CA2425829A1 - Proteases - Google Patents

Proteases Download PDF

Info

Publication number
CA2425829A1
CA2425829A1 CA002425829A CA2425829A CA2425829A1 CA 2425829 A1 CA2425829 A1 CA 2425829A1 CA 002425829 A CA002425829 A CA 002425829A CA 2425829 A CA2425829 A CA 2425829A CA 2425829 A1 CA2425829 A1 CA 2425829A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
sequence
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002425829A
Other languages
English (en)
Inventor
Ernestine A. Lee
April J. A. Hafalia
Henry Yue
Preeti G Lal
Monique G Yao
Yan Lu
Narinder K. Chawla
Bridget A. Warren
Dyung Aina M. Lu
Mariah R. Baughn
Angelo M. Delegeane
Neil Burford
Mark L. Borowsky
Sally Lee
Yuming Xu
Jennifer A. Griffin
Deborah A. Kallick
Ameena R. Gandhi
Chandra S. Arvizu
Craig H. Ison
Y. Tom Tang
Yalda Azimzai
Vicki S. Elliott
Anita Swarnakar
Jayalaxmi Ramkumar
Danniel B. Nguyen
Catherine M. Tribouley
Terence P. Lo
Janice Au-Young
Kavitha Thangavelu
Liam Kearney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2425829A1 publication Critical patent/CA2425829A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des protéases humaines (PRTS) et des polynucléotides qui identifient et codent des PRTS; des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes; ainsi que des méthodes de diagnostic, de traitement ou de prévention des maladies associées à une expression aberrante des PRTS.
CA002425829A 2000-10-18 2001-10-18 Proteases Abandoned CA2425829A1 (fr)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US24157300P 2000-10-18 2000-10-18
US60/241,573 2000-10-18
US24364300P 2000-10-25 2000-10-25
US60/243,643 2000-10-25
US24525600P 2000-11-02 2000-11-02
US60/245,256 2000-11-02
US24839500P 2000-11-13 2000-11-13
US60/248,395 2000-11-13
US24982600P 2000-11-16 2000-11-16
US60/249,826 2000-11-16
US25230300P 2000-11-20 2000-11-20
US60/252,303 2000-11-20
US25098100P 2000-12-01 2000-12-01
US60/250,981 2000-12-01
PCT/US2001/051034 WO2002038744A2 (fr) 2000-10-18 2001-10-18 Protéases

Publications (1)

Publication Number Publication Date
CA2425829A1 true CA2425829A1 (fr) 2002-05-16

Family

ID=27569436

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002425829A Abandoned CA2425829A1 (fr) 2000-10-18 2001-10-18 Proteases

Country Status (5)

Country Link
EP (1) EP1387886A2 (fr)
JP (1) JP2004535153A (fr)
AU (1) AU2002239753A1 (fr)
CA (1) CA2425829A1 (fr)
WO (1) WO2002038744A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020260309A1 (fr) 2019-06-24 2020-12-30 Urteste Sp. Z O.O. Nouveau marqueur de diagnostic pour le cancer du pancréas
EP3845664A1 (fr) * 2020-01-02 2021-07-07 Urteste Sp. z o.o. Nouveau marqueur de diagnostic du cancer de la prostate
RU2802849C2 (ru) * 2019-06-24 2023-09-05 Уртесте С.А. Новый маркер для диагностики рака поджелудочной железы

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6683165B1 (en) 1999-04-13 2004-01-27 Genome Therapeutics Corporation Human gene relating to respiratory diseases and obesity
AU2001253512A1 (en) * 2000-04-13 2001-10-30 Genome Therapeutics Corporation Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease
WO2002066643A2 (fr) * 2000-11-13 2002-08-29 Curagen Corporation Proteines, polynucleotides codant pour ces proteines et procedes d'utilisation
DE60126659T2 (de) * 2000-12-25 2007-10-31 Astellas Pharma Inc. Neue protease
US20030022316A1 (en) * 2001-01-24 2003-01-30 Fox Brian A. CUB domain protein zcub3 and materials and methods for making it
WO2002088303A2 (fr) * 2001-04-03 2002-11-07 Bristol-Myers Squibb Company Polynucleotide codant pour une nouvelle cysteine protease de la superfamille calpain, can-12 et leurs variantes
AU2003269880A1 (en) * 2002-05-21 2003-12-22 Dendreon Corporation Nucleic acid molecules encoding a transmembrane serine protease 12, the encoded polypeptides and methods based thereon
WO2004011654A1 (fr) * 2002-07-31 2004-02-05 Yamanouchi Pharmaceutical Co., Ltd. Serine protease
ES2773766T3 (es) 2008-12-19 2020-07-14 Baxalta GmbH Inhibidores de TFPI y métodos de uso

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0647138A4 (fr) * 1993-02-05 1996-03-06 Daratech Pty Ltd Polypeptides pouvant etre obtenus a partir d'especes de fasciola, et vaccins, procedes de traitement, et sequences d'adn de ces polypeptides.
US6544767B1 (en) * 1994-10-27 2003-04-08 Axys Pharmaceuticals, Inc. Cathespin O2 protease

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020260309A1 (fr) 2019-06-24 2020-12-30 Urteste Sp. Z O.O. Nouveau marqueur de diagnostic pour le cancer du pancréas
RU2802849C2 (ru) * 2019-06-24 2023-09-05 Уртесте С.А. Новый маркер для диагностики рака поджелудочной железы
EP3845664A1 (fr) * 2020-01-02 2021-07-07 Urteste Sp. z o.o. Nouveau marqueur de diagnostic du cancer de la prostate

Also Published As

Publication number Publication date
WO2002038744A2 (fr) 2002-05-16
JP2004535153A (ja) 2004-11-25
WO2002038744A3 (fr) 2003-11-20
EP1387886A2 (fr) 2004-02-11
AU2002239753A1 (en) 2002-05-21

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Legal Events

Date Code Title Description
FZDE Dead