CA2416952A1 - Sondes combinatoires et utilisations associees - Google Patents

Sondes combinatoires et utilisations associees Download PDF

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Publication number
CA2416952A1
CA2416952A1 CA002416952A CA2416952A CA2416952A1 CA 2416952 A1 CA2416952 A1 CA 2416952A1 CA 002416952 A CA002416952 A CA 002416952A CA 2416952 A CA2416952 A CA 2416952A CA 2416952 A1 CA2416952 A1 CA 2416952A1
Authority
CA
Canada
Prior art keywords
target
probes
sequences
polynucleotides
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002416952A
Other languages
English (en)
Inventor
Mark John Gibbs
Adrian John Gibbs
Roger William Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Australian National University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPQ9026A external-priority patent/AUPQ902600A0/en
Priority claimed from AUPQ9483A external-priority patent/AUPQ948300A0/en
Application filed by Individual filed Critical Individual
Publication of CA2416952A1 publication Critical patent/CA2416952A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression

Abstract

L'invention concerne un ensemble de sondes oligonucléotidiques ainsi qu'un procédé de détection de plusieurs polynucléotides cibles, différents. Cet ensemble comprend une collection de différentes sondes ubiquistes, chacune capable de s'hybrider à une séquence cible partagée par au moins deux polynucléotides cibles. Au moins l'un des polynucléotides cibles comprend au moins une séquence cible partagée avec au moins un autre polynucléotide cible. Une combinaison de sondes ubiquistes est capable de s'hybrider à des séquences cibles dudit polynucléotide cible, au moins, cette combinaison déterminée de sondes apportant la spécificité de détection du polynucléotide cible. L'invention concerne encore des procédés d'identification d'un ensemble de séquences cibles, servant à désigner l'ensemble de sondes oligonucléotidiques de l'invention.
CA002416952A 2000-07-27 2001-07-27 Sondes combinatoires et utilisations associees Abandoned CA2416952A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
AUPQ9026 2000-07-27
AUPQ9026A AUPQ902600A0 (en) 2000-07-27 2000-07-27 Combinatorial probes and uses therefor
AUPQ9483 2000-08-17
AUPQ9483A AUPQ948300A0 (en) 2000-08-17 2000-08-17 Combinatorial probes and uses therefor
US22621200P 2000-08-18 2000-08-18
US60/226,212 2000-08-18
PCT/AU2001/000931 WO2002010443A1 (fr) 2000-07-27 2001-07-27 Sondes combinatoires et utilisations associees

Publications (1)

Publication Number Publication Date
CA2416952A1 true CA2416952A1 (fr) 2002-02-07

Family

ID=27158234

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002416952A Abandoned CA2416952A1 (fr) 2000-07-27 2001-07-27 Sondes combinatoires et utilisations associees

Country Status (5)

Country Link
EP (1) EP1322780A4 (fr)
JP (1) JP2004504068A (fr)
CA (1) CA2416952A1 (fr)
NZ (1) NZ523715A (fr)
WO (1) WO2002010443A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2004079627A1 (ja) * 2003-03-07 2006-06-08 株式会社ダイナコム 遺伝子を同定するための作用要素の選択方法
JP2005190427A (ja) 2003-12-26 2005-07-14 Canon Inc 配列を同定するための変異要素のセット抽出方法
US9957569B2 (en) 2005-09-12 2018-05-01 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
CA2814598A1 (fr) 2005-09-12 2007-03-22 The Regents Of The University Of Michigan Fusion geniques recurrentes dans le cancer de la prostate
JP5433572B2 (ja) 2007-07-06 2014-03-05 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Ｍｉｐｏｌ１−ｅｔｖ１遺伝子再編成
US20120015839A1 (en) * 2009-01-09 2012-01-19 The Regents Of The University Of Michigan Recurrent gene fusions in cancer
EP2478120B1 (fr) 2009-09-17 2015-09-02 The Regents Of The University Of Michigan Fusions de gène récurrentes dans le cancer de la prostate
US10240194B2 (en) * 2010-05-13 2019-03-26 Gen9, Inc. Methods for nucleotide sequencing and high fidelity polynucleotide synthesis
US8945556B2 (en) 2010-11-19 2015-02-03 The Regents Of The University Of Michigan RAF gene fusions
JP6321318B2 (ja) * 2012-09-14 2018-05-09 日本碍子株式会社 標的核酸の検出方法
US9409139B2 (en) 2013-08-05 2016-08-09 Twist Bioscience Corporation De novo synthesized gene libraries
CA2975852A1 (fr) 2015-02-04 2016-08-11 Twist Bioscience Corporation Procedes et dispositifs pour assemblage de novo d'acide oligonucleique
WO2016126987A1 (fr) 2015-02-04 2016-08-11 Twist Bioscience Corporation Compositions et méthodes d'assemblage de gène synthétique
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
AU2016324296A1 (en) 2015-09-18 2018-04-12 Twist Bioscience Corporation Oligonucleic acid variant libraries and synthesis thereof
US11512347B2 (en) 2015-09-22 2022-11-29 Twist Bioscience Corporation Flexible substrates for nucleic acid synthesis
CN115920796A (zh) 2015-12-01 2023-04-07 特韦斯特生物科学公司 功能化表面及其制备
US11728009B2 (en) * 2016-03-01 2023-08-15 Fusion Genomics Corporation System and process for data-driven design, synthesis, and application of molecular probes
CA3034769A1 (fr) 2016-08-22 2018-03-01 Twist Bioscience Corporation Banques d'acides nucleiques synthetises de novo
WO2018057526A2 (fr) 2016-09-21 2018-03-29 Twist Bioscience Corporation Stockage de données reposant sur un acide nucléique
US10907274B2 (en) 2016-12-16 2021-02-02 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
CN110892485B (zh) 2017-02-22 2024-03-22 特韦斯特生物科学公司 基于核酸的数据存储
EP3595674A4 (fr) 2017-03-15 2020-12-16 Twist Bioscience Corporation Banques de variants de la synapse immunologique et leur synthèse
WO2018231864A1 (fr) 2017-06-12 2018-12-20 Twist Bioscience Corporation Méthodes d'assemblage d'acides nucléiques continus
US10696965B2 (en) 2017-06-12 2020-06-30 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
EP3681906A4 (fr) 2017-09-11 2021-06-09 Twist Bioscience Corporation Protéines se liant au gpcr et leurs procédés de synthèse
GB2583590A (en) 2017-10-20 2020-11-04 Twist Bioscience Corp Heated nanowells for polynucleotide synthesis
KR20200106067A (ko) 2018-01-04 2020-09-10 트위스트 바이오사이언스 코포레이션 Dna 기반 디지털 정보 저장
SG11202011467RA (en) 2018-05-18 2020-12-30 Twist Bioscience Corp Polynucleotides, reagents, and methods for nucleic acid hybridization
KR20210143766A (ko) 2019-02-26 2021-11-29 트위스트 바이오사이언스 코포레이션 Glp1 수용체에 대한 변이체 핵산 라이브러리
WO2020176680A1 (fr) 2019-02-26 2020-09-03 Twist Bioscience Corporation Banques d'acides nucléiques variants pour l'optimisation d'anticorps
CA3144644A1 (fr) 2019-06-21 2020-12-24 Twist Bioscience Corporation Assemblage de sequences d'acide nucleique base sur des code-barres

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541308A (en) * 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
EP0769068B1 (fr) * 1994-06-24 2005-10-12 Innogenetics N.V. Detection, identification et differentiation simultanees de taxa d'eubacteriales a l'aide d'une technique d'hybridation
US5683881A (en) * 1995-10-20 1997-11-04 Biota Corp. Method of identifying sequence in a nucleic acid target using interactive sequencing by hybridization
DE19616750A1 (de) * 1996-04-26 1997-11-06 Newlab Diagnostic Systems Gmbh Verfahren zum Nachweis von Mikroorganismen in Gemischen
AU1337099A (en) * 1997-10-29 1999-05-17 Mira Diagnostica Gmbh Method for identifying micro-organisms
US6306643B1 (en) * 1998-08-24 2001-10-23 Affymetrix, Inc. Methods of using an array of pooled probes in genetic analysis
EP1144684B1 (fr) * 1999-01-06 2009-08-19 Callida Genomics, Inc. Sequencage par hybridation, ameliore, utilisant des groupes de sondes

Also Published As

Publication number Publication date
WO2002010443A1 (fr) 2002-02-07
JP2004504068A (ja) 2004-02-12
EP1322780A4 (fr) 2005-08-03
EP1322780A1 (fr) 2003-07-02
NZ523715A (en) 2004-07-30

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued