CA2407777A1 - Nouveaux composes spiro¬2.4|heptane amino carboxy et derives associes - Google Patents

Nouveaux composes spiro¬2.4|heptane amino carboxy et derives associes Download PDF

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Publication number
CA2407777A1
CA2407777A1 CA002407777A CA2407777A CA2407777A1 CA 2407777 A1 CA2407777 A1 CA 2407777A1 CA 002407777 A CA002407777 A CA 002407777A CA 2407777 A CA2407777 A CA 2407777A CA 2407777 A1 CA2407777 A1 CA 2407777A1
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Canada
Prior art keywords
compound
group
formula
groups
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002407777A
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English (en)
Inventor
Kenneth Curry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002407777A priority Critical patent/CA2407777A1/fr
Priority claimed from PCT/CA2001/000650 external-priority patent/WO2001085669A1/fr
Publication of CA2407777A1 publication Critical patent/CA2407777A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/50—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/93—Spiro compounds
    • C07C2603/94—Spiro compounds containing "free" spiro atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention se rapporte à de nouveaux composés spiro[2.4]heptane amino carboxy et à des dérivés de ces composés. L'invention se rapporte également à un procédé de préparation de composés représentés par la formule (I), et à des compositions pharmaceutiques comportant ces composés. Ces nouveaux composés jouent le rôle de modulateurs des récepteurs du glutamate métabotropique et, en tant que tels, s'avèrent utiles pour le traitement des maladies du système nerveux central liées au système récepteur du glutamate métabotropique.
CA002407777A 2000-05-11 2001-05-11 Nouveaux composes spiro¬2.4|heptane amino carboxy et derives associes Abandoned CA2407777A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002407777A CA2407777A1 (fr) 2000-05-11 2001-05-11 Nouveaux composes spiro¬2.4|heptane amino carboxy et derives associes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA2,308,536 2000-05-11
CA2308536 2000-05-11
CA002407777A CA2407777A1 (fr) 2000-05-11 2001-05-11 Nouveaux composes spiro¬2.4|heptane amino carboxy et derives associes
PCT/CA2001/000650 WO2001085669A1 (fr) 2000-05-11 2001-05-11 Nouveaux composes spiro[2.4]heptane amino carboxy et derives associes

Publications (1)

Publication Number Publication Date
CA2407777A1 true CA2407777A1 (fr) 2001-11-15

Family

ID=25681805

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002407777A Abandoned CA2407777A1 (fr) 2000-05-11 2001-05-11 Nouveaux composes spiro¬2.4|heptane amino carboxy et derives associes

Country Status (1)

Country Link
CA (1) CA2407777A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037240A1 (fr) * 2002-10-22 2004-05-06 Abbott Laboratories Amides et acides de spirocyclopropyle et leurs applications therapeutiques
US7932245B2 (en) 2002-10-22 2011-04-26 Abbott Laboratories Spirocyclopropyl amides and acids and their therapeutic applications

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037240A1 (fr) * 2002-10-22 2004-05-06 Abbott Laboratories Amides et acides de spirocyclopropyle et leurs applications therapeutiques
US7932245B2 (en) 2002-10-22 2011-04-26 Abbott Laboratories Spirocyclopropyl amides and acids and their therapeutic applications

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