CA2471686C - Reducing working fluid dilution in liquid systems - Google Patents
Reducing working fluid dilution in liquid systems Download PDFInfo
- Publication number
- CA2471686C CA2471686C CA 2471686 CA2471686A CA2471686C CA 2471686 C CA2471686 C CA 2471686C CA 2471686 CA2471686 CA 2471686 CA 2471686 A CA2471686 A CA 2471686A CA 2471686 C CA2471686 C CA 2471686C
- Authority
- CA
- Canada
- Prior art keywords
- fluid
- segment
- sample
- buffer
- working fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 238000012360 testing method Methods 0.000 claims abstract description 19
- 210000004369 blood Anatomy 0.000 claims abstract description 10
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
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- 239000011780 sodium chloride Substances 0.000 description 2
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- 229910052734 helium Inorganic materials 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
- Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/464,156 | 2003-06-18 | ||
| US10/464,156 US7247487B2 (en) | 2003-06-18 | 2003-06-18 | Reducing working fluid dilution in liquid systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2471686A1 CA2471686A1 (en) | 2004-12-18 |
| CA2471686C true CA2471686C (en) | 2014-08-12 |
Family
ID=33418150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2471686 Expired - Fee Related CA2471686C (en) | 2003-06-18 | 2004-06-18 | Reducing working fluid dilution in liquid systems |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7247487B2 (enExample) |
| EP (1) | EP1489303B1 (enExample) |
| JP (1) | JP4494877B2 (enExample) |
| KR (1) | KR101140439B1 (enExample) |
| AU (1) | AU2004202662B2 (enExample) |
| CA (1) | CA2471686C (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107206382A (zh) * | 2015-02-13 | 2017-09-26 | 西门子医疗保健诊断公司 | 在移液操作期间提供减少的残留的方法和设备 |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6524456B1 (en) * | 1999-08-12 | 2003-02-25 | Ut-Battelle, Llc | Microfluidic devices for the controlled manipulation of small volumes |
| WO2003099407A2 (de) * | 2002-05-24 | 2003-12-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zum mischungsfreien übertragen von heterogenen flüssigkeiten in mikrokanälen |
| WO2005072858A1 (en) | 2004-01-26 | 2005-08-11 | President And Fellows Of Harvard College | Fluid delivery system and method |
| EP1672674A1 (de) * | 2004-12-17 | 2006-06-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Untersuchungsverfahren und -system zur Hochdurchsatzmassenanalyse |
| AU2006236410B2 (en) | 2005-04-19 | 2012-11-01 | President And Fellows Of Harvard College | Fluidic structures including meandering and wide channels |
| US20060280029A1 (en) * | 2005-06-13 | 2006-12-14 | President And Fellows Of Harvard College | Microfluidic mixer |
| WO2007024778A2 (en) * | 2005-08-22 | 2007-03-01 | Applera Corporation | Device, system and method for depositing processed immiscible-fluid-discrete-volumes |
| JP4915690B2 (ja) * | 2006-05-23 | 2012-04-11 | 国立大学法人電気通信大学 | マイクロ化学チップ装置 |
| JP4968896B2 (ja) * | 2006-09-27 | 2012-07-04 | 富士フイルム株式会社 | 分散液製造装置及び分散液製造方法 |
| JPWO2008047533A1 (ja) * | 2006-10-18 | 2010-02-25 | コニカミノルタエムジー株式会社 | マイクロチップ反応検出システム、マイクロチップの流路内における反応方法 |
| US7803101B2 (en) * | 2007-01-30 | 2010-09-28 | Ortho-Clinical Diagnostics, Inc. | Random access multi-disc centrifuge |
| US7850917B2 (en) * | 2008-03-11 | 2010-12-14 | Ortho-Clinical Diagnostics, Inc. | Particle agglutination in a tip |
| FR2933315B1 (fr) * | 2008-07-07 | 2012-02-10 | Commissariat Energie Atomique | Dispositif microfluidique de deplacement de liquide |
| FR2934361B1 (fr) * | 2008-07-22 | 2012-12-28 | Commissariat Energie Atomique | Dispositif de variation de pression d'un fluide pneumatique par deplacement de gouttes de liquide et pompe a chaleur utilisant un tel dispositif |
| JP4919119B2 (ja) * | 2010-01-19 | 2012-04-18 | 株式会社日立プラントテクノロジー | 試薬分注ノズルによる分取・分注方法および試薬分取・分注機構 |
| US8365616B1 (en) | 2010-09-16 | 2013-02-05 | Wolcott Duane K | Sampling probe for solutions containing soluble solids or high concentrations of dissolved solids |
| AU2012327218C1 (en) | 2011-11-30 | 2015-12-24 | Wellstat Diagnostics, Llc. | Filtration Module |
| ES2691212T3 (es) * | 2012-01-31 | 2018-11-26 | Siemens Healthcare Diagnostics Products Gmbh | Procedimiento para calentar un volumen de líquido en una aguja de pipeteado calentada, dispositivo de pipeteado y aparato de análisis automático |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| US9081001B2 (en) | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| CA2900708C (en) | 2013-03-13 | 2021-06-15 | Opko Diagnostics, Llc | Mixing of fluids in fluidic systems |
| US9625378B2 (en) | 2014-03-31 | 2017-04-18 | Redshift Bioanalytics, Inc. | Fluid analyzer with modulation for liquids and gases |
| EA038479B1 (ru) | 2014-12-12 | 2021-09-03 | Опкоу Дайагностикс, Ллк | Устройство для проведения анализа пробы и способ эксплуатации указанного устройства |
| KR101779087B1 (ko) * | 2016-03-10 | 2017-09-18 | 조선대학교산학협력단 | Ｐｏｃｔ 기반 혈액생물성치 측정장치 및 측정방법 |
| CN117253055A (zh) | 2016-10-28 | 2023-12-19 | 贝克曼库尔特有限公司 | 物质准备评估系统 |
| WO2023288323A2 (en) * | 2021-07-15 | 2023-01-19 | Techcyte, Inc. | Image analysis for classifying hemagglutination and quantifying presence of antibodies |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US482599A (en) * | 1892-09-13 | Traction-engine | ||
| US2797149A (en) | 1953-01-08 | 1957-06-25 | Technicon International Ltd | Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents |
| US2879141A (en) | 1955-11-16 | 1959-03-24 | Technicon Instr | Automatic analyzing apparatus |
| US3479141A (en) | 1967-05-17 | 1969-11-18 | Technicon Corp | Method and apparatus for analysis |
| US3992158A (en) | 1973-08-16 | 1976-11-16 | Eastman Kodak Company | Integral analytical element |
| US3991055A (en) * | 1975-05-30 | 1976-11-09 | Coulter Electronics, Inc. | Liquid transfer valve |
| US4121466A (en) * | 1977-04-19 | 1978-10-24 | Technicon Instruments Corporation | Liquid dispenser with an improved probe |
| US4259291A (en) | 1979-07-13 | 1981-03-31 | Technicon Instruments Corporation | Metering device |
| US4526754A (en) * | 1982-07-30 | 1985-07-02 | Technicon Instruments Corporation | Sample transport system |
| US4853336A (en) | 1982-11-15 | 1989-08-01 | Technicon Instruments Corporation | Single channel continuous flow system |
| US4574850A (en) * | 1985-01-17 | 1986-03-11 | E. I. Du Pont De Nemours And Company | Method of and apparatus for dispensing liquid |
| WO1988004052A1 (en) | 1986-11-19 | 1988-06-02 | Technicon Instruments Corporation | Method and apparatus for conveying information in a liquid sample transport system |
| US4984475A (en) * | 1989-07-24 | 1991-01-15 | Tritech Partners | Ultra low carryover sample liquid analysis apparatus and method |
| US5399497A (en) * | 1992-02-26 | 1995-03-21 | Miles, Inc. | Capsule chemistry sample liquid analysis system and method |
| US5646049A (en) | 1992-03-27 | 1997-07-08 | Abbott Laboratories | Scheduling operation of an automated analytical system |
| US5552064A (en) | 1993-02-26 | 1996-09-03 | Ortho Diagnostic Systems, Inc. | Column agglutination assay and device using biphasic centrifugation |
| US5441895A (en) | 1993-12-07 | 1995-08-15 | Jakubowicz; Raymond F. | Reagent cup shape allowing stacking without dislodging reagent |
| JPH07159415A (ja) * | 1993-12-08 | 1995-06-23 | Hitachi Ltd | 自動試料導入方法 |
| AU702403B2 (en) | 1995-12-05 | 1999-02-18 | Gamera Bioscience | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
| WO1997039359A1 (en) * | 1996-04-15 | 1997-10-23 | Dade International Inc. | Apparatus and method for analysis |
| CN1329729C (zh) * | 1996-06-28 | 2007-08-01 | 卡钳生命科学股份有限公司 | 微流体系统 |
| US5992820A (en) | 1997-11-19 | 1999-11-30 | Sarnoff Corporation | Flow control in microfluidics devices by controlled bubble formation |
| US6348354B1 (en) * | 1998-07-06 | 2002-02-19 | Bayer Corporation | Method and apparatus for controlling a stream of liquid test packages in a capsule chemistry analysis system |
| US6524456B1 (en) * | 1999-08-12 | 2003-02-25 | Ut-Battelle, Llc | Microfluidic devices for the controlled manipulation of small volumes |
| US6610499B1 (en) | 2000-08-31 | 2003-08-26 | The Regents Of The University Of California | Capillary array and related methods |
| US6453928B1 (en) | 2001-01-08 | 2002-09-24 | Nanolab Ltd. | Apparatus, and method for propelling fluids |
| US7077152B2 (en) * | 2001-07-07 | 2006-07-18 | Nanostream, Inc. | Microfluidic metering systems and methods |
| FR2829948B1 (fr) * | 2001-09-21 | 2004-07-09 | Commissariat Energie Atomique | Procede de deplacement d'un fluide d'interet dans un capillaire et microsysteme fluidique |
-
2003
- 2003-06-18 US US10/464,156 patent/US7247487B2/en not_active Expired - Fee Related
-
2004
- 2004-06-17 KR KR1020040045130A patent/KR101140439B1/ko not_active Expired - Fee Related
- 2004-06-17 AU AU2004202662A patent/AU2004202662B2/en not_active Ceased
- 2004-06-17 EP EP20040253624 patent/EP1489303B1/en not_active Expired - Lifetime
- 2004-06-18 JP JP2004181332A patent/JP4494877B2/ja not_active Expired - Fee Related
- 2004-06-18 CA CA 2471686 patent/CA2471686C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107206382A (zh) * | 2015-02-13 | 2017-09-26 | 西门子医疗保健诊断公司 | 在移液操作期间提供减少的残留的方法和设备 |
| US10802034B2 (en) | 2015-02-13 | 2020-10-13 | Siemens Healthcare Diagnostics Inc. | Methods and apparatus providing reduced carryover during pipetting operations |
Also Published As
| Publication number | Publication date |
|---|---|
| US7247487B2 (en) | 2007-07-24 |
| KR20040111119A (ko) | 2004-12-31 |
| JP2005010165A (ja) | 2005-01-13 |
| US20040259268A1 (en) | 2004-12-23 |
| EP1489303A2 (en) | 2004-12-22 |
| EP1489303B1 (en) | 2013-11-06 |
| KR101140439B1 (ko) | 2012-04-30 |
| AU2004202662B2 (en) | 2009-09-10 |
| AU2004202662A1 (en) | 2005-01-13 |
| JP4494877B2 (ja) | 2010-06-30 |
| CA2471686A1 (en) | 2004-12-18 |
| EP1489303A3 (en) | 2007-03-21 |
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| EEER | Examination request | ||
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