CA2488121C - Micelle assemblies - Google Patents

Micelle assemblies Download PDF

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Publication number
CA2488121C
CA2488121C CA2488121A CA2488121A CA2488121C CA 2488121 C CA2488121 C CA 2488121C CA 2488121 A CA2488121 A CA 2488121A CA 2488121 A CA2488121 A CA 2488121A CA 2488121 C CA2488121 C CA 2488121C
Authority
CA
Canada
Prior art keywords
compounds
formula
cross
compound
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2488121A
Other languages
English (en)
French (fr)
Other versions
CA2488121A1 (en
Inventor
Kathryn E. Uhrich
Lu Tian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers, The State University of New Jersey
Original Assignee
Rutgers, The State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers, The State University of New Jersey filed Critical Rutgers, The State University of New Jersey
Publication of CA2488121A1 publication Critical patent/CA2488121A1/en
Application granted granted Critical
Publication of CA2488121C publication Critical patent/CA2488121C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
    • C08F290/14—Polymers provided for in subclass C08G
    • C08F290/142—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
CA2488121A 2002-06-07 2003-06-06 Micelle assemblies Expired - Fee Related CA2488121C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38692002P 2002-06-07 2002-06-07
US60/386,920 2002-06-07
PCT/US2003/017902 WO2003103594A2 (en) 2002-06-07 2003-06-06 Micelle assemblies

Publications (2)

Publication Number Publication Date
CA2488121A1 CA2488121A1 (en) 2003-12-18
CA2488121C true CA2488121C (en) 2012-07-24

Family

ID=29736231

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2488121A Expired - Fee Related CA2488121C (en) 2002-06-07 2003-06-06 Micelle assemblies

Country Status (8)

Country Link
US (2) US7470802B2 (cg-RX-API-DMAC10.html)
EP (1) EP1531835B1 (cg-RX-API-DMAC10.html)
JP (1) JP4422018B2 (cg-RX-API-DMAC10.html)
CN (1) CN1735418A (cg-RX-API-DMAC10.html)
AU (1) AU2003238929A1 (cg-RX-API-DMAC10.html)
CA (1) CA2488121C (cg-RX-API-DMAC10.html)
MX (1) MXPA04012290A (cg-RX-API-DMAC10.html)
WO (1) WO2003103594A2 (cg-RX-API-DMAC10.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
EP1734936B1 (en) 2004-01-30 2014-09-10 Rutgers, The State University Amphiphilic star-like or scoprion-like macromolecules, various compositions and uses thereof
US7901705B2 (en) * 2006-02-28 2011-03-08 Tyco Healthcare Group Lp Antimicrobial releasing polymers
WO2009039505A1 (en) * 2007-09-20 2009-03-26 Rutgers, The State University Of New Jersey Compositions and methods for treating cardiovascular conditions
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
WO2011130114A1 (en) * 2010-04-12 2011-10-20 Iowa State University Research Foundation, Inc. Nanoparticles and nanoparticle compositions
US8846850B2 (en) 2011-02-22 2014-09-30 Rutgers, The State University Of New Jersey Amphiphilic macromolecules for nucleic acid delivery
US20120219598A1 (en) * 2011-02-22 2012-08-30 Uhrich Kathryn E Polymeric micelles for reducing ldl in vivo
US9434681B2 (en) 2012-06-15 2016-09-06 Rutgers, The State University Of New Jersey Macromolecules for treating atherosclerosis
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
US9862672B2 (en) 2013-05-29 2018-01-09 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
WO2015195563A1 (en) 2014-06-16 2015-12-23 Rutgers, The State University Of New Jersey Antibacterial agents
US9630905B2 (en) 2014-09-08 2017-04-25 Rutgers, The State University Of New Jersey Amphiphilic macromolecules and methods of use thereof
US10543162B2 (en) 2015-04-10 2020-01-28 Rutgers, The State University Of New Jersey Kojic acid polymers
WO2017165836A1 (en) 2016-03-24 2017-09-28 Rutgers, The State University Of New Jersey Antibacterial agents
SG10201914108RA (en) 2016-08-05 2020-02-27 Rutgers The State University Of New Jersey Thermocleavable friction modifiers and methods thereof
US10744079B2 (en) 2017-08-23 2020-08-18 Colgate-Palmolive Company Oral care compositions and uses thereof
CN113750918B (zh) * 2021-08-17 2022-06-17 常州大学 一种基于小分子非共价后修饰制备补丁状各向异性球状胶束的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065598A (en) * 1975-03-17 1977-12-27 Toray Industries, Inc. Process for polymeric modification of a fiber
JP3070622B2 (ja) 1991-04-25 2000-07-31 川崎製鉄株式会社 プログラマブル論理素子
AU3931093A (en) * 1993-03-19 1994-10-11 Handelman, Joseph H. Topical composition for inhibiting hair growth
US6328988B1 (en) 1999-04-23 2001-12-11 Rutgers, The State University Of New Jersey Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules
US6365146B1 (en) * 1999-04-23 2002-04-02 Rutgers, The State University Of New Jersey Polymer encapsulation of hydrophobic materials
PT1198490E (pt) 1999-07-14 2006-06-30 Alza Corp Lipopolimeros neutros e composicoes liposomais que contem os mesmos
KR20040029359A (ko) * 2001-07-12 2004-04-06 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 약물 전달을 위한 양친매성 별모양 거대분자
US7141540B2 (en) 2001-11-30 2006-11-28 Genta Salus Llc Cyclodextrin grafted biocompatible amphilphilic polymer and methods of preparation and use thereof

Also Published As

Publication number Publication date
MXPA04012290A (es) 2005-04-08
WO2003103594A3 (en) 2004-04-22
EP1531835A2 (en) 2005-05-25
US20060039964A1 (en) 2006-02-23
JP4422018B2 (ja) 2010-02-24
EP1531835B1 (en) 2013-08-07
WO2003103594A2 (en) 2003-12-18
CA2488121A1 (en) 2003-12-18
EP1531835A4 (en) 2006-12-13
US20090175932A1 (en) 2009-07-09
US7470802B2 (en) 2008-12-30
JP2006509050A (ja) 2006-03-16
AU2003238929A1 (en) 2003-12-22
US8192754B2 (en) 2012-06-05
CN1735418A (zh) 2006-02-15

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20190606