CA2472880C - Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumours - Google Patents

Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumours Download PDF

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Publication number
CA2472880C
CA2472880C CA2472880A CA2472880A CA2472880C CA 2472880 C CA2472880 C CA 2472880C CA 2472880 A CA2472880 A CA 2472880A CA 2472880 A CA2472880 A CA 2472880A CA 2472880 C CA2472880 C CA 2472880C
Authority
CA
Canada
Prior art keywords
use according
biomaterial
hyaluronic acid
group
epithelium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2472880A
Other languages
English (en)
French (fr)
Other versions
CA2472880A1 (en
Inventor
Norbert E. Fusenig
Hans-Juergen Stark
Michael Willhauck
Alessandra Pavesio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Fidia Farmaceutici SpA
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Fidia Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum DKFZ, Fidia Farmaceutici SpA filed Critical Deutsches Krebsforschungszentrum DKFZ
Publication of CA2472880A1 publication Critical patent/CA2472880A1/en
Application granted granted Critical
Publication of CA2472880C publication Critical patent/CA2472880C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2472880A 2002-01-11 2003-01-07 Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumours Expired - Lifetime CA2472880C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2002PD000003A ITPD20020003A1 (it) 2002-01-11 2002-01-11 Biomateriali a base di acido ialuronico come terapia anti-angiogenicanella cura dei tumori.
ITPD2002A000003 2002-01-11
PCT/EP2003/000078 WO2003057203A2 (en) 2002-01-11 2003-01-07 Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumours

Publications (2)

Publication Number Publication Date
CA2472880A1 CA2472880A1 (en) 2003-07-17
CA2472880C true CA2472880C (en) 2011-08-16

Family

ID=11452500

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2472880A Expired - Lifetime CA2472880C (en) 2002-01-11 2003-01-07 Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumours

Country Status (12)

Country Link
US (1) US7838510B2 (enExample)
EP (1) EP1463541B1 (enExample)
JP (1) JP4603263B2 (enExample)
AT (1) ATE448809T1 (enExample)
AU (1) AU2003201618B2 (enExample)
CA (1) CA2472880C (enExample)
DE (1) DE60330113D1 (enExample)
DK (1) DK1463541T3 (enExample)
ES (1) ES2334497T3 (enExample)
IT (1) ITPD20020003A1 (enExample)
PT (1) PT1463541E (enExample)
WO (1) WO2003057203A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD20040312A1 (it) * 2004-12-15 2005-03-15 Fidia Advanced Biopolymers Srl Protesi e o supporto per la sostituzione, riparazione, rigenerazione del menisco

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6117A (ja) * 1984-06-11 1986-01-06 Seikagaku Kogyo Co Ltd ムコ多糖系癌転移抑制剤
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
IT1254704B (it) * 1991-12-18 1995-10-09 Mini Ricerca Scient Tecnolog Tessuto non tessuto essenzialmente costituito da derivati dell'acido ialuronico
CA2094203A1 (en) * 1993-04-16 1994-10-17 Derek A. Willoughby Inhibition of angiogenesis
ITPD940054A1 (it) * 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
IL123500A (en) * 1995-08-29 2003-06-24 Fidia Advanced Biopolymers Srl Composite biomaterials for preventing post-surgical adhesions of tissues
US6579978B1 (en) * 1997-04-04 2003-06-17 Fidia Farmaceuti S.P.A. Biomaterials comprising N-sulphated hyaluronic acid compounds or derivatives thereof
IT1293484B1 (it) * 1997-06-11 1999-03-01 Fidia Advanced Biopolymers Srl Materiale biologico comprendente una efficiente coltura di cellule e una matrice tridimensionale biocompatibile e biodegradabile
US6872819B1 (en) * 1998-05-27 2005-03-29 Fidia Advanced Biopolymers S.R.L. Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
WO2000054762A2 (en) * 1999-03-15 2000-09-21 Trustees Of Boston University Use of cross linked polysaccharides for the inhibition of angiogenesis
CA2366604A1 (en) 1999-03-26 2000-10-05 The University Of Texas System Modulators of polysaccharides and uses thereof
IT1317359B1 (it) * 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Polisaccaridi percarbossilati, quali l'acido ialuronico, processo perla loro preparazione e loro impiego in campo farmaceutico e
IT1317358B1 (it) * 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Derivati cross-linkati dell'acido ialuronico.
WO2002041877A1 (en) * 2000-10-24 2002-05-30 Clear Solutions Biotech, Inc. Sodium hyaluronate microspheres

Also Published As

Publication number Publication date
US7838510B2 (en) 2010-11-23
ATE448809T1 (de) 2009-12-15
EP1463541B1 (en) 2009-11-18
ITPD20020003A1 (it) 2003-07-11
US20050037049A1 (en) 2005-02-17
CA2472880A1 (en) 2003-07-17
DK1463541T3 (da) 2010-03-08
AU2003201618B2 (en) 2008-11-06
ES2334497T3 (es) 2010-03-11
WO2003057203A3 (en) 2003-12-31
DE60330113D1 (de) 2009-12-31
WO2003057203A2 (en) 2003-07-17
JP4603263B2 (ja) 2010-12-22
EP1463541A2 (en) 2004-10-06
JP2005524619A (ja) 2005-08-18
AU2003201618A1 (en) 2003-07-24
PT1463541E (pt) 2010-01-07

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Effective date: 20230109