CA2402653A1 - Antiseptic coating for the prevention of disease transmission via biofilms - Google Patents

Antiseptic coating for the prevention of disease transmission via biofilms Download PDF

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CA2402653A1
CA2402653A1 CA002402653A CA2402653A CA2402653A1 CA 2402653 A1 CA2402653 A1 CA 2402653A1 CA 002402653 A CA002402653 A CA 002402653A CA 2402653 A CA2402653 A CA 2402653A CA 2402653 A1 CA2402653 A1 CA 2402653A1
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composition according
enzyme
oxidase
coating
composition
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CA2402653C (en
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Jane Dormon
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    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D115/00Coating compositions based on rubber derivatives
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D109/00Coating compositions based on homopolymers or copolymers of conjugated diene hydrocarbons
    • C09D109/06Copolymers with styrene
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D127/00Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Coating compositions based on derivatives of such polymers
    • C09D127/02Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Coating compositions based on derivatives of such polymers not modified by chemical after-treatment
    • C09D127/04Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Coating compositions based on derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
    • C09D127/06Homopolymers or copolymers of vinyl chloride
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D133/00Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/04Homopolymers or copolymers of esters
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D151/00Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
    • C09D151/003Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D153/00Coating compositions based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/14Paints containing biocides, e.g. fungicides, insecticides or pesticides
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/18Fireproof paints including high temperature resistant paints
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00Use of inorganic substances as compounding ingredients
    • C08K3/01Use of inorganic substances as compounding ingredients characterized by their specific function
    • C08K3/016Flame-proofing or flame-retarding additives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/0008Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0058Biocides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/0008Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0066Flame-proofing or flame-retarding additives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00Properties
    • C08L2201/02Flame or fire retardant/resistant
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)

Abstract

The invention provides an improved means for creating a surface that strongly resists microbial colonization. The invention involves a process that can be instigated in the environment of an applied coating. Non-toxic microbicides and halogen-free flame retardants are added as components of the coating which is manufactured using traditional methods and then applied by traditional methods to the hard or soft surface that is to be protected.

Claims (75)

1. A coating composition comprising i. a surface coating material, ii. at least a first enzyme, and iii. at least one flame retarding compound, wherein said first enzyme is capable of directly and/or indirectly inhibiting attachment and/or growth of microorganisms when exposed to moisture after applying said coating composition to a surface and allowing it to form a film.
2. A coating composition comprising i. a surface coating material, ii. at least a first enzyme, and iii. at least one antimicrobial compound, wherein said first enzyme is capable of directly and/or indirectly inhibiting attachment and/or growth of microorganisms when exposed to moisture after applying said coating composition to a surface and allowing it to form a film.
3. A composition according to any of claims 1 to 2, wherein the surface coating material comprises a binder.
4. A composition according to claim 3, wherein the binder comprises a modified rosin such as rosin maleic acid or gloss oil.
5. A composition according to claim 3, wherein the binder comprises a shellac, such as French polish.
6. A composition according to claim 3, wherein the binder comprises an oxidised rubber.
7. A composition according to claim 3, wherein the binder comprises a water-based styrene butadiene latex system.
8. A composition according to claim 3, wherein the binder comprises a water based styrene acrylic.
9. A composition according to claim 3, wherein the binder comprises a chlorinated polyolefin.
10. A composition according to claim 3, wherein the binder comprises a modified water-borne silicone.
11. A composition according to claim 3, wherein the binder comprises at least one compound selected from the group consisting of modified sucrose, water-borne polyvinylidene, chloride based latex terpopolymers, vinyl acetate, polyvinyl alcohol, polivinyl acetals, vinylidene fluoride, polyurethanes, epoxides, water-soluble acrylics.
12. A composition according to any of the preceding claims, wherein the surface coating composition and the binder do not inhibit the activity of the enzyme.
13. A composition according to any of the preceding claims, further comprising a biocide, selected from the group consisting of: zinc oxide; organic biocides such as citrus oil, chilli oil such as herba~ero extract, cranberry extract, seaweed extract (e.g. from Gigartina stellata); non-leaching biocides such as 2,4,4-trichloro-2-hydroxy-diphenyl ether, 5-chloro-2-phenol; polyvalent carbohydrate molecules such as polyvalent glycosylated casein; class V metals such as bismuth; carbamates with diethanolamide as a potentiator.
14. A composition according to any of the preceding claims, further comprising an antibacterial oil selected from the group consisting of vetiver oil, camphor oil, ceder oil, tea-tree oil or citrus oil.
15. A composition according to any of the preceding claims, further comprising a naturally occurring anti-bacterial compound selected from the group consisting of honey, natural tree resins, preferably from pine trees or Elemi; Copal;
Dammar.
16. A composition according to any of the preceding claims, further comprising sodium fluoride and/or dodecylamine and/or tricolsan and/or chlorhexidine.
17. A composition according to any of the preceding claims, further comprising an anti-microbial salt selected from the group consisting of iodide salts and/or metal salts, cupric chloride, cupric sulphate, silver nitrate, colloidal bismuth subcitrate, bismuth citrate, aluminium phosphate, aluminium hydroxide hydrate, gold chloride.
18. A composition according to any of the preceding claims 13 to 17, comprising 0.5 to 30% (w/v) of biocide, such as 1 to 20%, for example 1-5%, or 5-10%, or 10-15%, or 15-20%.
19. A composition according to any of the preceding claims, wherein the flame retardent compound is selected from the group comprising: macroplegmatic compounds; a flame retarding mixture comprising malamine cyanurate, silica, and phosphoric acid; a flame retarding mixture comprising sodium carbonate, pyrophosphate, ammonium salts, boric acid, phosphoric acid; a halogen-based flame retardent such as organic chlorine compounds, organic bromide compounds such as brominated aromatic bisimide compounds, brominated aromatic epoxy compounds, brominated polycarbonates, brominated benzyl arcylates, brominated polystyrene; phosphorous based flame retardents such as phosphate salts, phosphate esters, nitrogen containing phosphorous compounds and red phosphorous; inorganic flame retardents such as zinc borate ammonium borate, ammonium sulphamate, ammonium bromide etc;
oxides of antimony; sodium antimonate; aluminium or magnesium hydroxide.
20. The composition according to claim 19, wherein the flame retardant is non-toxic and/or does not release toxic fumes.
21. The composition according to claim 19, wherein the flame retardant is present in an amount of 1 to 50% (w/v), preferably from 5 to 25%, such as from 5-10%, from 10-15%, from 15-20°l0, or from 20-25%.
22. The composition according to claim 19, comprising up to 75 % (w/v) of an essentially non-combustible binder, such as up to 70%, for example up to 65%, such as up to 60%, for example up to 55%, such as up to 50%, for example up to 45%, such as up to 40%, for example up to 35%, such a up to 30%, for example up to 25%.
23. A composition according to any of the preceding claims, wherein the enzyme and or the substrate for said enzyme are encapsulated such as being encapsulated in mesoporous silicates, porous ceramic particles, porous glass spheres and the like.
24. A composition according to any of the preceding claims, further comprising fibres such as cellulosic fibres.
25. A composition according to claim 24, wherein the enzyme and/or substrate and/or a biocide is/are bound to said fibres.
26. A composition according to any of the preceding claims, further comprising at least one substrate for said enzyme.
27. A composition according to any of the preceding claims, further comprising co-factors for said enzyme.
28. A composition according to any of claims 26 to 27, comprising at least 0.05 (w/v) of substrate for said enzyme, such as at least 0.1 %, for example at least 0.5 %, such as at least 1%, for example at least 2%, such as at least 5%, for example at least 10%, such as at least 15%, for example at least 20%, such as at least 25 %, for example at least 30%, such as at least 40%, for example at least 50%, such as at least 60%.
29. A composition according to any of the preceding claims, wherein hydrogen peroxide is generated in an amount to prevent biofilm formation on the surface of the composition.
30. A composition according to claim 29, being adapted to produce at least 5mM
hydrogen peroxide in an overlying water film, such as at least 6 mM, for example at least 7.5 mM, such as at least 10 mM.
31. A composition according to claim 1, wherein the activity of the at least one enzyme is controllable by changes in ambient humidity and/or ambient temperature and/or ambient pH and/or ambient oxygen levels.
32. A composition according to claim 31, wherein at least one enzyme has an activity sufficient to inhibit biofilm formation, when ambient humidity is above 40%, such as above 45%, for example above 50%, such as above 55%, for example above 60%, such as above 65%, for example above 70%, such as above 75%, for example above 80%, such as above 85%, for example above 90%, such as above 95%.
33. A composition according to claim 31, wherein at least one enzyme has an optimum in the interval between 5-40°C, such as 5-10 °C, 10-15°C, 15-20°C, 20-25°C, 25-30°C, 30-35°C, 35-40°C.
34. A composition according to claim 31, wherein at least one enzyme has an optimum in the interval between pH 4 and 11, such as an optimum in the interval of pH 4-5, pH 5-6, pH 6-7, pH 7-8, pH 8-9, pH 9-10, pH 10-11.
35. A composition according to claim 31, wherein at least one enzyme has an optimum at 50-100 % oxygen saturation.
36. A composition according to any of the preceding claims, wherein the at least one enzyme does not lose substantial activity when dried to and rehydrated repeated times.
37. A composition according to claim 36, wherein the at least one enzyme does not lose substantial activity when dried to below 20% moisture content and rehydrated again, preferably below 19%, such as below 18%, for example below 17%, such as below 16%, for example below 15%, such as below 14%, for example below 13%, such as below 12%, for example below 11 %, such as below 10%, for example below 9%, such as below 8%, for example below 7%, such as below 6 %, for example below 5%, such as below 4%, for example below 3%, such as below 2%, such as below 1.5%, for example below 1 %.
38. A composition according to any of the preceding claims, comprising a combination of first enzyme and substrate selected from the group consisting of combinations as malate oxidase-malic acid; glucose oxidase-glucose; hexose oxidase-glucose; cholesterol oxidase-cholesterol; arylalcohol oxidase-arylalcohol: galactose oxidase-galactose; alcohol oxidase-alcohol; lathosterol oxidase-lathosterol; aspartate oxidase-aspartic acid; L-amino-acid oxidase-L-amino acid; D-amino-acid oxidase-D-amino acid; amine oxidase-amine; D-glutamate oxidase-glutamine; ethanolamine oxidase-ethanolamine; NADH
oxidase-NADH; urate oxidase (uricase)-uric acid; superoxide dismutase-superoxide radical; glucose/hexose oxidase; glucose/glucose oxidase; L amino acid/L amino acid oxidase; galactose/galactose oxidase; lactose/P-galactosidase/hexose oxidase; lactose/ -galactosidase/glucose oxidase; 2-deoxyglucose/glucose oxidase; pyranose/pyranose oxidase; and mixtures thereof.
39. A composition according to any of the preceding claims, comprising at least 0.0001 % (w/v) of enzyme, such as at least 0.001 %, for example at least 0.01 such as at least 0.05, for example at least 0.1 %, such as at least 0.5%, such as at least 1 %, for example at least: 1.5%, such as at least 2%, for example at least 2.5%, such as at least 3%, for example at least 3.5%, such as at least 4%, for example at least 4.5%, such as at least 5%.
40. A composition according to any of the preceding claims, further comprising a second enzyme capable of converting a compound into a substrate for the first enzyme.
41. A composition according to claim 40, wherein said second enzyme is an amylase, a fructase, a cellulase, a ligninase, a proteinase, or a nuclease.
42. A composition according to claim 41, wherein said compound is a fructan such as inulin.
43. A composition according to any of the preceding claims, comprising at least 2 enzymes, such as at least 3 enzymes, for example at least 4 enzymes, such as at least 5 enzymes, for example at least 6 enzymes, such as at least 10 enzymes.
44. A composition according to claim 43, comprising a protease, a lipase, an amylase and/or an oxidase.
45. A composition according to any of the preceding claims, further comprising a stain/coulour such as iron oxide, titanium oxide, and/or zinc oxide.
46. A composition according to any of the preceding claims, comprising enzyme and optionally substrate enough to ensure biofilm prevention for a period of at least 6 months, preferably at least 1 year, more preferably at least 1 1/2 years, more preferably at least 2 years, more preferably at least 3 years, such as at least 4, 5 or 6 years.
47. Use of a composition according to any of the preceding claims.
48. The use according to claim 47 for coating surfaces in enclosed habits such as a spacecraft.
49. The use according to claim 47 for coating surfaces in a ventilation system.
50. The use according to claim 47 for coating surfaces in an aeroplane.
51. The use according to claim 47 for coating surfaces in medical and other health care systems such as operating theatres.
52. The use according to claim 47 for coating surfaces in educational facilities.
53. The use according to claim 47 for coating surfaces in vehicles, such as a bus, ambulance, mobile home, caravan, a ship/yacht interior.
54. The use according to claim 47 for coating surfaces in sports facilities.
55. The use according to claim 47 for coating surfaces in public buildings and offices.
56. The use according to claim 47 for coating surfaces in private homes, preferably in bathrooms and/or kitchens.
57. The use according to claim 47 for coating surfaces in animal housings such as stables.
58. The use according to claim 47 for coating surfaces in pulp mills.
59. The use according to claim 47 for coating surfaces in food preparation facilities
60. The use according to claim 47 for coating surfaces slaughterhouses and/or abattoirs
61. The use according to claim 47 for coating surfaces in sanitation facilities, including sewage farms and public toilets.
62. A method for controlling growth of microorganisms on coated surfaces comprising applying to a surface a coating composition comprising a surface coating material, at least one enzyme, and a substrate for said enzyme, allowing said coating composition to form a film, whereby said coating composition upon subsequent exposure to moisture levels above 50% releases an antimicrobially effective amount of an antimicrobially active compound as a consequence of a conversion of said substrate through said enzyme.
63. A method for controlling growth of microorganisms on coated surfaces comprising applying to a surface a coating composition comprising a surface coating material, at least one enzyme, allowing said coating composition to form a film, whereby said coating composition upon subsequent exposure to moisture levels above 50% (RN) inhibits attachment of at least one species of microorganism as a consequence of a the action of said enzyme.
64. The method according to claim 62 or 63, wherein said coating composition is a coating composition according to any of claims 1 to 46.
65. The method according to claim 62 or 63, wherein said surface is a surface in a spacecraft.
66. The method according to claim 62 or 63, wherein said surface is a surface in a ventilation system.
67. The method according to claim 62 or 63, wherein said surface is a surface in a ship, such as a yacht, or a submarine.
68. The method according to claim 62 or 63, wherein said surface is a surface in a vehicle, such as an aeroplane, bus, ambulance, mobile home, caravan.
69. The method according to claim 62 or 63, wherein said surface is a surface in a medical or health care building or room.
70. The method according to claim 62 or 63, wherein said surface is a surface in a public building.
71. The method according to claim 62 or 63, wherein said surface is a surface in a private house, such as in a kitchen or bath room.
72 The method according to claim 62 or 63, wherein said surface is a surface in a animal housing, such as a stable.
73. The method according to claim 62 or 63, wherein said surface is a surface in a food preparation facility, such as a kitchen, a slaughterhouse, an abattoir.
74. The method according to claim 62 or 63, wherein said surface is a surface in a sanitation facility, such as a public toilet, a sewage farm.
75. The method according to claim 62 or 63, wherein said surface is a surface in an industrial facility such as a pulp mill.
CA2402653A 2002-09-26 2002-09-26 Antiseptic coating for the prevention of disease transmission via biofilms Expired - Lifetime CA2402653C (en)

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Cited By (18)

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WO2008086402A1 (en) * 2007-01-09 2008-07-17 Inframat Corporation Coating compositions for marine applications and methods of making and using the same
WO2008156711A1 (en) * 2007-06-12 2008-12-24 E. I. Du Pont De Nemours And Company Electrodeposition baths containing a mixture of boron-containing compounds and chlorhexidine
WO2008156710A1 (en) * 2007-06-12 2008-12-24 E. I. Du Pont De Nemours And Company Electrodeposition baths containing a mixture of boron-containing compounds and chlorhexidine
WO2009117633A2 (en) 2008-03-21 2009-09-24 General Cable Technologies Corporation Low-smoke, fire-resistant and water-resistant cable coating
AU2004241665B2 (en) * 2003-05-21 2009-10-08 Novapharm Research (Australia) Pty Ltd Biofilm growth prevention
CN101382515B (en) * 2008-10-29 2011-11-02 北京化工大学 Ethanol oxidizing enzyme film using polycarbonate film as substrate and method for making same
EP2479225A2 (en) * 2009-09-18 2012-07-25 LG Chem, Ltd. Novel use of a lipolytic enzyme for forming an anti-fingerprint coating, method for forming anti-fingerprint coating, substrate comprising the anti-fingerprint coating formed by the method, and products comprising the substrate
CN101602899B (en) * 2008-06-12 2012-10-24 三棵树涂料股份有限公司 Biological-enzyme inner-wall environment-friendly coating
US8524799B2 (en) * 2003-05-21 2013-09-03 Novapharm Research (Australia) Pty Ltd Biofilm growth prevention
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WO2013179323A1 (en) * 2012-06-01 2013-12-05 Stm Technologies S.R.L. Formaldehyde free binding composition, for mineral fibres
CN104962148A (en) * 2015-07-07 2015-10-07 饶烨 Antibacterial flame-retardant paint and preparation method thereof
CN105255269A (en) * 2015-10-30 2016-01-20 无锡市长安曙光手套厂 Mildew-proof composite material and preparation method of mildew-proof composite material
CN107118674A (en) * 2017-05-31 2017-09-01 安庆永大体育用品有限公司 A kind of slide plate good alkyd paint of anti-microbial property and preparation method thereof
CN109161280A (en) * 2018-06-28 2019-01-08 芜湖市三山龙城新材料有限公司 A kind of energy-saving heat preserving building coating of heat resistant and preparation method thereof
CN109593363A (en) * 2018-11-23 2019-04-09 唐山师范学院 Retarding chamber temperature vulcanizable silicone rubber compounding and fire-retardant room temperature vulcanized silicone rubber
CN111349234A (en) * 2020-04-30 2020-06-30 深圳市前海博扬研究院有限公司 Flame-retardant polyurea and synthesis method thereof
WO2021240182A1 (en) * 2020-05-25 2021-12-02 Nanophos Sa Silicone-epoxy compositions and protective coatings

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