CA2487939A1 - Proteines de type semaphorine et methodes d'utilisation de celles-ci - Google Patents

Proteines de type semaphorine et methodes d'utilisation de celles-ci Download PDF

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Publication number
CA2487939A1
CA2487939A1 CA002487939A CA2487939A CA2487939A1 CA 2487939 A1 CA2487939 A1 CA 2487939A1 CA 002487939 A CA002487939 A CA 002487939A CA 2487939 A CA2487939 A CA 2487939A CA 2487939 A1 CA2487939 A1 CA 2487939A1
Authority
CA
Canada
Prior art keywords
cell
novx
tissue
protein
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002487939A
Other languages
English (en)
Inventor
Enrique Alvarez
David W. Anderson
Mohanraj Dhanabal
Nikolai V. Khramtsov
William J. Larochelle
Henri S. Lichenstein
Li Li
Chean Eng Ooi
Muralidhara Padigaru
Richard A. Shimkets
Mei Zhong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/403,676 external-priority patent/US20040029150A1/en
Application filed by Individual filed Critical Individual
Publication of CA2487939A1 publication Critical patent/CA2487939A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Les protéines décrites dans cette invention constituent une famille utilisée pour moduler l'activité de cellules et leur aptitude à attirer les vaisseaux sanguins. Ces protéines sont utilisées pour inhiber l'angiogenèse, la migration cellulaire et la formation de filaments d'actine. Ces protéines servent dans ce contexte à diagnostiquer et à traiter des maladies prolifératives telles que le cancer.
CA002487939A 2002-05-30 2003-05-30 Proteines de type semaphorine et methodes d'utilisation de celles-ci Abandoned CA2487939A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US38479802P 2002-05-30 2002-05-30
US60/384,798 2002-05-30
US40240702P 2002-08-09 2002-08-09
US60/402,407 2002-08-09
US44306203P 2003-01-28 2003-01-28
US60/443,062 2003-01-28
US10/403,676 US20040029150A1 (en) 1999-03-09 2003-03-31 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US10/403,676 2003-03-31
PCT/US2003/017412 WO2003102584A2 (fr) 2002-05-30 2003-05-30 Proteines de type semaphorine et methodes d'utilisation de celles-ci

Publications (1)

Publication Number Publication Date
CA2487939A1 true CA2487939A1 (fr) 2003-12-11

Family

ID=29716299

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002487939A Abandoned CA2487939A1 (fr) 2002-05-30 2003-05-30 Proteines de type semaphorine et methodes d'utilisation de celles-ci

Country Status (5)

Country Link
EP (1) EP1549951A4 (fr)
JP (1) JP2005528434A (fr)
AU (1) AU2003245387A1 (fr)
CA (1) CA2487939A1 (fr)
WO (1) WO2003102584A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2671322A1 (fr) * 2005-12-02 2007-07-12 Regents Of The University Of Colorado Compositions et methodes pour le traitement de problemes medicaux medies par l'actine au moyen d'un agent modulant l'actine
WO2008097503A2 (fr) 2007-02-02 2008-08-14 Biogen Idec Ma Inc. Procédé visant à favoriser la myélinisation et la différentiation oligodendrocytaire

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6900288B1 (en) * 1998-11-26 2005-05-31 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Human semaphorin 6A-1 (SEMA6A-A), a gene involved in neuronal development and regeneration mechanisms during apoptosis, and its use as a potential drug target
US6863889B2 (en) * 1999-03-09 2005-03-08 Curagen Corporation Polynucleotides and proteins encoded thereby
US6689866B1 (en) * 1999-03-09 2004-02-10 Curagen Corporation Polynucleotides and proteins encoded thereby
AU2003230775A1 (en) * 2002-04-01 2003-10-20 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Also Published As

Publication number Publication date
EP1549951A2 (fr) 2005-07-06
WO2003102584A2 (fr) 2003-12-11
JP2005528434A (ja) 2005-09-22
EP1549951A4 (fr) 2006-08-09
WO2003102584A3 (fr) 2004-02-19
AU2003245387A1 (en) 2003-12-19

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Legal Events

Date Code Title Description
FZDE Discontinued