CA2462670A1 - Sperm-specific cation channel, catsper2, and uses therefor - Google Patents

Sperm-specific cation channel, catsper2, and uses therefor Download PDF

Info

Publication number
CA2462670A1
CA2462670A1 CA002462670A CA2462670A CA2462670A1 CA 2462670 A1 CA2462670 A1 CA 2462670A1 CA 002462670 A CA002462670 A CA 002462670A CA 2462670 A CA2462670 A CA 2462670A CA 2462670 A1 CA2462670 A1 CA 2462670A1
Authority
CA
Canada
Prior art keywords
catsper2
seq
protein
sequence
residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002462670A
Other languages
English (en)
French (fr)
Inventor
Dejian Ren
David E. Clapham
David L. Garbers
Timothy A. Quill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Children's Hospital
The University of Texas System
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2462670A1 publication Critical patent/CA2462670A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002462670A 2001-10-22 2002-10-22 Sperm-specific cation channel, catsper2, and uses therefor Abandoned CA2462670A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34532401P 2001-10-22 2001-10-22
US60/345,324 2001-10-22
PCT/US2002/033676 WO2003054141A2 (en) 2001-10-22 2002-10-22 Sperm-specific cation channel, catsper2, and uses therefor

Publications (1)

Publication Number Publication Date
CA2462670A1 true CA2462670A1 (en) 2003-07-03

Family

ID=23354573

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002462670A Abandoned CA2462670A1 (en) 2001-10-22 2002-10-22 Sperm-specific cation channel, catsper2, and uses therefor

Country Status (7)

Country Link
US (1) US7339029B2 (enExample)
EP (1) EP1448589A4 (enExample)
JP (1) JP2005512561A (enExample)
AU (1) AU2002364939A1 (enExample)
CA (1) CA2462670A1 (enExample)
MX (1) MXPA04003750A (enExample)
WO (1) WO2003054141A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8729248B2 (en) 2001-10-22 2014-05-20 Children's Medical Center Corporation Sperm-specific cation channel, CATSPER2, and uses therefor
US20050202539A1 (en) * 2004-03-11 2005-09-15 Hydra Biosciences System for screening eukaryotic membrane proteins
AU2005301152A1 (en) * 2004-10-29 2006-05-11 Genentech, Inc. Disruptions of genes encoding secreted proteins, compositions and methods relating thereto
AU2006259368A1 (en) 2005-06-15 2006-12-28 Hydra Biosciences, Inc. Modulators of sperm hypermotility and uses thereof
WO2014070786A1 (en) 2012-10-29 2014-05-08 The University Of North Carolina At Chapel Hill Compositions and methods for inhibiting pathogen infection
CN113166236A (zh) 2018-09-21 2021-07-23 北卡罗来纳大学查佩尔希尔分校 限制穿过黏液的合成粘合剂
WO2020193446A1 (en) * 2019-03-22 2020-10-01 Westfälische Wilhelms-Universität Münster Catsper-activity-test for determining male infertility

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001054477A2 (en) 2000-01-25 2001-08-02 Hyseq, Inc. Novel nucleic acids and polypeptides
EP1171460A4 (en) * 1999-04-09 2002-10-09 Human Genome Sciences Inc 48 HUMAN SECRETED PROTEINS
CA2378403A1 (en) 1999-07-26 2001-02-01 Genentech, Inc. Novel polynucleotides and method for the use thereof
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
AU2001274888A1 (en) * 2000-05-19 2001-12-03 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
EP1430125A4 (en) * 2001-05-03 2005-01-19 Childrens Medical Center SPERM SPECIFIC CATION CHANNEL AND USES THEREOF
WO2003089583A2 (en) * 2002-04-16 2003-10-30 Origene Technologies, Inc. Tissue specific genes and gene clusters
AU2003235096A1 (en) 2002-04-24 2003-11-10 Takeda Chemical Industries, Ltd. Novel protein and dna thereof
GB0212067D0 (en) * 2002-05-24 2002-07-03 Impharmatica Ltd Proteins
WO2004023973A2 (en) * 2002-09-12 2004-03-25 Incyte Corporation Molecules for diagnostics and therapeutics

Also Published As

Publication number Publication date
JP2005512561A (ja) 2005-05-12
EP1448589A2 (en) 2004-08-25
US7339029B2 (en) 2008-03-04
WO2003054141A3 (en) 2004-03-11
AU2002364939A1 (en) 2003-07-09
MXPA04003750A (es) 2004-07-23
US20050142566A1 (en) 2005-06-30
EP1448589A4 (en) 2005-03-30
WO2003054141A2 (en) 2003-07-03

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued