CA2448102A1 - Novel mixed lineage kinase (7) (mlk7) polypeptide, polynucleotides encoding the same, and methods of use thereof - Google Patents

Novel mixed lineage kinase (7) (mlk7) polypeptide, polynucleotides encoding the same, and methods of use thereof Download PDF

Info

Publication number
CA2448102A1
CA2448102A1 CA002448102A CA2448102A CA2448102A1 CA 2448102 A1 CA2448102 A1 CA 2448102A1 CA 002448102 A CA002448102 A CA 002448102A CA 2448102 A CA2448102 A CA 2448102A CA 2448102 A1 CA2448102 A1 CA 2448102A1
Authority
CA
Canada
Prior art keywords
leu
ser
ala
polypeptide
mlk7
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002448102A
Other languages
English (en)
French (fr)
Inventor
Thelma S. Angeles
John T. Durkin
Beverly P. Holskin
Sheryl L. Meyer
Chrysanthe M. Spais
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2448102A1 publication Critical patent/CA2448102A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002448102A 2001-05-24 2002-05-23 Novel mixed lineage kinase (7) (mlk7) polypeptide, polynucleotides encoding the same, and methods of use thereof Abandoned CA2448102A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29338101P 2001-05-24 2001-05-24
US60/293,381 2001-05-24
PCT/US2002/016387 WO2002095017A1 (en) 2001-05-24 2002-05-23 Novel mixed lineage kinase (7) (mlk7) polypeptide, polynucleotides encoding the same, and methods of use thereof

Publications (1)

Publication Number Publication Date
CA2448102A1 true CA2448102A1 (en) 2002-11-28

Family

ID=23128847

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002448102A Abandoned CA2448102A1 (en) 2001-05-24 2002-05-23 Novel mixed lineage kinase (7) (mlk7) polypeptide, polynucleotides encoding the same, and methods of use thereof

Country Status (6)

Country Link
US (1) US20040185460A1 (enExample)
EP (1) EP1402009A4 (enExample)
JP (1) JP2004537291A (enExample)
CA (1) CA2448102A1 (enExample)
MX (1) MXPA03010706A (enExample)
WO (1) WO2002095017A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005103240A1 (en) * 2004-04-24 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with casein kinase 1, delta, isoform 1 (csnk1d iso 1)
US9061009B2 (en) * 2007-06-08 2015-06-23 University Of Massachusetts Mixed lineage kinases and metabolic disorders
EP2602993A1 (en) * 2011-12-08 2013-06-12 Research In Motion Limited Apparatus and associated method for face tracking in video conference and video chat communications

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4879236A (en) * 1984-05-16 1989-11-07 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US6514745B1 (en) * 1993-07-19 2003-02-04 The Regents Of The University Of California Oncoprotein protein kinase
US5534426A (en) * 1993-07-19 1996-07-09 The Regents Of The University Of California Oncoprotein protein kinase
US5554523A (en) * 1994-03-01 1996-09-10 Children's Hospital Of Philadelphia Nucleic acid sequences encoding human leucine-zipper protein-kinase
US5817479A (en) * 1996-08-07 1998-10-06 Incyte Pharmaceuticals, Inc. Human kinase homologs
AU2001234544A1 (en) * 2000-01-25 2001-08-07 Sugen, Inc. Novel human protein kinases and protein kinase-like enzymes
AU2002303258A1 (en) * 2001-04-06 2002-10-28 Incyte Genomics, Inc. Kinases and phosphatases
AU2003225535A1 (en) * 2002-01-31 2003-09-02 Millennium Pharmaceuticals, Inc. Methods and compositions for treating cancer

Also Published As

Publication number Publication date
MXPA03010706A (es) 2004-05-27
WO2002095017A1 (en) 2002-11-28
EP1402009A4 (en) 2005-02-02
JP2004537291A (ja) 2004-12-16
EP1402009A1 (en) 2004-03-31
US20040185460A1 (en) 2004-09-23

Similar Documents

Publication Publication Date Title
CA2209426C (en) Human pak65
Tan et al. Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton
Gijsbers et al. Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1
US6969596B2 (en) Polynucleotide encoding a human receptor tyrosine kinase
EP2534258B1 (en) Dual activity kinase domains and uses thereof
WO1999011795A1 (en) Mammalian chk1 effector cell-cycle checkpoint protein kinase materials and methods
WO1999053076A9 (en) Tao protein kinases and methods of use therefor
US6048706A (en) Human PAK65
US20040185460A1 (en) Novel mixed lineage kinase (7) (mlk7) polypeptide polynucleotides encoding the same and methods of use thereof
JP2003519472A (ja) P21活性化キナーゼ(pak)タンパク質ファミリーの一つであるpak5、これに関する核酸および方法
JP2001157590A (ja) 紫外線照射仲介皮膚損傷に関連する遺伝子およびポリヌクレオチド並びにそれらの使用
US6660483B1 (en) Diagnostic marker for neurological conditions
US20060110769A1 (en) Regulation of novel human prolyl 4-hydroxylases
EP1294753B1 (en) A human homologue of the db4/ask1 protein, nucleic acids, and methods related to the same
US20040019918A1 (en) Human MEKK2 protein and nucleic acid molecules and uses therefor
AU9395098A (en) Compositions and methods for identifying pkb kinase inhibitors
US20030064496A1 (en) Human MEKK2 protein and nucleic acid molecules and uses therefor
US20040121383A1 (en) Compositions, organisms and methodologies employing a novel human kinase
KR19990086092A (ko) 발암 효과가 증진된 돌연변이 cdk4 유전자, 그 효소 단백질및 그의 제조방법

Legal Events

Date Code Title Description
FZDE Discontinued