CA2437383A1 - Alteration d'un phenotype provoquee par des genes heterologues - Google Patents

Alteration d'un phenotype provoquee par des genes heterologues Download PDF

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Publication number
CA2437383A1
CA2437383A1 CA002437383A CA2437383A CA2437383A1 CA 2437383 A1 CA2437383 A1 CA 2437383A1 CA 002437383 A CA002437383 A CA 002437383A CA 2437383 A CA2437383 A CA 2437383A CA 2437383 A1 CA2437383 A1 CA 2437383A1
Authority
CA
Canada
Prior art keywords
host cell
target protein
heterologous target
protein
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002437383A
Other languages
English (en)
Inventor
Raymond Kim
Fernando J. Rebelo Do Couto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iconix Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2437383A1 publication Critical patent/CA2437383A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Le phénotype d'une séquence cible d'une cellule hôte pouvant être ciblé peut être altéré par fusion de la protéine cible en un partenaire de fusion approprié.
CA002437383A 2001-02-02 2002-02-01 Alteration d'un phenotype provoquee par des genes heterologues Abandoned CA2437383A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26609601P 2001-02-02 2001-02-02
US60/266,096 2001-02-02
PCT/US2002/002857 WO2002063029A1 (fr) 2001-02-02 2002-02-01 Alteration d'un phenotype provoquee par des genes heterologues

Publications (1)

Publication Number Publication Date
CA2437383A1 true CA2437383A1 (fr) 2002-08-15

Family

ID=23013162

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002437383A Abandoned CA2437383A1 (fr) 2001-02-02 2002-02-01 Alteration d'un phenotype provoquee par des genes heterologues

Country Status (2)

Country Link
CA (1) CA2437383A1 (fr)
WO (1) WO2002063029A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10258885A1 (de) * 2002-12-17 2004-07-15 Aventis Pharma Deutschland Gmbh Verfahren zur Generierung eines gentechnisch veränderten Organismus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5871934A (en) * 1993-09-17 1999-02-16 Smithkline Beecham Corporation Screening methods using cytokine suppressive anti-inflammatory drug (CSAID) binding proteins
US7101681B1 (en) * 1997-11-21 2006-09-05 Amgen, Inc. Nuclear hormone receptor drug screens
EP1053358A4 (fr) * 1998-02-10 2002-08-14 Uab Research Foundation Utilisation de l'integrase du vih-1 dans le criblage de medicaments candidats diriges contre le vih-1
AU6062300A (en) * 1999-07-09 2001-01-30 Calgene Llc Enhanced expression of proteins

Also Published As

Publication number Publication date
WO2002063029A1 (fr) 2002-08-15

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Legal Events

Date Code Title Description
FZDE Discontinued