CA2492528C - Method and apparatus for predicting work of breathing - Google Patents
Method and apparatus for predicting work of breathing Download PDFInfo
- Publication number
- CA2492528C CA2492528C CA2492528A CA2492528A CA2492528C CA 2492528 C CA2492528 C CA 2492528C CA 2492528 A CA2492528 A CA 2492528A CA 2492528 A CA2492528 A CA 2492528A CA 2492528 C CA2492528 C CA 2492528C
- Authority
- CA
- Canada
- Prior art keywords
- breathing
- respiratory
- pressure
- patient
- data
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000029058 respiratory gaseous exchange Effects 0.000 title claims abstract description 129
- 238000000034 method Methods 0.000 title claims abstract description 67
- 238000013178 mathematical model Methods 0.000 claims abstract description 31
- 230000000241 respiratory effect Effects 0.000 claims description 77
- 238000013528 artificial neural network Methods 0.000 claims description 49
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 46
- 230000003434 inspiratory effect Effects 0.000 claims description 36
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 25
- 239000001569 carbon dioxide Substances 0.000 claims description 23
- 238000012545 processing Methods 0.000 claims description 18
- 238000012549 training Methods 0.000 claims description 13
- 230000035565 breathing frequency Effects 0.000 claims description 12
- 230000000977 initiatory effect Effects 0.000 claims description 9
- 210000000779 thoracic wall Anatomy 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 3
- 238000003062 neural network model Methods 0.000 claims description 3
- 238000010200 validation analysis Methods 0.000 claims 8
- 230000003519 ventilatory effect Effects 0.000 abstract description 12
- 230000003044 adaptive effect Effects 0.000 abstract description 3
- 238000004364 calculation method Methods 0.000 abstract description 2
- 238000009423 ventilation Methods 0.000 description 16
- 210000004072 lung Anatomy 0.000 description 7
- 210000003019 respiratory muscle Anatomy 0.000 description 7
- 210000002345 respiratory system Anatomy 0.000 description 7
- 239000000047 product Substances 0.000 description 6
- 230000002269 spontaneous effect Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- 238000005259 measurement Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000004422 calculation algorithm Methods 0.000 description 3
- 238000004590 computer program Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000005399 mechanical ventilation Methods 0.000 description 3
- 206010049565 Muscle fatigue Diseases 0.000 description 2
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000001010 compromised effect Effects 0.000 description 2
- 238000005094 computer simulation Methods 0.000 description 2
- 238000013480 data collection Methods 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000003238 esophagus Anatomy 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 230000007310 pathophysiology Effects 0.000 description 2
- 210000004224 pleura Anatomy 0.000 description 2
- 210000003281 pleural cavity Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 201000004193 respiratory failure Diseases 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 206010061688 Barotrauma Diseases 0.000 description 1
- 206010021079 Hypopnoea Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 238000013529 biological neural network Methods 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
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- 230000001939 inductive effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 108700025647 major vault Proteins 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
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- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
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- 230000009467 reduction Effects 0.000 description 1
- 238000009531 respiratory rate measurement Methods 0.000 description 1
- 238000002644 respiratory therapy Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
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- 230000001960 triggered effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
- A61B5/036—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs by means introduced into body tracts
- A61B5/037—Measuring oesophageal pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/085—Measuring impedance of respiratory organs or lung elasticity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
- A61M16/026—Control means therefor including calculation means, e.g. using a processor specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0036—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the breathing tube and used in both inspiratory and expiratory phase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40709902P | 2002-08-30 | 2002-08-30 | |
| US60/407,099 | 2002-08-30 | ||
| PCT/US2003/027297 WO2004019766A2 (en) | 2002-08-30 | 2003-08-29 | Method and apparatus for predicting work of breathing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2492528A1 CA2492528A1 (en) | 2004-03-11 |
| CA2492528C true CA2492528C (en) | 2014-03-18 |
Family
ID=31978419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2492528A Expired - Lifetime CA2492528C (en) | 2002-08-30 | 2003-08-29 | Method and apparatus for predicting work of breathing |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7425201B2 (https=) |
| EP (2) | EP2377463B1 (https=) |
| JP (1) | JP4836453B2 (https=) |
| AU (1) | AU2003268324B2 (https=) |
| BR (2) | BRPI0313823B8 (https=) |
| CA (1) | CA2492528C (https=) |
| WO (1) | WO2004019766A2 (https=) |
Families Citing this family (134)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5915380A (en) | 1997-03-14 | 1999-06-29 | Nellcor Puritan Bennett Incorporated | System and method for controlling the start up of a patient ventilator |
| US20070000494A1 (en) * | 1999-06-30 | 2007-01-04 | Banner Michael J | Ventilator monitor system and method of using same |
| US20080200775A1 (en) * | 2007-02-20 | 2008-08-21 | Lynn Lawrence A | Maneuver-based plethysmographic pulse variation detection system and method |
| EP1596704B1 (en) * | 2003-01-30 | 2019-08-07 | Compumedics Medical Innovation Pty Ltd | Algorithm for automatic positive air pressure titration |
| DE10337138A1 (de) * | 2003-08-11 | 2005-03-17 | Freitag, Lutz, Dr. | Verfahren und Anordnung zur Atmungsunterstützung eines Patienten sowie Luftröhrenprothese und Katheter |
| US7588033B2 (en) | 2003-06-18 | 2009-09-15 | Breathe Technologies, Inc. | Methods, systems and devices for improving ventilation in a lung area |
| AU2004266693B2 (en) | 2003-08-18 | 2011-03-10 | Breathe Technologies, Inc | Method and device for non-invasive ventilation with nasal interface |
| CN100544670C (zh) * | 2004-02-18 | 2009-09-30 | 马奎特紧急护理公司 | 使用肌电活动来优化病人的呼吸辅助的设备 |
| ES2557324T3 (es) * | 2004-02-23 | 2016-01-25 | Sss Acquisition, Llc | Alimentos que contienen ácidos de lúpulo y su utilización como suplementos en piensos |
| SE0401208D0 (sv) * | 2004-05-10 | 2004-05-10 | Breas Medical Ab | Multilevel ventilator |
| WO2006037184A1 (en) * | 2004-10-06 | 2006-04-13 | Resmed Limited | Method and apparatus for non-invasive monitoring of respiratory parameters in sleep disordered breathing |
| US7903090B2 (en) * | 2005-06-10 | 2011-03-08 | Qsi Corporation | Force-based input device |
| US7337085B2 (en) | 2005-06-10 | 2008-02-26 | Qsi Corporation | Sensor baseline compensation in a force-based touch device |
| US20080170043A1 (en) * | 2005-06-10 | 2008-07-17 | Soss David A | Force-based input device |
| US20060284856A1 (en) * | 2005-06-10 | 2006-12-21 | Soss David A | Sensor signal conditioning in a force-based touch device |
| US7487774B2 (en) * | 2005-08-05 | 2009-02-10 | The General Electric Company | Adaptive patient trigger threshold detection |
| CN101454041B (zh) * | 2005-09-20 | 2012-12-12 | 呼吸科技公司 | 对患者进行呼吸支持的系统、方法和装置 |
| US8172766B1 (en) | 2005-11-04 | 2012-05-08 | Cleveland Medical Devices Inc. | Integrated sleep diagnosis and treatment device and method |
| US8545416B1 (en) | 2005-11-04 | 2013-10-01 | Cleveland Medical Devices Inc. | Integrated diagnostic and therapeutic system and method for improving treatment of subject with complex and central sleep apnea |
| JP5264506B2 (ja) | 2006-01-19 | 2013-08-14 | マケット・クリティカル・ケア・アーベー | 機械的な呼吸補助を受ける自発呼吸患者の呼吸特性を動的に決定するデバイス |
| US8021310B2 (en) | 2006-04-21 | 2011-09-20 | Nellcor Puritan Bennett Llc | Work of breathing display for a ventilation system |
| CN101541365A (zh) * | 2006-05-18 | 2009-09-23 | 呼吸科技公司 | 气管切开方法和装置 |
| US7861710B2 (en) * | 2006-06-30 | 2011-01-04 | Aeris Therapeutics, Inc. | Respiratory assistance apparatus and method |
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| US9533113B2 (en) | 2007-01-04 | 2017-01-03 | Oridion Medical 1987 Ltd. | Integrated pulmonary index for weaning from mechanical ventilation |
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| CN101380233B (zh) | 2007-09-05 | 2010-12-22 | 深圳迈瑞生物医疗电子股份有限公司 | 基于呼吸力学模块的呼吸功实时监测方法及监测装置 |
| JP5519510B2 (ja) | 2007-09-26 | 2014-06-11 | ブリーズ・テクノロジーズ・インコーポレーテッド | 換気装置 |
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| CN101461719B (zh) | 2007-12-18 | 2012-02-01 | 深圳迈瑞生物医疗电子股份有限公司 | 一种多普勒扫描变换实现方法和装置 |
| CN101938939B (zh) * | 2008-02-07 | 2014-11-26 | 皇家飞利浦电子股份有限公司 | 用于测量和预测患者呼吸稳定性的装置 |
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- 2003-08-29 EP EP11173288.9A patent/EP2377463B1/en not_active Expired - Lifetime
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- 2003-08-29 US US10/652,992 patent/US7425201B2/en not_active Expired - Lifetime
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| BRPI0313823B1 (pt) | 2020-03-10 |
| US20070232951A1 (en) | 2007-10-04 |
| AU2003268324B2 (en) | 2008-05-29 |
| JP2005537068A (ja) | 2005-12-08 |
| US7425201B2 (en) | 2008-09-16 |
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