CA2483392A1 - Analyse informatisee de cellules anormales dans un bloc de cellules - Google Patents
Analyse informatisee de cellules anormales dans un bloc de cellules Download PDFInfo
- Publication number
- CA2483392A1 CA2483392A1 CA002483392A CA2483392A CA2483392A1 CA 2483392 A1 CA2483392 A1 CA 2483392A1 CA 002483392 A CA002483392 A CA 002483392A CA 2483392 A CA2483392 A CA 2483392A CA 2483392 A1 CA2483392 A1 CA 2483392A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- analysis
- tissue according
- cell block
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004458 analytical method Methods 0.000 title claims abstract description 32
- 230000002159 abnormal effect Effects 0.000 title 1
- 239000008188 pellet Substances 0.000 claims abstract description 6
- 230000000877 morphologic effect Effects 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 6
- 238000001574 biopsy Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 101100114828 Drosophila melanogaster Orai gene Proteins 0.000 description 1
- 208000025814 Inflammatory myopathy with abundant macrophages Diseases 0.000 description 1
- 101100270435 Mus musculus Arhgef12 gene Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000006994 Precancerous Conditions Diseases 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000002380 cytological effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000007447 staining method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
- G01N2001/368—Mounting multiple samples in one block, e.g. TMA [Tissue Microarrays]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1477—Multiparameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
Abstract
La présente invention concerne un système d'analyse de blocs de cellules faisant appel à un système informatisé pour examiner un bloc de cellules découpé dans un amas de cellules, le bloc de cellules étant monté sur le système informatisé pour examiner une diversité de caractéristiques comprenant la couleur morphologique et les conditions aux limites entre les cellules. Le bloc de cellules peut être découpé de différentes façons pour présenter différentes caractéristiques à examiner par le système informatisé.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37515002P | 2002-04-22 | 2002-04-22 | |
US60/375,150 | 2002-04-22 | ||
PCT/US2003/012534 WO2003089905A2 (fr) | 2002-04-22 | 2003-04-22 | Analyse informatisee de cellules anormales dans un bloc de cellules |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2483392A1 true CA2483392A1 (fr) | 2003-10-30 |
Family
ID=29251235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002483392A Abandoned CA2483392A1 (fr) | 2002-04-22 | 2003-04-22 | Analyse informatisee de cellules anormales dans un bloc de cellules |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1497644A4 (fr) |
AU (1) | AU2003234180A1 (fr) |
CA (1) | CA2483392A1 (fr) |
WO (1) | WO2003089905A2 (fr) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5740270A (en) * | 1988-04-08 | 1998-04-14 | Neuromedical Systems, Inc. | Automated cytological specimen classification system and method |
US5544650A (en) * | 1988-04-08 | 1996-08-13 | Neuromedical Systems, Inc. | Automated specimen classification system and method |
GB8915759D0 (en) * | 1989-07-10 | 1989-08-31 | Shandon Scient Ltd | Cell block preparation |
US5478722A (en) * | 1991-02-17 | 1995-12-26 | The Curators Of The University Of Missouri | Preserved cell preparations for flow cytometry and immunology |
EP2365311B1 (fr) * | 1998-10-05 | 2013-06-12 | BioPath Automation, L.L.C. | Appareil et procédé pour le prélèvement et manipulation d'echantillons tissulaires en vue d'une analyse de biopsie |
US6300124B1 (en) * | 1999-11-02 | 2001-10-09 | Regents Of The University Of Minnesota | Device and method to directly control the temperature of microscope slides |
-
2003
- 2003-04-22 AU AU2003234180A patent/AU2003234180A1/en not_active Abandoned
- 2003-04-22 WO PCT/US2003/012534 patent/WO2003089905A2/fr not_active Application Discontinuation
- 2003-04-22 EP EP03728489A patent/EP1497644A4/fr not_active Withdrawn
- 2003-04-22 CA CA002483392A patent/CA2483392A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1497644A2 (fr) | 2005-01-19 |
AU2003234180A8 (en) | 2003-11-03 |
WO2003089905A2 (fr) | 2003-10-30 |
EP1497644A4 (fr) | 2007-12-05 |
AU2003234180A1 (en) | 2003-11-03 |
WO2003089905A3 (fr) | 2004-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |