CA2440713A1 - Forme posologique orale contenant de la nicotine - Google Patents

Forme posologique orale contenant de la nicotine Download PDF

Info

Publication number
CA2440713A1
CA2440713A1 CA002440713A CA2440713A CA2440713A1 CA 2440713 A1 CA2440713 A1 CA 2440713A1 CA 002440713 A CA002440713 A CA 002440713A CA 2440713 A CA2440713 A CA 2440713A CA 2440713 A1 CA2440713 A1 CA 2440713A1
Authority
CA
Canada
Prior art keywords
nicotine
dosage form
active
sugar alcohol
oral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002440713A
Other languages
English (en)
Inventor
John Liu
Stanley J. Lech
Stuart Platcow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2440713A1 publication Critical patent/CA2440713A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des formes posologiques solides à administration orale, comprenant une matrice vitreuse, qui sont utiles pour l'administration par voie transmucosale orale d'un principe actif de nicotine.
CA002440713A 2001-03-26 2002-03-22 Forme posologique orale contenant de la nicotine Abandoned CA2440713A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27860601P 2001-03-26 2001-03-26
US60/278,606 2001-03-26
PCT/US2002/008914 WO2002076211A1 (fr) 2001-03-26 2002-03-22 Forme posologique orale contenant de la nicotine

Publications (1)

Publication Number Publication Date
CA2440713A1 true CA2440713A1 (fr) 2002-10-03

Family

ID=23065632

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002440713A Abandoned CA2440713A1 (fr) 2001-03-26 2002-03-22 Forme posologique orale contenant de la nicotine

Country Status (11)

Country Link
EP (1) EP1372392A4 (fr)
JP (1) JP2004525928A (fr)
CN (2) CN101301275A (fr)
AR (1) AR033444A1 (fr)
AU (1) AU2002252470B2 (fr)
BR (1) BR0208382A (fr)
CA (1) CA2440713A1 (fr)
MX (1) MXPA03008762A (fr)
NZ (1) NZ528167A (fr)
PL (1) PL364621A1 (fr)
WO (1) WO2002076211A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
PT1648421T (pt) * 2003-07-24 2017-12-22 Glaxosmithkline Llc Películas de dissolução oral
GB0320854D0 (en) 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
EP1691631A4 (fr) 2003-11-07 2012-09-05 Us Smokeless Tobacco Co Compositions a base de tabac
US8097271B2 (en) * 2004-08-11 2012-01-17 Kraft Foods Global Brands Llc Warming compositions and delivery systems therefor
AU2005284908B2 (en) 2004-09-13 2011-12-08 Morningside Venture Investments Limited Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
WO2008069921A2 (fr) * 2006-12-01 2008-06-12 Cima Labs Inc. Forme de dosage à base de nicotine pour administration par voie orale transmuqueuse
US7718677B2 (en) 2007-04-02 2010-05-18 Parkinson's Institute Methods and compositions for reduction of side effects of therapeutic treatments
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
DE102008012015A1 (de) * 2008-03-01 2009-09-10 Südzucker AG Mannheim/Ochsenfurt Verbesserte Isomalt-haltige Komprimate und Verfahren zu ihrer Herstellung
KR20130008535A (ko) * 2010-02-18 2013-01-22 자틴 바산트 타카르 니코틴을 함유하는 소프트 젤라틴 알약
US20110274628A1 (en) * 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
UA112974C2 (uk) 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
EP2729148A4 (fr) 2011-07-06 2015-04-22 Parkinson S Inst Compositions et méthodes de traitement de symptômes chez des patients atteints de la maladie de parkinson
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9044035B2 (en) * 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
TW201507726A (zh) * 2013-05-10 2015-03-01 Glaxosmithkline Llc 菸鹼菱形錠配製物
CN104132895B (zh) * 2014-07-08 2017-08-25 国家烟草质量监督检验中心 适用于连续流动法测定烟草及烟草制品中总植物碱的缓冲体系
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
EP3267875A4 (fr) 2015-03-12 2018-12-05 Chrono Therapeutics Inc. Système d'entrée d'état de manque et de support
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 経皮薬剤送達の装置及び方法
SE541358C2 (en) * 2017-05-30 2019-08-13 Enorama Pharma Ab Nicotine-containing chewing gum compositions
AU2019279884A1 (en) 2018-05-29 2020-12-10 Morningside Venture Investments Limited Drug delivery methods and systems
AU2021207268A1 (en) * 2020-01-15 2022-09-08 Mcneil Ab Lozenge
US20220313678A1 (en) * 2021-04-06 2022-10-06 Altria Client Services Llc Spray dried nicotine for inclusion in oral products

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
DE19536394A1 (de) * 1995-09-29 1997-04-03 Basf Ag Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
DE19639342C2 (de) * 1996-09-25 1998-07-16 Suedzucker Ag Kaugummi, enthaltend ein Süßungsmittel
US6322806B1 (en) * 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center

Also Published As

Publication number Publication date
JP2004525928A (ja) 2004-08-26
MXPA03008762A (es) 2004-02-18
AR033444A1 (es) 2003-12-17
WO2002076211A1 (fr) 2002-10-03
NZ528167A (en) 2005-04-29
BR0208382A (pt) 2004-06-15
AU2002252470B2 (en) 2008-05-22
EP1372392A4 (fr) 2004-06-23
CN1553771A (zh) 2004-12-08
PL364621A1 (en) 2004-12-13
EP1372392A1 (fr) 2004-01-02
CN101301275A (zh) 2008-11-12

Similar Documents

Publication Publication Date Title
AU2002252470B2 (en) Nicotine-containing oral dosage form
US20040101543A1 (en) Nicotine-containing oral dosage form
AU2003267268B2 (en) Modified release oral dosage form
AU2002252470A1 (en) Nicotine-containing oral dosage form
US20210093563A1 (en) Medicinal delivery system and related methods
CA2652499C (fr) Produit pharmaceutique destine a une administration intrabuccale de nicotine comprenant du trometamol servant d'agent tampon
KR20100017820A (ko) 아미노산으로 완충된 경구 니코틴 제형
CA2685456A1 (fr) Formulation nicotinique orale enrobee, tamponnee aux acides amines
NZ529780A (en) A coated nicotine-containing chewing gum, manufacture and use thereof
AU776019B2 (en) Medicated chewing gum delivery system for nicotine
EP1429770B1 (fr) Nouvelles formulations et leur utilisation
AU2008202048A1 (en) Nicotine-containing oral dosage form
AU2002334523A1 (en) New formulations and use thereof
AU2012241150B2 (en) Medicinal delivery system and related methods
CA2109895A1 (fr) Preparation orale contenant de la nicotine
JUNO et al. PHARMACEUTICAL SCIENCES

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead