CA2445612C - Methods and compositions for treating mammalian nerve tissue injuries - Google Patents

Methods and compositions for treating mammalian nerve tissue injuries Download PDF

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Publication number
CA2445612C
CA2445612C CA2445612A CA2445612A CA2445612C CA 2445612 C CA2445612 C CA 2445612C CA 2445612 A CA2445612 A CA 2445612A CA 2445612 A CA2445612 A CA 2445612A CA 2445612 C CA2445612 C CA 2445612C
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CA
Canada
Prior art keywords
injury
peg
spinal cord
glycol
fusion agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2445612A
Other languages
English (en)
French (fr)
Other versions
CA2445612A1 (en
Inventor
Riyi Shi
Richard B. Borgens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
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Purdue Research Foundation
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Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Priority to CA2740056A priority Critical patent/CA2740056A1/en
Publication of CA2445612A1 publication Critical patent/CA2445612A1/en
Application granted granted Critical
Publication of CA2445612C publication Critical patent/CA2445612C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2445612A 2001-04-24 2002-04-24 Methods and compositions for treating mammalian nerve tissue injuries Expired - Fee Related CA2445612C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2740056A CA2740056A1 (en) 2001-04-24 2002-04-24 Methods and compositions for treating mammalian nerve tissue injuries

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28620001P 2001-04-24 2001-04-24
US60/286,200 2001-04-24
PCT/US2002/013375 WO2002092107A1 (en) 2001-04-24 2002-04-24 Method and compositions for treating mammalian nerve tissue injuries

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2740056A Division CA2740056A1 (en) 2001-04-24 2002-04-24 Methods and compositions for treating mammalian nerve tissue injuries

Publications (2)

Publication Number Publication Date
CA2445612A1 CA2445612A1 (en) 2002-11-21
CA2445612C true CA2445612C (en) 2011-10-25

Family

ID=23097525

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2445612A Expired - Fee Related CA2445612C (en) 2001-04-24 2002-04-24 Methods and compositions for treating mammalian nerve tissue injuries
CA2740056A Abandoned CA2740056A1 (en) 2001-04-24 2002-04-24 Methods and compositions for treating mammalian nerve tissue injuries

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2740056A Abandoned CA2740056A1 (en) 2001-04-24 2002-04-24 Methods and compositions for treating mammalian nerve tissue injuries

Country Status (9)

Country Link
US (4) US7837987B2 (https=)
EP (1) EP1389121B1 (https=)
JP (2) JP2004527573A (https=)
AT (1) ATE546146T1 (https=)
AU (2) AU2002314758B2 (https=)
CA (2) CA2445612C (https=)
ES (1) ES2382899T3 (https=)
NZ (2) NZ543953A (https=)
WO (1) WO2002092107A1 (https=)

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Also Published As

Publication number Publication date
US9101655B2 (en) 2015-08-11
AU2006200866A1 (en) 2006-03-23
US7837987B2 (en) 2010-11-23
US20140100289A1 (en) 2014-04-10
JP2004527573A (ja) 2004-09-09
EP1389121A1 (en) 2004-02-18
AU2006200866B2 (en) 2007-11-08
US9687502B2 (en) 2017-06-27
JP2009112835A (ja) 2009-05-28
WO2002092107A1 (en) 2002-11-21
US20100016444A1 (en) 2010-01-21
AU2002314758B2 (en) 2006-06-01
NZ529526A (en) 2006-06-30
NZ543953A (en) 2007-04-27
US20030118545A1 (en) 2003-06-26
EP1389121A4 (en) 2006-11-02
US8460646B2 (en) 2013-06-11
EP1389121B1 (en) 2012-02-22
CA2445612A1 (en) 2002-11-21
CA2740056A1 (en) 2002-11-21
ES2382899T3 (es) 2012-06-14
US20050069520A1 (en) 2005-03-31
ATE546146T1 (de) 2012-03-15

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