CA2480008C - Utilisation de la sous-unite alpha 2 du recepteur il-13 comme vaccin anti-cancer - Google Patents

Utilisation de la sous-unite alpha 2 du recepteur il-13 comme vaccin anti-cancer Download PDF

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Publication number
CA2480008C
CA2480008C CA2480008A CA2480008A CA2480008C CA 2480008 C CA2480008 C CA 2480008C CA 2480008 A CA2480008 A CA 2480008A CA 2480008 A CA2480008 A CA 2480008A CA 2480008 C CA2480008 C CA 2480008C
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CA
Canada
Prior art keywords
seq
peptide
protein
nucleic acid
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2480008A
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English (en)
Other versions
CA2480008A1 (fr
Inventor
Waldemar Debinski
Neil Christensen
Akiva Mintz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penn State Research Foundation
Original Assignee
Penn State Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Research Foundation filed Critical Penn State Research Foundation
Publication of CA2480008A1 publication Critical patent/CA2480008A1/fr
Application granted granted Critical
Publication of CA2480008C publication Critical patent/CA2480008C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001116Receptors for cytokines
    • A61K39/001119Receptors for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5156Animal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA2480008A 2002-03-22 2002-03-22 Utilisation de la sous-unite alpha 2 du recepteur il-13 comme vaccin anti-cancer Expired - Fee Related CA2480008C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/008983 WO2003092717A1 (fr) 2002-03-22 2002-03-22 Immunotherapie du cancer

Publications (2)

Publication Number Publication Date
CA2480008A1 CA2480008A1 (fr) 2003-11-13
CA2480008C true CA2480008C (fr) 2015-10-06

Family

ID=29398905

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2480008A Expired - Fee Related CA2480008C (fr) 2002-03-22 2002-03-22 Utilisation de la sous-unite alpha 2 du recepteur il-13 comme vaccin anti-cancer

Country Status (5)

Country Link
EP (1) EP1496923A4 (fr)
JP (1) JP2005526842A (fr)
AU (1) AU2002254348B2 (fr)
CA (1) CA2480008C (fr)
WO (1) WO2003092717A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228369A1 (en) * 2005-04-11 2006-10-12 Program For Appropriate Technology In Health Stabilization and preservation of temperature-sensitive vaccines
EP2084267B1 (fr) 2006-09-26 2018-04-11 Cedars-Sinai Medical Center Vaccins comprenant des antigenes de cellules souches cancereuses et procedes
US8871211B2 (en) 2006-09-28 2014-10-28 Cedars-Sinai Medical Center Cancer vaccines and vaccination methods
CN103223165B (zh) * 2007-08-24 2015-02-11 学校法人庆应义塾 肿瘤细胞所导致的免疫抑制的解除剂及使用该解除剂的抗肿瘤剂
US9068020B2 (en) 2008-09-02 2015-06-30 Cedars-Sinai Medical Center CD133 epitopes
ES2662333T3 (es) 2013-02-14 2018-04-06 Immunocellular Therapeutics Ltd. Vacunas contra el cáncer y métodos de vacunación
CN117801069A (zh) * 2016-10-07 2024-04-02 恩特罗姆公司 用于癌症疗法的免疫原性化合物
EP3522917A2 (fr) 2016-10-07 2019-08-14 Enterome S.A. Variants de séquence de microbiote d'épitopes antigéniques associés à une tumeur
IL296165B2 (en) 2016-10-07 2023-10-01 Enterome S A Immunogenic compounds for cancer treatment
EP3480212B1 (fr) * 2017-11-03 2023-09-27 Consejo Superior De Investigaciones Científicas Peptide il13ralpha2 et ses utilisations
CN115427455A (zh) * 2020-05-15 2022-12-02 埃利塞拉疗法公司 抗IL13Rα2抗体、其抗原结合片段和用途
GB202011993D0 (en) 2020-07-31 2020-09-16 Adc Therapeutics Sa ANTI-IL 13Ra2 antibodies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614191A (en) * 1995-03-15 1997-03-25 The United States Of America As Represented By The Department Of Health And Human Services IL-13 receptor specific chimeric proteins and uses thereof
EP1257289A1 (fr) * 2000-02-08 2002-11-20 The Penn State Research Foundation Utilisation du recepteur de l'interleukine 13, sous-unite alpha 2, dans l'immunotherapie

Also Published As

Publication number Publication date
EP1496923A1 (fr) 2005-01-19
CA2480008A1 (fr) 2003-11-13
AU2002254348B2 (en) 2007-12-06
AU2002254348A1 (en) 2003-11-17
JP2005526842A (ja) 2005-09-08
EP1496923A4 (fr) 2005-10-19
WO2003092717A1 (fr) 2003-11-13

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Effective date: 20200831