CA2405704C - Analogues de bombesine utilises dans le traitement du cancer - Google Patents
Analogues de bombesine utilises dans le traitement du cancer Download PDFInfo
- Publication number
- CA2405704C CA2405704C CA2405704A CA2405704A CA2405704C CA 2405704 C CA2405704 C CA 2405704C CA 2405704 A CA2405704 A CA 2405704A CA 2405704 A CA2405704 A CA 2405704A CA 2405704 C CA2405704 C CA 2405704C
- Authority
- CA
- Canada
- Prior art keywords
- peptide
- trp
- alpha
- aib
- leu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention concerne de nouveaux peptides, en l'occurrence des antagonistes de la bombésine et des peptides du type bombésine, qui sont utiles dans le traitement du cancer. L'invention concerne, en particulier, la conception et la synthèse de ces nouveaux peptides qui comprennent des .alpha.,.alpha.-acides aminés d'une manière spécifique au site. L'invention concerne, en outre, des procédés de génération desdits peptides, des compositions les renfermant et les applications pharmacologiques de ces peptides, notamment dans le traitement et la prévention du cancer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN147/DEL/2000 | 2000-02-24 | ||
IN147DE2000 | 2000-02-24 | ||
PCT/US2000/020873 WO2001062777A1 (fr) | 2000-02-24 | 2000-07-31 | Analogues de bombesine utilises dans le traitement du cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2405704A1 CA2405704A1 (fr) | 2001-08-30 |
CA2405704C true CA2405704C (fr) | 2010-11-16 |
Family
ID=11097032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2405704A Expired - Fee Related CA2405704C (fr) | 2000-02-24 | 2000-07-31 | Analogues de bombesine utilises dans le traitement du cancer |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1261626A1 (fr) |
AU (1) | AU2000265053A1 (fr) |
CA (1) | CA2405704C (fr) |
WO (1) | WO2001062777A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7173006B2 (en) * | 2002-12-23 | 2007-02-06 | Dabur Research Foundation | Drug comprising synthetic peptide analogs for the treatment of cancer |
US8420050B2 (en) | 2003-01-13 | 2013-04-16 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
US7611692B2 (en) | 2003-01-13 | 2009-11-03 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
US7850947B2 (en) | 2003-01-13 | 2010-12-14 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
US7922998B2 (en) | 2003-01-13 | 2011-04-12 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
AU2004314112A1 (en) * | 2003-12-24 | 2005-07-28 | Bracco Imaging S.P.A. | Improved gastrin releasing peptide compounds |
US8193149B2 (en) * | 2007-09-11 | 2012-06-05 | Mondobiotech Laboratories Ag | Use of Peptide YY, alone or in combination with glucagon-like peptide, for use in medicine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU618029B2 (en) * | 1987-11-02 | 1991-12-12 | Imperial Chemical Industries Plc | Polypeptide compounds |
GB8813356D0 (en) * | 1988-06-06 | 1988-07-13 | Ici Plc | Polypeptide compounds |
ZA915740B (en) * | 1990-07-26 | 1992-05-27 | Merrell Dow Pharma | Peptides |
US6492330B1 (en) * | 1996-08-16 | 2002-12-10 | National Institute Of Immunology | Antiangiogenic drugs |
-
2000
- 2000-07-31 AU AU2000265053A patent/AU2000265053A1/en not_active Abandoned
- 2000-07-31 EP EP00952333A patent/EP1261626A1/fr not_active Withdrawn
- 2000-07-31 WO PCT/US2000/020873 patent/WO2001062777A1/fr not_active Application Discontinuation
- 2000-07-31 CA CA2405704A patent/CA2405704C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2000265053A1 (en) | 2001-09-03 |
WO2001062777A1 (fr) | 2001-08-30 |
EP1261626A1 (fr) | 2002-12-04 |
CA2405704A1 (fr) | 2001-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |