CA2437250A1 - Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente - Google Patents

Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente Download PDF

Info

Publication number
CA2437250A1
CA2437250A1 CA 2437250 CA2437250A CA2437250A1 CA 2437250 A1 CA2437250 A1 CA 2437250A1 CA 2437250 CA2437250 CA 2437250 CA 2437250 A CA2437250 A CA 2437250A CA 2437250 A1 CA2437250 A1 CA 2437250A1
Authority
CA
Canada
Prior art keywords
alginate
cells
islet
islets
des
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2437250
Other languages
English (en)
Inventor
Francois Leblond
Guillaume Jourdan
Jean-Pierre Halle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMS RECH Inc
Original Assignee
IMS RECHERCHE Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMS RECHERCHE Inc filed Critical IMS RECHERCHE Inc
Priority to CA 2437250 priority Critical patent/CA2437250A1/fr
Publication of CA2437250A1 publication Critical patent/CA2437250A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
CA 2437250 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente Abandoned CA2437250A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2437250 CA2437250A1 (fr) 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2437250 CA2437250A1 (fr) 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente

Publications (1)

Publication Number Publication Date
CA2437250A1 true CA2437250A1 (fr) 2005-02-14

Family

ID=34140448

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2437250 Abandoned CA2437250A1 (fr) 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente

Country Status (1)

Country Link
CA (1) CA2437250A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011011962A1 (fr) * 2009-07-31 2011-02-03 清华大学 Méthode de préparation de précurseurs complexes d’organes tissulaires multicouches
US8202701B2 (en) 2004-10-08 2012-06-19 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
US11077289B2 (en) 2013-03-07 2021-08-03 Viacyte, Inc. 3-dimensional large capacity cell encapsulation device assembly
CN113730372A (zh) * 2021-10-15 2021-12-03 中国人民解放军陆军军医大学第二附属医院 一种神经干细胞磷脂膜微囊及其制备方法
CN115737600A (zh) * 2022-11-25 2023-03-07 苏州大学 一种持续产氢生物微球及其制备方法与应用

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202701B2 (en) 2004-10-08 2012-06-19 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
WO2011011962A1 (fr) * 2009-07-31 2011-02-03 清华大学 Méthode de préparation de précurseurs complexes d’organes tissulaires multicouches
US11077289B2 (en) 2013-03-07 2021-08-03 Viacyte, Inc. 3-dimensional large capacity cell encapsulation device assembly
CN113730372A (zh) * 2021-10-15 2021-12-03 中国人民解放军陆军军医大学第二附属医院 一种神经干细胞磷脂膜微囊及其制备方法
CN115737600A (zh) * 2022-11-25 2023-03-07 苏州大学 一种持续产氢生物微球及其制备方法与应用

Similar Documents

Publication Publication Date Title
Chaikof Engineering and material considerations in islet cell transplantation
O'Shea et al. Encapsulation of rat islets of Langerhans prolongs xenograft survival in diabetic mice
ES2227544T3 (es) Celulas secretoras macroencapsuladas.
Pareta et al. Long-term function of islets encapsulated in a redesigned alginate microcapsule construct in omentum pouches of immune-competent diabetic rats
Scott et al. Beyond the red cell: pegylation of other blood cells and tissues
US20070299508A1 (en) Vascularized tissue graft
Haque et al. Combination strategy of multi-layered surface camouflage using hyperbranched polyethylene glycol and immunosuppressive drugs for the prevention of immune reactions against transplanted porcine islets
Samojlik et al. Designing biomaterials for the modulation of allogeneic and autoimmune responses to cellular implants in Type 1 Diabetes
Del Guerra et al. Entrapment of dispersed pancreatic islet cells in CultiSpher‐S macroporous gelatin microcarriers: Preparation, in vitro characterization, and microencapsulation
Rajendran Nair et al. Long-term transplant effects of iPSC-RPE monolayer in immunodeficient RCS rats
Willing et al. Sertoli cell transplants: their use in the treatment of neurodegenerative disease
Komatsu et al. Oxygen transporter for the hypoxic transplantation site
CA2437250A1 (fr) Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente
Mooranian et al. Artificial cell encapsulation for biomaterials and tissue bio-nanoengineering: history, achievements, limitations, and future work for potential clinical applications and transplantation
NO320334B1 (no) Materialblanding av fast agarose-overtrukket agaroseinneholdende eller agarose-kollagenperle inneholdende celler som produserer et diffunderbart biologisk produkt, anvendelser derav, fremgangsmater for fremstilling derav, kondisjonert medium fremstilt ved hjelp av materialblandingen, samt fremgangsmate for a bestemme om en materialblanding er anvendelig i a undertrykke proliferasjon av cancerceller.
Melgar-Lesmes et al. Implantation of healthy matrix-embedded endothelial cells rescues dysfunctional endothelium and ischaemic tissue in liver engraftment
US20020192190A1 (en) Induction of immunological tolerance
Pigeot et al. Orthotopic bone formation by streamlined engineering and devitalization of human hypertrophic cartilage
ES2299417T3 (es) Metodo para producir preparaciones de celulas endocrinas pancreaticas madura e inmaduras, preparacion de las celulas y su utilizacion para el tratamiento de la diabetes mellitus.
Hwang et al. Encapsulation of human islets using a biomimetic self-assembled nanomatrix gel for protection against cellular inflammatory responses
ES2379008T3 (es) Macroperlas que contienen células secretoras que comprenden agarosa Seakem Gold, y sus usos
CA2179341A1 (fr) Methodes pour isoler, enrichir des cultures cellulaires, et accelerer leur maturation
Opara et al. Challenges and perspectives for future considerations in the bioengineering of a bioartificial pancreas
Mietsch et al. “Empowering” Cardiac Cells via Stem Cell Derived Mitochondrial Transplantation-Does Age Matter?
Goldmann et al. Attenuation of transplant arteriosclerosis by oral feeding of major histocompatibility complex encoding chitosan-DNA nanoparticles

Legal Events

Date Code Title Description
FZDE Dead