CA2485472C - Secretagogues a hormone de croissance et leurs utilisations - Google Patents
Secretagogues a hormone de croissance et leurs utilisations Download PDFInfo
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- CA2485472C CA2485472C CA2485472A CA2485472A CA2485472C CA 2485472 C CA2485472 C CA 2485472C CA 2485472 A CA2485472 A CA 2485472A CA 2485472 A CA2485472 A CA 2485472A CA 2485472 C CA2485472 C CA 2485472C
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- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
- 229960000553 somatostatin Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000000528 statistical test Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000004797 therapeutic response Effects 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 230000003868 tissue accumulation Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012384 transportation and delivery Methods 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000001755 vocal effect Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention porte sur l'utilisation d'un sécrétagogue de la GH (p. ex. GRF ou un analogue de ce dernier) dans le but (1) de modifier un paramètre lipidique chez un sujet; (2) de modifier un paramètre lié à la composition corporelle d'un sujet, (3) de traiter une affection caractérisée par une formation osseuse déficiente ou réduite chez un sujet, (4) d'améliorer la vigilance diurne et/ou la fonction cognitive d'un sujet, (5) d'améliorer un trouble métabolique chez un sujet, (6) d'améliorer l'anabolisme chez un sujet présentant un trouble du catabolisme, et/ou (7) d'améliorer et/ou de rétablir une fonction immunitaire chez un sujet.
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2485472A CA2485472C (fr) | 2004-10-20 | 2004-10-20 | Secretagogues a hormone de croissance et leurs utilisations |
| MX2007004682A MX2007004682A (es) | 2004-10-20 | 2005-10-20 | Secretagogos de gh y usos de los mismos. |
| CN200580043640XA CN101084009B (zh) | 2003-05-29 | 2005-10-20 | Gh促分泌素及其用途 |
| PCT/CA2005/001611 WO2006042408A1 (fr) | 2004-10-20 | 2005-10-20 | Secretagogues de la gh et utilisations de ceux-ci |
| EP05797145A EP1812048A4 (fr) | 2004-10-20 | 2005-10-20 | Secretagogues de la gh et utilisations de ceux-ci |
| JP2007537087A JP2008516994A (ja) | 2004-10-20 | 2005-10-20 | 成長ホルモン分泌促進因子およびその使用 |
| AU2005297366A AU2005297366B2 (en) | 2004-10-20 | 2005-10-20 | GH secretagogues and uses thereof |
| KR1020077011178A KR101228229B1 (ko) | 2004-10-20 | 2005-10-20 | 성장 호르몬 분비 촉진물질 및 그의 용도 |
| BRPI0516935-6A BRPI0516935A (pt) | 2004-10-20 | 2005-10-20 | secretagogos de gh e usos dos mesmos |
| NO20072136A NO20072136L (no) | 2004-10-20 | 2007-04-24 | Substans som fremmer GH-sekresjon og anvendelse derav |
| HK08106222.9A HK1115803A1 (en) | 2004-10-20 | 2008-06-04 | Gh secretagogues and uses thereof gh |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2485472A CA2485472C (fr) | 2004-10-20 | 2004-10-20 | Secretagogues a hormone de croissance et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2485472A1 CA2485472A1 (fr) | 2006-04-20 |
| CA2485472C true CA2485472C (fr) | 2011-09-27 |
Family
ID=36242546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2485472A Active CA2485472C (fr) | 2003-05-29 | 2004-10-20 | Secretagogues a hormone de croissance et leurs utilisations |
Country Status (4)
| Country | Link |
|---|---|
| BR (1) | BRPI0516935A (fr) |
| CA (1) | CA2485472C (fr) |
| HK (1) | HK1115803A1 (fr) |
| MX (1) | MX2007004682A (fr) |
-
2004
- 2004-10-20 CA CA2485472A patent/CA2485472C/fr active Active
-
2005
- 2005-10-20 BR BRPI0516935-6A patent/BRPI0516935A/pt not_active Application Discontinuation
- 2005-10-20 MX MX2007004682A patent/MX2007004682A/es active IP Right Grant
-
2008
- 2008-06-04 HK HK08106222.9A patent/HK1115803A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007004682A (es) | 2007-07-17 |
| HK1115803A1 (en) | 2008-12-12 |
| BRPI0516935A (pt) | 2008-09-23 |
| CA2485472A1 (fr) | 2006-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |