CA2491056A1 - Benzoate- and anthranilate-inducible promoters - Google Patents
Benzoate- and anthranilate-inducible promoters Download PDFInfo
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- CA2491056A1 CA2491056A1 CA002491056A CA2491056A CA2491056A1 CA 2491056 A1 CA2491056 A1 CA 2491056A1 CA 002491056 A CA002491056 A CA 002491056A CA 2491056 A CA2491056 A CA 2491056A CA 2491056 A1 CA2491056 A1 CA 2491056A1
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- Prior art keywords
- promoter
- seq
- polynucleotide
- sequence
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- UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 description 1
- 239000011654 magnesium acetate Substances 0.000 description 1
- 235000011285 magnesium acetate Nutrition 0.000 description 1
- 229940069446 magnesium acetate Drugs 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical class [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- UODXCYZDMHPIJE-UHFFFAOYSA-N menthanol Chemical compound CC1CCC(C(C)(C)O)CC1 UODXCYZDMHPIJE-UHFFFAOYSA-N 0.000 description 1
- 108010068488 methionylphenylalanine Proteins 0.000 description 1
- 238000010369 molecular cloning Methods 0.000 description 1
- 239000003068 molecular probe Substances 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 229910017464 nitrogen compound Inorganic materials 0.000 description 1
- 108091027963 non-coding RNA Proteins 0.000 description 1
- 102000042567 non-coding RNA Human genes 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 238000001821 nucleic acid purification Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 150000002896 organic halogen compounds Chemical class 0.000 description 1
- 150000004028 organic sulfates Chemical class 0.000 description 1
- 150000002898 organic sulfur compounds Chemical class 0.000 description 1
- 150000002902 organometallic compounds Chemical class 0.000 description 1
- 150000002903 organophosphorus compounds Chemical class 0.000 description 1
- 150000003961 organosilicon compounds Chemical class 0.000 description 1
- 230000002018 overexpression Effects 0.000 description 1
- 150000004893 oxazines Chemical class 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 108010087558 pectate lyase Proteins 0.000 description 1
- 150000002988 phenazines Chemical class 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229940049953 phenylacetate Drugs 0.000 description 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 description 1
- 108010073025 phenylalanylphenylalanine Proteins 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000008301 phosphite esters Chemical class 0.000 description 1
- 102000020233 phosphotransferase Human genes 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 210000002706 plastid Anatomy 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 230000008488 polyadenylation Effects 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 235000011056 potassium acetate Nutrition 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 108010077112 prolyl-proline Proteins 0.000 description 1
- 108010015796 prolylisoleucine Proteins 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 101150068263 putA gene Proteins 0.000 description 1
- 101150057603 putP gene Proteins 0.000 description 1
- 150000003230 pyrimidines Chemical class 0.000 description 1
- 150000003248 quinolines Chemical class 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000037425 regulation of transcription Effects 0.000 description 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 108091092562 ribozyme Proteins 0.000 description 1
- 239000007320 rich medium Substances 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 150000003873 salicylate salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 108010048818 seryl-histidine Proteins 0.000 description 1
- 108010071207 serylmethionine Proteins 0.000 description 1
- 239000013605 shuttle vector Substances 0.000 description 1
- 239000004055 small Interfering RNA Substances 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- FRGKKTITADJNOE-UHFFFAOYSA-N sulfanyloxyethane Chemical compound CCOS FRGKKTITADJNOE-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical class [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- KUUVQVSHGLHAKZ-UHFFFAOYSA-N thionine Chemical compound C=1C=CC=CSC=CC=1 KUUVQVSHGLHAKZ-UHFFFAOYSA-N 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
- 150000003628 tricarboxylic acids Chemical class 0.000 description 1
- 108700004896 tripeptide FEG Proteins 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
- PIEPQKCYPFFYMG-UHFFFAOYSA-N tris acetate Chemical compound CC(O)=O.OCC(N)(CO)CO PIEPQKCYPFFYMG-UHFFFAOYSA-N 0.000 description 1
- 108010029384 tryptophyl-histidine Proteins 0.000 description 1
- 108010084932 tryptophyl-proline Proteins 0.000 description 1
- 108010051110 tyrosyl-lysine Proteins 0.000 description 1
- 108010078580 tyrosylleucine Proteins 0.000 description 1
- 108010003137 tyrosyltyrosine Proteins 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
- YSGSDAIMSCVPHG-UHFFFAOYSA-N valyl-methionine Chemical compound CSCCC(C(O)=O)NC(=O)C(N)C(C)C YSGSDAIMSCVPHG-UHFFFAOYSA-N 0.000 description 1
- 108010021889 valylvaline Proteins 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 108010027345 wheylin-1 peptide Proteins 0.000 description 1
- 150000003732 xanthenes Chemical class 0.000 description 1
- 150000003738 xylenes Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39342202P | 2002-07-03 | 2002-07-03 | |
| US60/393,422 | 2002-07-03 | ||
| PCT/US2003/020840 WO2004005221A2 (en) | 2002-07-03 | 2003-07-03 | Benzoate- and anthranilate-inducible promoters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2491056A1 true CA2491056A1 (en) | 2004-01-15 |
Family
ID=30115575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002491056A Abandoned CA2491056A1 (en) | 2002-07-03 | 2003-07-03 | Benzoate- and anthranilate-inducible promoters |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7794972B2 (enExample) |
| EP (1) | EP1539794B1 (enExample) |
| JP (1) | JP2006506049A (enExample) |
| CN (1) | CN1678624B (enExample) |
| AT (1) | ATE419265T1 (enExample) |
| AU (1) | AU2003256365B2 (enExample) |
| CA (1) | CA2491056A1 (enExample) |
| DE (1) | DE60325611D1 (enExample) |
| WO (1) | WO2004005221A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| US7985564B2 (en) | 2003-11-21 | 2011-07-26 | Pfenex, Inc. | Expression systems with sec-system secretion |
| EP2434016B1 (en) | 2004-01-16 | 2018-11-07 | Pfenex Inc. | Expression of mammalian proteins in pseudomonas fluorescens |
| EP3388521A1 (en) | 2004-02-27 | 2018-10-17 | Dow AgroSciences LLC | High efficiency peptide production in plant cells |
| US8603824B2 (en) | 2004-07-26 | 2013-12-10 | Pfenex, Inc. | Process for improved protein expression by strain engineering |
| JP5167813B2 (ja) | 2005-05-12 | 2013-03-21 | 味の素株式会社 | タンパク質の製造法 |
| CN102517280A (zh) | 2007-01-31 | 2012-06-27 | 菲尼克斯股份有限公司 | 用于提高表达的细菌前导序列 |
| CA2964910C (en) | 2007-04-27 | 2018-01-09 | Pfenex Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| EP2185716B1 (en) * | 2007-08-08 | 2013-01-16 | Wayne M. Barnes | Improved t7 expression system |
| US8318481B2 (en) | 2007-12-07 | 2012-11-27 | Pfenex Inc. | High copy number self-replicating plasmids in pseudomonas |
| DE102008052529A1 (de) * | 2008-10-21 | 2010-04-22 | Henkel Ag & Co. Kgaa | Expressionsverstärkte Nukleinsäuren |
| AU2010247938B2 (en) | 2009-05-11 | 2016-02-18 | Pelican Technology Holdings, Inc. | Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein |
| CN104379729B (zh) | 2012-07-03 | 2020-07-21 | 花王株式会社 | 有用微生物和目标物质的制备方法 |
| DK2880168T3 (en) * | 2012-08-05 | 2017-04-18 | Absci Llc | INDUCERABLE CO EXPRESSION SYSTEM |
| EP3158065B1 (en) | 2014-06-18 | 2019-01-09 | Calysta, Inc. | Nucleic acids and vectors for use with methanotrophic bacteria |
| CN113444183B (zh) | 2014-12-01 | 2025-06-17 | 佩利肯科技控股公司 | 用于肽生产的融合伴侣 |
| CN120736973A (zh) | 2017-10-26 | 2025-10-03 | 诺鲁Ic有限公司 | 3-羟基丙酸的生产与分离 |
| US11566250B2 (en) | 2017-10-26 | 2023-01-31 | Noroo Ic Co., Ltd. | Production and separation of 3-hydroxypropionic acid |
| CN109486847B (zh) * | 2018-12-17 | 2021-03-02 | 江南大学 | 基于人工串联启动子的枯草芽孢杆菌高效诱导表达系统 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6415739A (en) | 1987-07-09 | 1989-01-19 | Konishiroku Photo Ind | Processing of silver halide color photographic sensitive material |
| US5593860A (en) | 1987-08-14 | 1997-01-14 | Bio-Technology General Corp. | Expression plasmids containing the deo promoter, and bacterial hosts containing the plasmids |
| JPH0284195A (ja) | 1988-05-31 | 1990-03-26 | Mitsubishi Kasei Corp | 天然型ヒトアポリポプロテインｅ様蛋白質の産生方法 |
| EP0345155B1 (en) | 1988-05-31 | 1994-08-10 | Mitsubishi Kasei Corporation | Process for producing natural human apolipoprotein e-like proteins |
| AU718382B2 (en) * | 1996-11-08 | 2000-04-13 | Neose Technologies, Inc. | Improved expression vectors |
| US5955310A (en) | 1998-02-26 | 1999-09-21 | Novo Nordisk Biotech, Inc. | Methods for producing a polypeptide in a bacillus cell |
-
2003
- 2003-07-03 WO PCT/US2003/020840 patent/WO2004005221A2/en not_active Ceased
- 2003-07-03 CN CN038206595A patent/CN1678624B/zh not_active Expired - Fee Related
- 2003-07-03 EP EP03763112A patent/EP1539794B1/en not_active Expired - Lifetime
- 2003-07-03 AT AT03763112T patent/ATE419265T1/de not_active IP Right Cessation
- 2003-07-03 DE DE60325611T patent/DE60325611D1/de not_active Expired - Lifetime
- 2003-07-03 AU AU2003256365A patent/AU2003256365B2/en not_active Ceased
- 2003-07-03 JP JP2004519773A patent/JP2006506049A/ja active Pending
- 2003-07-03 CA CA002491056A patent/CA2491056A1/en not_active Abandoned
-
2005
- 2005-01-03 US US11/028,156 patent/US7794972B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1678624B (zh) | 2011-10-26 |
| WO2004005221A3 (en) | 2004-12-02 |
| US20050202544A1 (en) | 2005-09-15 |
| AU2003256365B2 (en) | 2010-02-18 |
| ATE419265T1 (de) | 2009-01-15 |
| CN1678624A (zh) | 2005-10-05 |
| EP1539794B1 (en) | 2008-12-31 |
| WO2004005221A2 (en) | 2004-01-15 |
| DE60325611D1 (de) | 2009-02-12 |
| AU2003256365A1 (en) | 2004-01-23 |
| US7794972B2 (en) | 2010-09-14 |
| EP1539794A4 (en) | 2005-12-28 |
| JP2006506049A (ja) | 2006-02-23 |
| EP1539794A2 (en) | 2005-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |