CA2479835C - An ephrin-b receptor protein involved in carcinoma - Google Patents
An ephrin-b receptor protein involved in carcinoma Download PDFInfo
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- CA2479835C CA2479835C CA2479835A CA2479835A CA2479835C CA 2479835 C CA2479835 C CA 2479835C CA 2479835 A CA2479835 A CA 2479835A CA 2479835 A CA2479835 A CA 2479835A CA 2479835 C CA2479835 C CA 2479835C
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G01N33/57419—Specifically defined cancers of colon
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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| GBGB0208089.3A GB0208089D0 (en) | 2002-04-09 | 2002-04-09 | Protein |
| GB0208089.3 | 2002-04-09 | ||
| PCT/GB2003/001593 WO2003087841A2 (en) | 2002-04-09 | 2003-04-09 | An ephrin-b receptor protein involved in carcinoma |
Publications (2)
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| CA2479835A1 CA2479835A1 (en) | 2003-10-23 |
| CA2479835C true CA2479835C (en) | 2013-10-01 |
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| CA2479835A Expired - Fee Related CA2479835C (en) | 2002-04-09 | 2003-04-09 | An ephrin-b receptor protein involved in carcinoma |
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| AU2006255536A1 (en) | 2005-06-03 | 2006-12-14 | Novartis Vaccines And Diagnostics Inc. | Methods of treating, diagnosing or detecting cancer using an EphB3 modulator |
| WO2008019326A2 (en) * | 2006-08-04 | 2008-02-14 | Novartis Ag | Ephb3-specific antibody and uses thereof |
| BRPI0720437A2 (pt) | 2006-12-07 | 2014-01-07 | Novartis Ag | Anticorpos antafonísticos contra ephb3 |
| US20100041048A1 (en) * | 2008-07-31 | 2010-02-18 | The Johns Hopkins University | Circulating Mutant DNA to Assess Tumor Dynamics |
| EP3558363A1 (en) | 2016-12-21 | 2019-10-30 | Amgen Inc. | Anti-tnf alpha antibody formulations |
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| DE4233782A1 (de) | 1992-10-07 | 1994-04-14 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Klonierung eines neuen Mitgliedes der Familie der Rezeptor-Protein-Tyrosin-Kinasen |
| US5506205A (en) | 1993-11-24 | 1996-04-09 | Ono Pharmaceutical Co., Ltd. | Polypeptide of protein p140 and DNAs encoding it |
| US5457048A (en) | 1993-12-03 | 1995-10-10 | La Jolla Cancer Research Foundation | Eph-related tyrosine kinases, nucleotide sequences and methods of use |
| WO1995028484A1 (en) | 1994-04-15 | 1995-10-26 | Amgen Inc. | Hek5, hek7, hek8, hek11, new eph-like receptor protein tyrosine kinases |
| AU2001243142A1 (en) | 2000-02-03 | 2001-08-14 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| AU5621501A (en) | 2000-03-27 | 2001-10-08 | Bayer Aktiengesellschaft | Regulation of human ephrin-like receptor |
| AUPQ909100A0 (en) | 2000-07-28 | 2000-08-24 | Ludwig Institute For Cancer Research | A method for diagnosis and treatment |
| US20030077568A1 (en) * | 2000-09-15 | 2003-04-24 | Gish Kurt C. | Methods of diagnosis of colorectal cancer, compositions and methods of screening for colorectal cancer modulators |
| AU2002314433A1 (en) | 2001-07-02 | 2003-01-21 | Licentia Ltd. | Ephrin-tie receptor materials and methods |
| WO2006119510A2 (en) * | 2005-05-04 | 2006-11-09 | Receptor Biologix, Inc. | Isoforms of receptor for advanced glycation end products (rage) and methods of identifying and using same |
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2002
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| EP1497659A2 (en) | 2005-01-19 |
| US20110150877A1 (en) | 2011-06-23 |
| US20050260209A1 (en) | 2005-11-24 |
| JP2010101901A (ja) | 2010-05-06 |
| JP2005522229A (ja) | 2005-07-28 |
| WO2003087841A2 (en) | 2003-10-23 |
| CA2479835A1 (en) | 2003-10-23 |
| US7655426B2 (en) | 2010-02-02 |
| AU2003227862A1 (en) | 2003-10-27 |
| AU2003227862B2 (en) | 2008-08-28 |
| GB0208089D0 (en) | 2002-05-22 |
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