CA2506027A1 - Imidazopyridines substituees en position 8 - Google Patents

Imidazopyridines substituees en position 8 Download PDF

Info

Publication number
CA2506027A1
CA2506027A1 CA002506027A CA2506027A CA2506027A1 CA 2506027 A1 CA2506027 A1 CA 2506027A1 CA 002506027 A CA002506027 A CA 002506027A CA 2506027 A CA2506027 A CA 2506027A CA 2506027 A1 CA2506027 A1 CA 2506027A1
Authority
CA
Canada
Prior art keywords
alkoxy
alkyl
hydrogen
hydroxy
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002506027A
Other languages
English (en)
Inventor
Wilm Buhr
Joerg Senn-Bilfinger
Peter Jan Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2506027A1 publication Critical patent/CA2506027A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention a trait à des imidazopyridines substituées en position 8, représentées par la formule (I), dont les substituants et les symboles sont tels que définis dans le descriptif de l'invention. Lesdits composés possèdent des propriétés inhibitrices de la sécrétion gastrique et d'excellentes propriétés protectrices de l'estomac et de l'intestin.
CA002506027A 2002-11-19 2003-11-15 Imidazopyridines substituees en position 8 Abandoned CA2506027A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02025866 2002-11-19
EP02025866.1 2002-11-19
PCT/EP2003/012787 WO2004046144A1 (fr) 2002-11-19 2003-11-15 Imidazopyridines substituees en position 8

Publications (1)

Publication Number Publication Date
CA2506027A1 true CA2506027A1 (fr) 2004-06-03

Family

ID=32319543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002506027A Abandoned CA2506027A1 (fr) 2002-11-19 2003-11-15 Imidazopyridines substituees en position 8

Country Status (17)

Country Link
US (1) US7326718B2 (fr)
EP (1) EP1565465A1 (fr)
JP (1) JP2006508142A (fr)
KR (1) KR20050086584A (fr)
CN (1) CN100384842C (fr)
AU (1) AU2003288071A1 (fr)
BR (1) BR0316201A (fr)
CA (1) CA2506027A1 (fr)
EA (1) EA008304B1 (fr)
HR (1) HRP20050528A2 (fr)
MX (1) MXPA05005117A (fr)
NO (1) NO20052857L (fr)
NZ (1) NZ540504A (fr)
PL (1) PL375567A1 (fr)
RS (1) RS20050377A (fr)
WO (1) WO2004046144A1 (fr)
ZA (1) ZA200503224B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101913531B1 (ko) * 2004-07-28 2018-10-30 다케다 야쿠힌 고교 가부시키가이샤 피롤로〔2,3-ｃ〕피리딘 화합물, 그 제조 방법 및 용도
AP2007004023A0 (en) * 2004-12-17 2007-06-30 Pfizer Chromane derivatives useful as acid pump antagonists
US20080255358A1 (en) * 2005-03-24 2008-10-16 Mark James Bamford Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
WO2007026218A2 (fr) * 2005-09-01 2007-03-08 Pfizer Japan Inc. Derives de 2-alkyl imidazopyridine a substitution chromane
EP1934215A1 (fr) * 2005-09-22 2008-06-25 Nycomed GmbH Dérivés de l'imidazopyridine porteurs de substitutions par des isotopes pour le traitement de troubles gastro-intestinaux
MX2008011044A (es) * 2006-03-17 2008-10-09 Raqualia Pharma Inc Derivados de cromano.
WO2008071766A2 (fr) * 2006-12-14 2008-06-19 Nycomed Gmbh Dérivés d'imidazopyridine substitués par spiro, pharmaceutiquement actifs
US8648080B2 (en) 2009-07-09 2014-02-11 Raqualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86269A0 (en) * 1987-05-08 1988-11-15 Byk Gulden Lomberg Chem Fab Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
CA1327796C (fr) 1987-07-16 1994-03-15 Jorg Senn-Bilfinger Diazoles
EP0368158A1 (fr) * 1988-11-07 1990-05-16 Byk Gulden Lomberg Chemische Fabrik GmbH Imidazopyridines
WO1998042707A1 (fr) 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Composes de tetrahydropyrido
ID22718A (id) 1997-03-24 1999-12-09 Byk Gulden Lomberg Chem Fab Senyawa-senyawa tetrahidropirido
CN1257505A (zh) 1997-05-28 2000-06-21 比克·古尔顿·劳姆贝尔格化学公司 稠合的二氢吡喃类化合物
SE9801526D0 (sv) 1998-04-29 1998-04-29 Astra Ab New compounds
CZ292335B6 (cs) 1998-09-23 2003-09-17 Altana Pharma Ag Tetrahydropyridoethery, jejich použití a farmaceutický prostředek
CA2349476A1 (fr) 1998-11-03 2000-05-11 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazonaphtyridines
DE60002855T2 (de) 1999-04-17 2004-05-06 Altana Pharma Ag Haloalkoxy-imidazonaphthyridine
MXPA02009551A (es) 2000-03-29 2004-05-14 Altana Pharma Ag Profarmacos de derivados de imidazopiridina.
CA2404460A1 (fr) 2000-03-29 2001-10-04 Altana Pharma Ag Derives imidazopyridine alkyles
KR20020082494A (ko) 2000-03-29 2002-10-31 알타나 파마 아게 위장 질환 치료용피라노[2,3-씨]이미다조[1,2-에이]피리딘 유도체
CA2404477A1 (fr) 2000-03-29 2001-10-04 Altana Pharma Ag Imidazopyridines tricycliques
SE0100297D0 (sv) 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) 2001-02-01 2001-02-01 Astrazeneca Ab New compounds

Also Published As

Publication number Publication date
EP1565465A1 (fr) 2005-08-24
KR20050086584A (ko) 2005-08-30
WO2004046144A1 (fr) 2004-06-03
HRP20050528A2 (en) 2006-06-30
CN1708497A (zh) 2005-12-14
PL375567A1 (en) 2005-11-28
CN100384842C (zh) 2008-04-30
WO2004046144A8 (fr) 2007-03-22
US7326718B2 (en) 2008-02-05
US20060100234A1 (en) 2006-05-11
NO20052857L (no) 2005-06-13
AU2003288071A1 (en) 2004-06-15
NZ540504A (en) 2007-12-21
ZA200503224B (en) 2005-11-22
EA200500711A1 (ru) 2005-12-29
JP2006508142A (ja) 2006-03-09
MXPA05005117A (es) 2005-07-01
EA008304B1 (ru) 2007-04-27
RS20050377A (en) 2007-11-15
BR0316201A (pt) 2005-10-04

Similar Documents

Publication Publication Date Title
EP1173439B1 (fr) Haloalcoxy-imidazonaphtyridines
US20030158193A1 (en) Alkylated imidazopyridine derivatives
EP1313740B1 (fr) Promedicaments de derives d'imidazopyridine
US20080113962A1 (en) Condensed Tricyclic Benzimidazoles For the Treatment of Gastrointestinal Disorders
ZA200400918B (en) Tricyclic imidazopyridines.
ZA200503224B (en) 8-Substituted imidazopyridines.
EP1758900B1 (fr) Benzimidazoles tricycliques substitues
WO2006100254A1 (fr) Benzimidazoles 6-substitués par des groupements thioamide
WO2006061380A2 (fr) Imidazo[4,5-b]pyridines substitues
WO2005058893A1 (fr) Benzimidazoles tricycliques
AU2005293576A1 (en) Difluoro-substituted imidazopyridines
AU2005212855A1 (en) Tricyclic imidazopyridines and intermediates for the synthesis thereof

Legal Events

Date Code Title Description
FZDE Discontinued