CA2413081A1 - Agonist versus antagonist binding to g protein-coupled receptors - Google Patents

Agonist versus antagonist binding to g protein-coupled receptors Download PDF

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Publication number
CA2413081A1
CA2413081A1 CA002413081A CA2413081A CA2413081A1 CA 2413081 A1 CA2413081 A1 CA 2413081A1 CA 002413081 A CA002413081 A CA 002413081A CA 2413081 A CA2413081 A CA 2413081A CA 2413081 A1 CA2413081 A1 CA 2413081A1
Authority
CA
Canada
Prior art keywords
receptor
agonist
ligand
binding
antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002413081A
Other languages
English (en)
French (fr)
Inventor
Scott Cowell
Zdzislaw Salamon
Victor J. Hruby
Gordon Tollin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arizona
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2413081A1 publication Critical patent/CA2413081A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA002413081A 2000-06-22 2001-06-21 Agonist versus antagonist binding to g protein-coupled receptors Abandoned CA2413081A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21357500P 2000-06-22 2000-06-22
US60/213,575 2000-06-22
PCT/US2001/019871 WO2001098747A2 (en) 2000-06-22 2001-06-21 Agonist versus antagonist binding to g protein-coupled receptors

Publications (1)

Publication Number Publication Date
CA2413081A1 true CA2413081A1 (en) 2001-12-27

Family

ID=22795635

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002413081A Abandoned CA2413081A1 (en) 2000-06-22 2001-06-21 Agonist versus antagonist binding to g protein-coupled receptors

Country Status (5)

Country Link
EP (1) EP1295120A2 (ja)
JP (1) JP2004507716A (ja)
AU (1) AU2001270046A1 (ja)
CA (1) CA2413081A1 (ja)
WO (1) WO2001098747A2 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030006192A1 (en) * 1998-02-23 2003-01-09 Irving Wainer Immobilized G-protein coupled receptors on liquid chromatography stationary phases and use thereof for on-line screening
US7678539B2 (en) 2000-08-10 2010-03-16 Corning Incorporated Arrays of biological membranes and methods and use thereof
US20160334395A1 (en) * 2014-01-21 2016-11-17 Nanyang Technological University Hydration layer/lipid bilayer structures

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0709809B1 (en) * 1994-10-28 2002-01-23 Oki Electric Industry Company, Limited Image encoding and decoding method and apparatus using edge synthesis and inverse wavelet transform

Also Published As

Publication number Publication date
EP1295120A2 (en) 2003-03-26
AU2001270046A1 (en) 2002-01-02
WO2001098747A3 (en) 2002-04-11
JP2004507716A (ja) 2004-03-11
WO2001098747A2 (en) 2001-12-27

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Legal Events

Date Code Title Description
FZDE Discontinued