CA2499058A1 - Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total - Google Patents

Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total Download PDF

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Publication number
CA2499058A1
CA2499058A1 CA002499058A CA2499058A CA2499058A1 CA 2499058 A1 CA2499058 A1 CA 2499058A1 CA 002499058 A CA002499058 A CA 002499058A CA 2499058 A CA2499058 A CA 2499058A CA 2499058 A1 CA2499058 A1 CA 2499058A1
Authority
CA
Canada
Prior art keywords
ldl
cholesterol
sample
ldl cholesterol
test strip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002499058A
Other languages
English (en)
Inventor
Bruce Shull
Hyeon-Sook Lee Zeng
Sunil Anaokar
Gena Lynn Antonopoulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Polymer Technology Systems Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2499058A1 publication Critical patent/CA2499058A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention a trait à une bande d'essai en phase sèche (20) et à un procédé permettant de déterminer la concentration du cholestérol LDL dans un échantillon de sang total ou de plasma. La bande d'essai (20) selon l'invention comprend un empilement (92) ou une feuille, qui mesure la concentration du cholestérol total, et un autre empilement (94) ou feuille, qui mesure la concentration du cholestérol <= non LDL >=, soit la somme du cholestérol HDL, du cholestérol VLDL, et des chylomicrons. La différence entre les valeurs obtenues correspond à la concentration de cholestérol LDL. Les bandes d'essai en phase sèche (20) selon l'invention fonctionnent à température ambiante, et tous les résultats de l'essai sont produits à partir de mesures du facteur de réflexion effectuées lors d'un pseudo-point de virage, si bien qu'il n'est pas nécessaire de chronométrer le procédé d'essai. L'invention se rapporte également à la production d'une feuille à lipides améliorée, qui indique la concentration, dans un échantillon sanguin, du cholestérol HDL, du cholestérol total et du cholestérol LDL, et ce sans faire appel à la formule de Friedewald.
CA002499058A 2002-09-16 2003-09-16 Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total Abandoned CA2499058A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41120902P 2002-09-16 2002-09-16
US60/411,209 2002-09-16
PCT/US2003/029102 WO2004025265A2 (fr) 2002-09-16 2003-09-16 Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total

Publications (1)

Publication Number Publication Date
CA2499058A1 true CA2499058A1 (fr) 2004-03-25

Family

ID=31994248

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002499058A Abandoned CA2499058A1 (fr) 2002-09-16 2003-09-16 Bande d'essai et procede permettant de determiner la concentration du cholesterol ldl a partir d'un echantillon de sang total

Country Status (6)

Country Link
EP (1) EP1540353A4 (fr)
AU (1) AU2003272453A1 (fr)
CA (1) CA2499058A1 (fr)
MX (1) MXPA05002955A (fr)
WO (1) WO2004025265A2 (fr)
ZA (1) ZA200502214B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10204606C1 (de) 2002-01-18 2003-10-16 Cholestech Corp Vorrichtung und Verfahren für Lipoproteine hoher Dichte
ES2252358T3 (es) 2002-04-09 2006-05-16 Cholestech Corporation Metodo y dispositivo de ensayo para la cuantificacion del colesterol asociado a lipoproteinas de alta densidad.
US7772007B2 (en) 2004-04-02 2010-08-10 Cholestech Corporation Assay device for direct measurement of LDL cholesterol
WO2008086019A1 (fr) * 2007-01-09 2008-07-17 Cholestech Corporation Dispositif et procédé de mesure du cholestérol associé au ldl
CN101657546B (zh) 2007-09-05 2013-01-02 爱科来株式会社 低密度脂蛋白（ldl）胆固醇测定方法以及ldl胆固醇测定用试验片

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132086A (en) * 1990-02-06 1992-07-21 Chemtrak Corporation Non-instrumented cholesterol assay
US5135716A (en) * 1989-07-12 1992-08-04 Kingston Diagnostics, L.P. Direct measurement of HDL cholesterol via dry chemistry strips
US5460974A (en) * 1992-10-13 1995-10-24 Miles Inc. Method of assaying whole blood for HDL cholesterol
JP3193634B2 (ja) * 1996-05-29 2001-07-30 第一化学薬品株式会社 Ｌｄｌコレステロールの定量方法
JP3441993B2 (ja) * 1999-01-27 2003-09-02 松下電器産業株式会社 コレステロールセンサ
US6524864B2 (en) * 2000-12-28 2003-02-25 Aurora L. Fernandez Decastro Test strip for simultaneous detection of a plurality of analytes

Also Published As

Publication number Publication date
WO2004025265A2 (fr) 2004-03-25
MXPA05002955A (es) 2005-10-18
AU2003272453A1 (en) 2004-04-30
ZA200502214B (en) 2006-05-31
EP1540353A2 (fr) 2005-06-15
WO2004025265A3 (fr) 2004-07-01
EP1540353A4 (fr) 2007-01-24

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued