CA2403548A1 - Composition et methodes de traitement, de diminution, et de prevention de maladies et troubles cardio-vasculaires avec des polymethoxyflavones - Google Patents

Composition et methodes de traitement, de diminution, et de prevention de maladies et troubles cardio-vasculaires avec des polymethoxyflavones Download PDF

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Publication number
CA2403548A1
CA2403548A1 CA002403548A CA2403548A CA2403548A1 CA 2403548 A1 CA2403548 A1 CA 2403548A1 CA 002403548 A CA002403548 A CA 002403548A CA 2403548 A CA2403548 A CA 2403548A CA 2403548 A1 CA2403548 A1 CA 2403548A1
Authority
CA
Canada
Prior art keywords
quercetin
limocitrin
hydroxy
tetramethoxyflavone
tocotrienol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002403548A
Other languages
English (en)
Inventor
John A. Manthey
Elzbieta Maria Kurowska
Najla Guthrie
Robert M. Horowitz (Deceased)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
KGK SYNERGIE
US Department of Agriculture USDA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/528,488 external-priority patent/US6987125B1/en
Application filed by KGK SYNERGIE, US Department of Agriculture USDA filed Critical KGK SYNERGIE
Publication of CA2403548A1 publication Critical patent/CA2403548A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des compositions et des méthodes de traitement, de diminution et/ou de prévention de maladies et de troubles cardio-vasculaires. Des individus présentant un risque élevé de développer ou d'avoir une maladie ou un trouble cardio-vasculaire peuvent être traités au moyen d'une dose efficace d'un polyméthoxyflavone, notamment des dérivés de limocitrine, des dérivés de quercétine, des polyméthoxyflavones se produisant naturellement, des tocotriénols et des mélanges correspondants de ces composés.
CA002403548A 2000-03-17 2001-03-16 Composition et methodes de traitement, de diminution, et de prevention de maladies et troubles cardio-vasculaires avec des polymethoxyflavones Abandoned CA2403548A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/528,488 2000-03-17
US09/528,488 US6987125B1 (en) 1998-10-06 2000-03-17 Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones
PCT/US2001/008395 WO2001070029A1 (fr) 2000-03-17 2001-03-16 Composition et methodes de traitement, de diminution, et de prevention de maladies et troubles cardio-vasculaires avec des polymethoxyflavones

Publications (1)

Publication Number Publication Date
CA2403548A1 true CA2403548A1 (fr) 2001-09-27

Family

ID=24105873

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002403548A Abandoned CA2403548A1 (fr) 2000-03-17 2001-03-16 Composition et methodes de traitement, de diminution, et de prevention de maladies et troubles cardio-vasculaires avec des polymethoxyflavones

Country Status (4)

Country Link
EP (1) EP1278417A1 (fr)
AU (1) AU2001247471A1 (fr)
CA (1) CA2403548A1 (fr)
WO (1) WO2001070029A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115378A1 (fr) * 2004-05-26 2005-12-08 Kgk Synergize Inc Compositions contenant des flavonoides et des tocotrienols et methodes associees
WO2005115377A1 (fr) * 2004-05-26 2005-12-08 Kgk Synergize Inc Aliments fonctionnels comprenant des flavonoides et des tocotrienols et procedes associes
US7683095B2 (en) 1998-10-06 2010-03-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7201928B1 (en) 1999-09-21 2007-04-10 Rutgers, The State University Of New Jersey Extracts of orange peel for prevention and treatment of cancer
NZ529243A (en) * 2001-05-02 2007-11-30 Kgk Synergize Inc Use of polymethoxylated flavones for treating insulin resistance
JP2008513349A (ja) * 2005-05-24 2008-05-01 ケージーケー シナジャイズ インコーポレイテッド フラボノイドとトコトリエノールを含む機能性食品及びその方法
US7887852B2 (en) 2005-06-03 2011-02-15 Soft Gel Technologies, Inc. Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
AU2007227535A1 (en) * 2006-03-15 2007-09-27 Rutgers, The State University Of New Jersey Hydroxylated polymethoxyflavone compositions
KR101340675B1 (ko) 2011-12-05 2013-12-12 대구한의대학교산학협력단 탄제레틴을 포함하는 심혈관계 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3867541A (en) * 1972-05-03 1975-02-18 Ralph C Robbins Compositions and methods for disaggregating blood cells

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7683095B2 (en) 1998-10-06 2010-03-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones
WO2005115378A1 (fr) * 2004-05-26 2005-12-08 Kgk Synergize Inc Compositions contenant des flavonoides et des tocotrienols et methodes associees
WO2005115377A1 (fr) * 2004-05-26 2005-12-08 Kgk Synergize Inc Aliments fonctionnels comprenant des flavonoides et des tocotrienols et procedes associes
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
US9610276B2 (en) 2013-06-17 2017-04-04 Kgk Synergize, Inc. Compositions and methods for glycemic control of subjects with impaired fasting glucose

Also Published As

Publication number Publication date
EP1278417A1 (fr) 2003-01-29
AU2001247471A1 (en) 2001-10-03
WO2001070029A1 (fr) 2001-09-27

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Legal Events

Date Code Title Description
FZDE Discontinued