CA2412124A1 - Facteur de croissance 2 de tissu conjonctif - Google Patents

Facteur de croissance 2 de tissu conjonctif Download PDF

Info

Publication number
CA2412124A1
CA2412124A1 CA002412124A CA2412124A CA2412124A1 CA 2412124 A1 CA2412124 A1 CA 2412124A1 CA 002412124 A CA002412124 A CA 002412124A CA 2412124 A CA2412124 A CA 2412124A CA 2412124 A1 CA2412124 A1 CA 2412124A1
Authority
CA
Canada
Prior art keywords
ctgf
polypeptide
antibodies
antibody
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002412124A
Other languages
English (en)
Inventor
Haodong Li
Mark D. Adams
Valerie Calenda
Virginie Fataccioli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Human Genome Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2412124A1 publication Critical patent/CA2412124A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un polypeptide CTGH-2 humain et l'ADN (ARN) codant ce polypeptide, une méthode de production d'un tel polypeptide au moyen de techniques de recombinaison, ainsi que des anticorps et des antagonistes/des inhibiteurs de ce polypeptide. Cette invention a également trait à des méthodes d'utilisation du polypeptide à des fins thérapeutiques pour stimuler l'angiogenèse, améliorer la réparation de tissus conjonctifs et de soutien, promouvoir l'attache, la fixation et la stabilisation des implants, et améliorer la guérison des blessures. Ladite invention concerne aussi des dosages diagnostiques permettant d'identifier des mutations dans une séquence d'acide nucléique codant un polypeptide susmentionné et de détecter des niveaux modifiés dudit polypeptide.
CA002412124A 2000-07-11 2001-07-11 Facteur de croissance 2 de tissu conjonctif Abandoned CA2412124A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21740200P 2000-07-11 2000-07-11
US60/217,402 2000-07-11
US29164201P 2001-05-18 2001-05-18
US60/291,642 2001-05-18
PCT/US2001/021799 WO2002004480A2 (fr) 2000-07-11 2001-07-11 Facteur de croissance 2 de tissu conjonctif

Publications (1)

Publication Number Publication Date
CA2412124A1 true CA2412124A1 (fr) 2002-01-17

Family

ID=26911905

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002412124A Abandoned CA2412124A1 (fr) 2000-07-11 2001-07-11 Facteur de croissance 2 de tissu conjonctif

Country Status (4)

Country Link
EP (1) EP1373299A4 (fr)
AU (1) AU2001276868A1 (fr)
CA (1) CA2412124A1 (fr)
WO (1) WO2002004480A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005508133A (ja) 2001-01-11 2005-03-31 キュラジェン コーポレイション タンパク質およびそれをコードする核酸
TW201102086A (en) 2009-06-04 2011-01-16 Hoffmann La Roche Antibodies against human CCN1 and uses thereof
WO2011107590A1 (fr) * 2010-03-04 2011-09-09 Wolfgang Poller Cnn1 (cyr61) dans le traitement prophylactique et thérapeutique d'une maladie inflammatoire
KR102586165B1 (ko) * 2019-10-02 2023-10-10 아주대학교산학협력단 생체 조직 접착성 및 결합력이 증가된 조직 유합제 조성물 및 이의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770209A (en) * 1991-08-30 1998-06-23 University Of South Florida Acceleration of wound healing using connective tissue growth factor
US5837258A (en) * 1991-08-30 1998-11-17 University Of South Florida Induction of tissue, bone or cartilage formation using connective tissue growth factor
US5792453A (en) * 1995-02-28 1998-08-11 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
AU733382B2 (en) * 1996-03-15 2001-05-10 Munin Corporation Extracellular matrix signalling molecules
US5944710A (en) * 1996-06-24 1999-08-31 Genetronics, Inc. Electroporation-mediated intravascular delivery
CA2354422A1 (fr) * 1998-12-14 2000-06-22 University Of Miami Fragments de facteur de croissance du tissu conjonctif, et methodes et utilisations correspondantes

Also Published As

Publication number Publication date
WO2002004480A3 (fr) 2003-10-16
EP1373299A4 (fr) 2005-01-19
AU2001276868A1 (en) 2002-01-21
EP1373299A2 (fr) 2004-01-02
WO2002004480A2 (fr) 2002-01-17

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Legal Events

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