
EP1597372A2 (fr) 2005-11-23
CN1761754A (zh) 2006-04-19

Similar Documents

Publication Publication Date Title
JP2000510340A (ja) 集合分泌抗体を発現するトランスジェニック植物
US9080180B2 (en) Transgenic plants expressing STX2EB protein for use as a pig edema disease vaccine
US6852319B2 (en) Method of use of transgenic plant expressed antibodies
US10829546B2 (en) Protective anti-ETEC antibody
CA2839932A1 (fr) De-glycosylation in vivo de proteines recombinees par co-expression avec la pngase f
CA2440358C (fr) Proteines oligomeres semblables a une chaperone, stables face aux denaturants et/ou resistant a la protease, polynucleotides codant les memes proteines et utilisations correspondantes
CA2516286A1 (fr) Expression dans des plantes d&#39;anticorps contre l&#39;&lt;i&gt;escherichia coli &lt;/i&gt;entero-toxigene
Chen et al. Expression of engineered antibodies in plants: a possible tool for spiroplasma and phytoplasma disease control
US7253341B2 (en) Denaturant stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same, their uses and methods of increasing a specific activity thereof
Sasou et al. Development of Antibody-Fragment–Producing Rice for Neutralization of Human Norovirus
US20110061136A1 (en) Fusion protein that directs vaccine antigens to antigen-presenting cells, and applications thereof
US20060172298A1 (en) Denaturat stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same, their uses and methods of increasing a specific activity thereof
Malembic et al. Effect of polyclonal, monoclonal, and recombinant (single-chain variable fragment) antibodies on in vitro morphology, growth, and metabolism of the phytopathogenic mollicute Spiroplasma citri
CA2592894C (fr) Qualite de grain ameliore par l&#39;expression modifiee de la proteine gamma-zein
US20050138692A1 (en) Production of cancer-specific antibodies in plants
Hajibehzad et al. High-level transient expression of the N-terminal domain of IpaD from Shigella dysenteriae in four plant species transformed with different construct configurations
Palací Bataller Evaluation of plant produced novel vaccines and camelid derived immunoglobulins against post-weaning diarrhea in piglets
Yiu et al. Transgenic rice expresses an antigenic lipoprotein of Neisseria gonorrhoeae
Virdi Oral passive immunisation of weaned piglets against F4-positive enterotoxigenic Escherichia coli by in seed produced antibodies
WO2013152624A1 (fr) Gène synthétique résistant au glyphosate et son utilisation

Legal Events

Date Code Title Description
FZDE Discontinued