CA2477109C - Systeme d'administration de medicaments par voie transvaginale - Google Patents

Systeme d'administration de medicaments par voie transvaginale Download PDF

Info

Publication number
CA2477109C
CA2477109C CA2477109A CA2477109A CA2477109C CA 2477109 C CA2477109 C CA 2477109C CA 2477109 A CA2477109 A CA 2477109A CA 2477109 A CA2477109 A CA 2477109A CA 2477109 C CA2477109 C CA 2477109C
Authority
CA
Canada
Prior art keywords
delivery system
drug
tampon
group
outer layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2477109A
Other languages
English (en)
Other versions
CA2477109A1 (fr
Inventor
Simon Benita
Ram Kluger
Theodor Stern
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Hi Gienic Intra Vaginal Technologies Ltd
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Hi Gienic Intra Vaginal Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem, Hi Gienic Intra Vaginal Technologies Ltd filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of CA2477109A1 publication Critical patent/CA2477109A1/fr
Application granted granted Critical
Publication of CA2477109C publication Critical patent/CA2477109C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/20Tampons, e.g. catamenial tampons; Accessories therefor
    • A61F13/2051Tampons, e.g. catamenial tampons; Accessories therefor characterised by the material or the structure of the inner absorbing core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43Hormones, e.g. dexamethasone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432Inhibitors, antagonists
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/14Female reproductive, genital organs
    • A61M2210/1475Vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un système d'administration de médicaments par voie transvaginale, ce système comprenant : (a) un produit de dépôt comprenant une dose efficace de médicament et, éventuellement, un agent mouillant ; et (b) un support polymère sur lequel est appliqué ledit produit de dépôt. L'invention concerne également un tampon hygiénique à insérer dans le vagin, ce tampon comprenant : (a) un noyau central comprenant une matière absorbante ; (b) une couche externe comprenant une matière perméable aux liquides ; et (c) un système d'administration conforme à l'invention. L'invention concerne en outre une méthode d'administration de médicaments par voie transvaginale.
CA2477109A 2002-02-24 2002-02-24 Systeme d'administration de medicaments par voie transvaginale Expired - Fee Related CA2477109C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2002/000528 WO2003070216A1 (fr) 2002-02-24 2002-02-24 Systeme d'administration de medicaments par voie transvaginale

Publications (2)

Publication Number Publication Date
CA2477109A1 CA2477109A1 (fr) 2003-08-28
CA2477109C true CA2477109C (fr) 2010-11-16

Family

ID=27742202

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2477109A Expired - Fee Related CA2477109C (fr) 2002-02-24 2002-02-24 Systeme d'administration de medicaments par voie transvaginale

Country Status (6)

Country Link
EP (1) EP1478337A1 (fr)
JP (1) JP4663237B2 (fr)
AU (1) AU2002233588B2 (fr)
CA (1) CA2477109C (fr)
IL (1) IL163614A0 (fr)
WO (1) WO2003070216A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100130907A1 (en) 2008-11-21 2010-05-27 Linkel Stephan M Article of manufacture used in contact with human body surfaces

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340055A (en) * 1980-10-01 1982-07-20 Sneider Vincent R Impregnated tampon and method of fabricating same
DE3928677C2 (de) * 1989-08-30 1998-05-14 Kimberly Clark Gmbh Tampon für medizinische oder hygienische Zwecke sowie Verfahren zu seiner Herstellung
JPH0394218U (fr) * 1990-01-18 1991-09-26
JPH07450A (ja) * 1991-05-04 1995-01-06 Mitsugi Takahashi 座薬機能を持った生理用タンポン
US6197327B1 (en) * 1997-06-11 2001-03-06 Umd, Inc. Device and method for treatment of dysmenorrhea
GB0009914D0 (en) * 2000-04-20 2000-06-07 Metris Therapeutics Limited Device
IL138183A0 (en) * 2000-08-31 2001-10-31 Rostam Ltd Ph reducing formulation and delivery system for a tampon
US6888043B2 (en) * 2001-12-21 2005-05-03 Kimberly-Clark Worldwide, Inc. Feminine care products for the delivery of therapeutic substances

Also Published As

Publication number Publication date
EP1478337A1 (fr) 2004-11-24
JP2005535563A (ja) 2005-11-24
CA2477109A1 (fr) 2003-08-28
JP4663237B2 (ja) 2011-04-06
AU2002233588A1 (en) 2003-09-09
WO2003070216A1 (fr) 2003-08-28
AU2002233588B2 (en) 2008-01-31
IL163614A0 (en) 2005-12-18

Similar Documents

Publication Publication Date Title
US7004171B2 (en) System for transvaginal drug delivery
US6086909A (en) Device and method for treatment of dysmenorrhea
EP1200151B1 (fr) Dispositif de délivrance de médicament à inserer dans le vagin, le rectum ou la cavité nasale
US7993667B2 (en) Methods of manufacturing a medicated tampon assembly
AU2005271865B2 (en) Coated vaginal device for delivery of anti-migraine and anti-nausea drugs and a method for treatment of migraine and nausea
AU2002329842B2 (en) Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
Brannon-Peppas Novel vaginal drug release applications
AU2002329842A1 (en) Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
US20050197651A1 (en) Vaginal ring preparation and its application
Dobaria et al. Vaginal drug delivery systems: a review of current status
CA2477109C (fr) Systeme d'administration de medicaments par voie transvaginale
JPH05246841A (ja) 局所用製剤
MXPA99011480A (en) Device and method for treatment of dysmenorrhea
NZ508130A (en) Compositions in the manufacture of a medicament for treatment of dysmenorrhea

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20180226