CA2434953A1 - Molecules de modification et de maintenance proteiques - Google Patents

Molecules de modification et de maintenance proteiques Download PDF

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Publication number
CA2434953A1
CA2434953A1 CA002434953A CA2434953A CA2434953A1 CA 2434953 A1 CA2434953 A1 CA 2434953A1 CA 002434953 A CA002434953 A CA 002434953A CA 2434953 A CA2434953 A CA 2434953A CA 2434953 A1 CA2434953 A1 CA 2434953A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
sequence
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002434953A
Other languages
English (en)
Inventor
Bridget A. Warren
Cynthia D. Honchell
Yan Lu
Narinder K. Chawla
Neil Burford
Angelo M. Delegeane
Ameena R. Gandhi
Mariah R. Baughn
Jennifer A. Griffin
Kimberly J. Gietzen
Dyung Aina M. Lu
Craig H. Ison
Jayalaxmi Ramkumar
Y. Tom Tang
Preeti G. Lal
Mark L. Borowski
Brendan M. Duggan
April J. A. Hafalia
Chandra Arvizu
Kavitha Thangavelu
Monique G. Yao
Vicki S. Elliott
Li Ding
Henry Yue
Sally Lee
Anita Swarnakar
Uyen K. Tran
Yuming Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2434953A1 publication Critical patent/CA2434953A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne des molécules de maintenance et de modification protéiques humaines (PMMM) et des polynucléotides qui identifient et codent ces PMMM. Cette invention a également trait à des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes, ainsi qu'à des méthodes de diagnostic, de traitement ou de prévention de troubles liés à l'expression aberrante des PMMM.
CA002434953A 2001-01-31 2002-01-30 Molecules de modification et de maintenance proteiques Abandoned CA2434953A1 (fr)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US26570501P 2001-01-31 2001-01-31
US60/265,705 2001-01-31
US26676201P 2001-02-05 2001-02-05
US60/266,762 2001-02-05
US26958101P 2001-02-16 2001-02-16
US60/269,581 2001-02-16
US27119801P 2001-02-23 2001-02-23
US60/271,198 2001-02-23
US27281301P 2001-03-01 2001-03-01
US60/272,813 2001-03-01
US27558601P 2001-03-13 2001-03-13
US60/275,586 2001-03-13
US27850501P 2001-03-23 2001-03-23
US60/278,505 2001-03-23
US28053901P 2001-03-30 2001-03-30
US60/280,539 2001-03-30
PCT/US2002/002813 WO2002060942A2 (fr) 2001-01-31 2002-01-30 Molecules de modification et de maintenance proteiques

Publications (1)

Publication Number Publication Date
CA2434953A1 true CA2434953A1 (fr) 2002-08-08

Family

ID=27575307

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002434953A Abandoned CA2434953A1 (fr) 2001-01-31 2002-01-30 Molecules de modification et de maintenance proteiques

Country Status (5)

Country Link
EP (1) EP1356028A2 (fr)
JP (1) JP2005503108A (fr)
AU (1) AU2002253883A1 (fr)
CA (1) CA2434953A1 (fr)
WO (1) WO2002060942A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE20010121A1 (en) * 2000-02-18 2002-12-11 Hoffmann La Roche Novel Metalloproteases having Thrombospondin Domains and Nucleic Acid Compositions encoding the same
WO2002050277A2 (fr) * 2000-12-21 2002-06-27 Curagen Corporation Proteines et acides nucleiques codant pour celles-ci
AU2002304249A1 (en) 2001-06-11 2002-12-23 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same
US7125701B2 (en) 2001-07-27 2006-10-24 Wyeth Aggrecanase molecules
EP2228443A1 (fr) * 2001-08-30 2010-09-15 ARCA biopharma, Inc. Méthodes et matériaux concernant les polypetide similaire au Stem Cell Growth Factor et les polynucléotides les codant
US7439332B2 (en) 2002-04-26 2008-10-21 Kirin Pharma Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem or progenitor cells
EP1673475B1 (fr) * 2003-10-10 2010-04-28 Deutsches Krebsforschungszentrum Compositions pour le diagnostic et le traitement de maladies associees a l'expression aberrante des futrins (r-spondins) et/ou wnt
CA2587979A1 (fr) * 2004-11-19 2006-05-26 Oy Jurilab Ltd Procede et kit de detection d'un risque d'hypertension arterielle essentielle
PL2081586T5 (pl) 2006-10-20 2019-04-30 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Rspondyny jako modulatory angiogenezy i waskulogenezy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1297158A2 (fr) * 2000-06-21 2003-04-02 Bayer Aktiengesellschaft Regulation d'une enzyme de type serine protease 1 d'eosinophile humain
AU2001271427A1 (en) * 2000-06-26 2002-01-08 Sugen, Inc. Novel proteases

Also Published As

Publication number Publication date
WO2002060942A3 (fr) 2003-07-24
JP2005503108A (ja) 2005-02-03
WO2002060942A2 (fr) 2002-08-08
EP1356028A2 (fr) 2003-10-29
AU2002253883A1 (en) 2002-08-12

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Legal Events

Date Code Title Description
FZDE Dead