CA2418506A1 - Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases - Google Patents

Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases Download PDF

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Publication number
CA2418506A1
CA2418506A1 CA002418506A CA2418506A CA2418506A1 CA 2418506 A1 CA2418506 A1 CA 2418506A1 CA 002418506 A CA002418506 A CA 002418506A CA 2418506 A CA2418506 A CA 2418506A CA 2418506 A1 CA2418506 A1 CA 2418506A1
Authority
CA
Canada
Prior art keywords
positively influence
airway diseases
identifying substances
chronic inflammatory
inflammatory conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002418506A
Other languages
French (fr)
Other versions
CA2418506C (en
Inventor
Birgit Jung
Norbert Kraut
Stefan Muller
Barbara Kistler
Peter Seither
Karsten Quast
Andreas Weith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2418506A1 publication Critical patent/CA2418506A1/en
Application granted granted Critical
Publication of CA2418506C publication Critical patent/CA2418506C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The present invention relates to substances which modulate receptors involved in inflammatory processes and whose modulated functions positively influence inflammatory diseases.
CA002418506A 2000-09-01 2001-08-23 Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases Expired - Fee Related CA2418506C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0021484.1A GB0021484D0 (en) 2000-09-01 2000-09-01 Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases
GB0021484.1 2000-09-01
PCT/EP2001/009727 WO2002018938A1 (en) 2000-09-01 2001-08-23 Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases

Publications (2)

Publication Number Publication Date
CA2418506A1 true CA2418506A1 (en) 2002-03-07
CA2418506C CA2418506C (en) 2009-04-28

Family

ID=9898663

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002418506A Expired - Fee Related CA2418506C (en) 2000-09-01 2001-08-23 Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases

Country Status (7)

Country Link
EP (1) EP1315963A1 (en)
JP (1) JP2004507262A (en)
AU (1) AU2001282118A1 (en)
CA (1) CA2418506C (en)
GB (1) GB0021484D0 (en)
MX (1) MXPA03001506A (en)
WO (1) WO2002018938A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1364017A2 (en) * 2000-08-18 2003-11-26 Novartis AG Inflammation related g-protein coupled receptor
WO2003023007A2 (en) 2001-09-07 2003-03-20 Bristol-Myers Squibb Company Polynucleotide encoding a novel human g-protein coupled receptor, hgprbmy39
US6902902B2 (en) 2001-11-27 2005-06-07 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
JP2005536187A (en) * 2002-04-03 2005-12-02 バイエル・ヘルスケア・アクチェンゲゼルシャフト Diagnosis and treatment of diseases associated with N-formyl peptide receptor-like 1 (FPRL1)
US7189524B1 (en) 2002-11-25 2007-03-13 Amgen, Inc. Receptor ligands and methods of modulating receptors
EP1597586A2 (en) * 2003-02-13 2005-11-23 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with hm74
EP1603585A2 (en) 2003-03-14 2005-12-14 Bristol-Myers Squibb Company Polynucleotide encoding a novel human g-protein coupled receptor variant of hm74, hgprbmy74
RU2006133540A (en) * 2004-02-20 2008-03-27 Авентис Фармасьютикалз Инк. (Us) FUROSEMIDE MODULATORS NM74
RU2006133539A (en) * 2004-02-20 2008-03-27 Авентис Фармасьютикалз Инк. (Us) OXIDE DECAGIDRONAFTALINE HM74 MODULATORS
EP1960792A2 (en) * 2005-12-07 2008-08-27 Boehringer Ingelheim International Gmbh Treatment and diagnostics of inflammatory diseases
JP6151129B2 (en) * 2013-08-19 2017-06-21 テルモ株式会社 Fibrotic agent
JP6210794B2 (en) * 2013-08-19 2017-10-11 テルモ株式会社 Fibrotic agent
AU2018308364C1 (en) 2017-07-26 2023-02-16 Forty Seven, Inc. Anti-SIRP-alpha antibodies and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648344A (en) * 1990-07-30 1997-07-15 Glycomed Incorporated Methods of treating inflammation using selection binding compounds
ATE197646T1 (en) * 1990-08-06 2000-12-15 Chiron Corp METHOD FOR DETECTING CYTOKINE CONVERTASE INHIBITORS
WO1994025570A1 (en) * 1993-04-23 1994-11-10 Sloan-Kettering Institute For Cancer Research Method for screening for targets for anti-inflammatory or anti-allergic agents
US6160088A (en) * 1998-07-29 2000-12-12 Sloan-Kettering Institute For Cancer KDEL receptor inhibitors
WO2000031261A2 (en) * 1998-11-25 2000-06-02 Cadus Pharmaceutical Corporation Methods and compositions for identifying effectors of the formyl peptide receptor like-1 (fprl-1) receptor
EP1137947B1 (en) * 1998-12-11 2005-10-19 Children's Hospital Medical Center Method for determining asthma susceptibility
EP1364017A2 (en) * 2000-08-18 2003-11-26 Novartis AG Inflammation related g-protein coupled receptor

Also Published As

Publication number Publication date
EP1315963A1 (en) 2003-06-04
CA2418506C (en) 2009-04-28
GB0021484D0 (en) 2000-10-18
MXPA03001506A (en) 2003-06-09
AU2001282118A1 (en) 2002-03-13
JP2004507262A (en) 2004-03-11
WO2002018938A1 (en) 2002-03-07

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