CA2499058A1 - Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total - Google Patents
Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total Download PDFInfo
- Publication number
- CA2499058A1 CA2499058A1 CA002499058A CA2499058A CA2499058A1 CA 2499058 A1 CA2499058 A1 CA 2499058A1 CA 002499058 A CA002499058 A CA 002499058A CA 2499058 A CA2499058 A CA 2499058A CA 2499058 A1 CA2499058 A1 CA 2499058A1
- Authority
- CA
- Canada
- Prior art keywords
- ldl
- cholesterol
- sample
- ldl cholesterol
- test strip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
- G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention a trait à une bande d'essai en phase sèche (20) et à un procédé permettant de déterminer la concentration du cholestérol LDL dans un échantillon de sang total ou de plasma. La bande d'essai (20) selon l'invention comprend un empilement (92) ou une feuille, qui mesure la concentration du cholestérol total, et un autre empilement (94) ou feuille, qui mesure la concentration du cholestérol <= non LDL >=, soit la somme du cholestérol HDL, du cholestérol VLDL, et des chylomicrons. La différence entre les valeurs obtenues correspond à la concentration de cholestérol LDL. Les bandes d'essai en phase sèche (20) selon l'invention fonctionnent à température ambiante, et tous les résultats de l'essai sont produits à partir de mesures du facteur de réflexion effectuées lors d'un pseudo-point de virage, si bien qu'il n'est pas nécessaire de chronométrer le procédé d'essai. L'invention se rapporte également à la production d'une feuille à lipides améliorée, qui indique la concentration, dans un échantillon sanguin, du cholestérol HDL, du cholestérol total et du cholestérol LDL, et ce sans faire appel à la formule de Friedewald.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41120902P | 2002-09-16 | 2002-09-16 | |
US60/411,209 | 2002-09-16 | ||
PCT/US2003/029102 WO2004025265A2 (fr) | 2002-09-16 | 2003-09-16 | Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2499058A1 true CA2499058A1 (fr) | 2004-03-25 |
Family
ID=31994248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002499058A Abandoned CA2499058A1 (fr) | 2002-09-16 | 2003-09-16 | Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1540353A4 (fr) |
AU (1) | AU2003272453A1 (fr) |
CA (1) | CA2499058A1 (fr) |
MX (1) | MXPA05002955A (fr) |
WO (1) | WO2004025265A2 (fr) |
ZA (1) | ZA200502214B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10204606C1 (de) | 2002-01-18 | 2003-10-16 | Cholestech Corp | Vorrichtung und Verfahren für Lipoproteine hoher Dichte |
ES2252358T3 (es) | 2002-04-09 | 2006-05-16 | Cholestech Corporation | Metodo y dispositivo de ensayo para la cuantificacion del colesterol asociado a lipoproteinas de alta densidad. |
US7772007B2 (en) | 2004-04-02 | 2010-08-10 | Cholestech Corporation | Assay device for direct measurement of LDL cholesterol |
WO2008086019A1 (fr) * | 2007-01-09 | 2008-07-17 | Cholestech Corporation | Dispositif et procédé de mesure du cholestérol associé au ldl |
CN101657546B (zh) | 2007-09-05 | 2013-01-02 | 爱科来株式会社 | 低密度脂蛋白(ldl)胆固醇测定方法以及ldl胆固醇测定用试验片 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5132086A (en) * | 1990-02-06 | 1992-07-21 | Chemtrak Corporation | Non-instrumented cholesterol assay |
US5135716A (en) * | 1989-07-12 | 1992-08-04 | Kingston Diagnostics, L.P. | Direct measurement of HDL cholesterol via dry chemistry strips |
US5460974A (en) * | 1992-10-13 | 1995-10-24 | Miles Inc. | Method of assaying whole blood for HDL cholesterol |
JP3193634B2 (ja) * | 1996-05-29 | 2001-07-30 | 第一化学薬品株式会社 | Ldlコレステロールの定量方法 |
JP3441993B2 (ja) * | 1999-01-27 | 2003-09-02 | 松下電器産業株式会社 | コレステロールセンサ |
US6524864B2 (en) * | 2000-12-28 | 2003-02-25 | Aurora L. Fernandez Decastro | Test strip for simultaneous detection of a plurality of analytes |
-
2003
- 2003-09-16 WO PCT/US2003/029102 patent/WO2004025265A2/fr not_active Application Discontinuation
- 2003-09-16 AU AU2003272453A patent/AU2003272453A1/en not_active Abandoned
- 2003-09-16 CA CA002499058A patent/CA2499058A1/fr not_active Abandoned
- 2003-09-16 EP EP03754634A patent/EP1540353A4/fr not_active Withdrawn
- 2003-09-16 MX MXPA05002955A patent/MXPA05002955A/es not_active Application Discontinuation
-
2005
- 2005-03-16 ZA ZA200502214A patent/ZA200502214B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2004025265A2 (fr) | 2004-03-25 |
MXPA05002955A (es) | 2005-10-18 |
AU2003272453A1 (en) | 2004-04-30 |
ZA200502214B (en) | 2006-05-31 |
EP1540353A2 (fr) | 2005-06-15 |
WO2004025265A3 (fr) | 2004-07-01 |
EP1540353A4 (fr) | 2007-01-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |