CA2410665C - Modified bovine adenovirus having altered tropism - Google Patents
Modified bovine adenovirus having altered tropism Download PDFInfo
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- CA2410665C CA2410665C CA2410665A CA2410665A CA2410665C CA 2410665 C CA2410665 C CA 2410665C CA 2410665 A CA2410665 A CA 2410665A CA 2410665 A CA2410665 A CA 2410665A CA 2410665 C CA2410665 C CA 2410665C
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- adenovirus
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
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- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
- C12N2810/6018—Adenoviridae
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- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20867800P | 2000-05-31 | 2000-05-31 | |
| US60/208,678 | 2000-05-31 | ||
| PCT/CA2001/000798 WO2001092547A2 (en) | 2000-05-31 | 2001-05-31 | Modified bovine adenovirus having altered tropism |
Publications (2)
| Publication Number | Publication Date |
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| CA2410665A1 CA2410665A1 (en) | 2001-12-06 |
| CA2410665C true CA2410665C (en) | 2017-11-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2410665A Expired - Lifetime CA2410665C (en) | 2000-05-31 | 2001-05-31 | Modified bovine adenovirus having altered tropism |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6849446B2 (https=) |
| EP (1) | EP1285079A2 (https=) |
| JP (1) | JP2003534805A (https=) |
| AU (2) | AU2001263689B2 (https=) |
| CA (1) | CA2410665C (https=) |
| WO (1) | WO2001092547A2 (https=) |
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| US5820868A (en) | 1993-12-09 | 1998-10-13 | Veterinary Infectious Disease Organization | Recombinant protein production in bovine adenovirus expression vector system |
| US20030220284A1 (en) * | 2002-02-22 | 2003-11-27 | Patricia Yotnda | Delivery of adenoviral DNA in a liposomal formulation for treatment of disease |
| FR2842823A1 (fr) * | 2002-07-25 | 2004-01-30 | Inst Nat Sante Rech Med | Adenovirus modifies pour le ciblage des lymphocytes b |
| WO2004108755A2 (en) * | 2003-06-10 | 2004-12-16 | University Of Saskatchewan | Chimeric adenovirus capsid proteins |
| AU2005309485A1 (en) * | 2004-11-24 | 2006-06-01 | Nanovector Limited | Viral vectors |
| WO2008012682A2 (en) | 2006-07-28 | 2008-01-31 | Commonwealth Scientific And Industrial Research O Rganisation | Methods and compositions for increasing tissue tropism of recombinant adenoviral vectors |
| KR100812636B1 (ko) | 2006-10-24 | 2008-03-13 | 주식회사 단바이오텍 | 항원 결정기를 포함하는 재조합 개 아데노바이러스 섬유단백질 및 이에 대한 항체 |
| CN102549152B (zh) * | 2009-07-31 | 2015-11-25 | 帕克斯瓦克斯股份有限公司 | 基于腺病毒的载体 |
| AU2014236207B2 (en) | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| KR20250081944A (ko) | 2014-09-24 | 2025-06-05 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP4155411A1 (en) | 2016-02-23 | 2023-03-29 | Salk Institute for Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| CN112105630A (zh) * | 2018-02-15 | 2020-12-18 | T·比约尔克隆德 | 经修饰的病毒衣壳 |
| MX2020010499A (es) | 2018-04-09 | 2020-10-28 | Salk Inst For Biological Studi | Composiciones de adenovirus oncoliticas con propiedades aumentadas de replicacion. |
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| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| ZA858044B (en) | 1984-11-01 | 1987-05-27 | American Home Prod | Oral vaccines |
| CA1319101C (en) | 1986-09-03 | 1993-06-15 | Marta Iris Sabara | Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules |
| US5151267A (en) | 1988-07-15 | 1992-09-29 | University Of Saskatchewan | Bovine herpesvirus type 1 polypeptides and vaccines |
| FR2642767B1 (fr) | 1989-01-19 | 1993-10-01 | Transgene Sa | Vecteurs d'expression de proteines heterologues dans les cellules eucaryotes, lignees cellulaires obtenues et procede pour leur preparation |
| ES2091221T3 (es) | 1989-03-24 | 1996-11-01 | Wistar Inst | Vacuna de citomegalovirus recombinante. |
| GB9001766D0 (en) | 1990-01-25 | 1990-03-28 | Univ Court Of The University O | Vaccines |
| US5820868A (en) * | 1993-12-09 | 1998-10-13 | Veterinary Infectious Disease Organization | Recombinant protein production in bovine adenovirus expression vector system |
| US5559099A (en) | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| US6127525A (en) | 1995-02-21 | 2000-10-03 | Cornell Research Foundation, Inc. | Chimeric adenoviral coat protein and methods of using same |
| AUPN477695A0 (en) | 1995-08-14 | 1995-09-07 | Commonwealth Scientific And Industrial Research Organisation | Gene therapy |
| JP3420586B2 (ja) * | 1995-11-28 | 2003-06-23 | ジェンベク、インコーポレイティッド | 細胞への遣伝子導入のためのベクターおよび方法 |
| EP0866721A4 (en) | 1995-12-08 | 2003-06-04 | Univ Alabama Birmingham Res Fo | TARGET ADENOVIRAL VECTORS |
| NZ334827A (en) * | 1996-09-25 | 2001-02-23 | Scripps Research Inst | High-capacity adenoviral vectors suitable for adenoviral-based gene therapy |
| US5877011A (en) | 1996-11-20 | 1999-03-02 | Genzyme Corporation | Chimeric adenoviral vectors |
| FR2761689B1 (fr) * | 1997-04-02 | 1999-06-25 | Transgene Sa | Fibre adenovirale modifiee et adenovirus cibles |
| EP0998576B1 (en) * | 1997-06-23 | 2007-10-31 | The University of Saskatchewan | Method for producing a recombinant bovine adenovirus vector |
| CA2317941A1 (en) * | 1998-01-16 | 1999-07-22 | Genzyme Corporation | Adenoviral vectors with modified capsid proteins |
| IL137681A0 (en) | 1998-02-06 | 2001-10-31 | Uab Research Foundation | Adenovirus vector containing a heterologous peptide epitope in the hi loop of the fiber knob |
| IL137730A0 (en) | 1998-02-17 | 2001-10-31 | Uab Research Foundation | Modified adenovirus containing a fiber replacement protein |
| US5922576A (en) | 1998-02-27 | 1999-07-13 | The John Hopkins University | Simplified system for generating recombinant adenoviruses |
| US20030017138A1 (en) | 1998-07-08 | 2003-01-23 | Menzo Havenga | Chimeric adenoviruses |
| EP1112372A1 (en) * | 1998-09-11 | 2001-07-04 | Genvec, Inc. | Alternatively targeted adenovirus |
| JP2002528128A (ja) * | 1998-11-02 | 2002-09-03 | ユニバーシティ オブ サスカチュワン | 組換えアデノウイルスベクターの増殖のためのアデノウイルス必須機能を発現するウシ細胞 |
| IL133032A (en) | 1998-11-20 | 2007-06-03 | Introgene Bv | Adenoviral gene delivery vectors provided with a tissue tropism for smooth muscle cells and /or endothelial cells |
| ATE519855T1 (de) | 1999-05-17 | 2011-08-15 | Crucell Holland Bv | Rekombinantes adenovirus des serotyps ad11 |
| CA2378324A1 (en) | 1999-07-06 | 2001-01-11 | Leif Lindholm | Recombinant adenovirus |
| WO2001021216A1 (en) | 1999-09-24 | 2001-03-29 | The Uab Research Foundation | Capsid-modified recombinant adenovirus and methods of use |
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| AU6368901A (en) | 2001-12-11 |
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| US20020034519A1 (en) | 2002-03-21 |
| US6849446B2 (en) | 2005-02-01 |
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