CA2454427A1 - Nouveau recepteur couple aux proteines g, gave8 - Google Patents

Nouveau recepteur couple aux proteines g, gave8 Download PDF

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Publication number
CA2454427A1
CA2454427A1 CA002454427A CA2454427A CA2454427A1 CA 2454427 A1 CA2454427 A1 CA 2454427A1 CA 002454427 A CA002454427 A CA 002454427A CA 2454427 A CA2454427 A CA 2454427A CA 2454427 A1 CA2454427 A1 CA 2454427A1
Authority
CA
Canada
Prior art keywords
gave8
protein
nucleic acid
cell
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002454427A
Other languages
English (en)
Inventor
Haifeng Eishingdrelo
Jidong Cai
Ali Ardati
Anthony Sandrasagra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0125704.7A external-priority patent/GB0125704D0/en
Application filed by Individual filed Critical Individual
Publication of CA2454427A1 publication Critical patent/CA2454427A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne de nouveaux polypeptides, des protéines et des molécules d'acide nucléique GAVE8. L'invention concerne également des protéines GAVE8 pleine longueur isolées, des protéines hybrides GAVE8 isolées, des peptides antigéniques et des anticorps anti-GAVE8. L'invention concerne également des molécules d'acide nucléique GAVE8, des vecteurs d'expression recombinés contenant cette molécule d'acide nucléique, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits et des animaux transgénique non humains dans lesquels le gène GAVE8 a été introduit ou interrompu. L'invention concerne également des méthodes de diagnostic, de criblage et de thérapie faisant intervenir des compositions ou des molécules GAVE8 fixant GAVE8. L'invention concerne également des méthodes destinées à l'identification d'agonistes, d'antagonistes, d'agonistes inverses de GAVE8 et d'éléments analogues.
CA002454427A 2001-07-20 2002-07-19 Nouveau recepteur couple aux proteines g, gave8 Abandoned CA2454427A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30643401P 2001-07-20 2001-07-20
US60/306,434 2001-07-20
GB0125704.7 2001-10-26
GBGB0125704.7A GB0125704D0 (en) 2001-07-20 2001-10-26 A novel g protein-coupled receptor gaves
PCT/US2002/023208 WO2003008560A2 (fr) 2001-07-20 2002-07-19 Nouveau recepteur couple aux proteines g, gave8

Publications (1)

Publication Number Publication Date
CA2454427A1 true CA2454427A1 (fr) 2003-01-30

Family

ID=26246697

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002454427A Abandoned CA2454427A1 (fr) 2001-07-20 2002-07-19 Nouveau recepteur couple aux proteines g, gave8

Country Status (9)

Country Link
EP (1) EP1448583A4 (fr)
JP (1) JP2005522184A (fr)
BR (1) BR0211338A (fr)
CA (1) CA2454427A1 (fr)
IL (1) IL159939A0 (fr)
MX (1) MXPA04000437A (fr)
NO (1) NO20040252L (fr)
TW (1) TWI250209B (fr)
WO (1) WO2003008560A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1237909A2 (fr) * 1999-11-16 2002-09-11 PHARMACIA & UPJOHN COMPANY Recepteurs couples a une proteine g
WO2001081573A1 (fr) * 2000-04-26 2001-11-01 Aventis Pharma Deutschland Gmbh Recepteur edg8, sa preparation et son utilisation
AU2001276837A1 (en) * 2000-06-23 2002-01-08 Tularik, Inc. Human and mouse g-protein couipled receptors

Also Published As

Publication number Publication date
WO2003008560A8 (fr) 2004-06-24
EP1448583A2 (fr) 2004-08-25
NO20040252L (no) 2004-03-19
WO2003008560A2 (fr) 2003-01-30
TWI250209B (en) 2006-03-01
BR0211338A (pt) 2004-11-16
JP2005522184A (ja) 2005-07-28
EP1448583A4 (fr) 2006-02-08
IL159939A0 (en) 2004-06-20
MXPA04000437A (es) 2004-03-18

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued