CA2400254A1 - Compositions et methodes pour traiter une maladie du coeur - Google Patents
Compositions et methodes pour traiter une maladie du coeur Download PDFInfo
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- CA2400254A1 CA2400254A1 CA002400254A CA2400254A CA2400254A1 CA 2400254 A1 CA2400254 A1 CA 2400254A1 CA 002400254 A CA002400254 A CA 002400254A CA 2400254 A CA2400254 A CA 2400254A CA 2400254 A1 CA2400254 A1 CA 2400254A1
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- pi3kgamma
- pten
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- heart
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- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0375—Animal model for cardiovascular diseases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Environmental Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002400254A CA2400254A1 (fr) | 2002-09-19 | 2002-09-19 | Compositions et methodes pour traiter une maladie du coeur |
CA002499368A CA2499368A1 (fr) | 2002-09-19 | 2003-09-19 | Compositions et methodes de traitement d'une maladie cardiaque |
AU2003269626A AU2003269626A1 (en) | 2002-09-19 | 2003-09-19 | Compositions and methods for treating heart disease |
EP03750190A EP1539177A2 (fr) | 2002-09-19 | 2003-09-19 | Compositions et methodes de traitement d'une maladie cardiaque |
PCT/CA2003/001387 WO2004026285A2 (fr) | 2002-09-19 | 2003-09-19 | Compositions et methodes de traitement d'une maladie cardiaque |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002400254A CA2400254A1 (fr) | 2002-09-19 | 2002-09-19 | Compositions et methodes pour traiter une maladie du coeur |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2400254A1 true CA2400254A1 (fr) | 2004-03-19 |
Family
ID=32000082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002400254A Abandoned CA2400254A1 (fr) | 2002-09-19 | 2002-09-19 | Compositions et methodes pour traiter une maladie du coeur |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1539177A2 (fr) |
AU (1) | AU2003269626A1 (fr) |
CA (1) | CA2400254A1 (fr) |
WO (1) | WO2004026285A2 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667300B2 (en) | 2000-04-25 | 2003-12-23 | Icos Corporation | Inhibitors of human phosphatidylinositol 3-kinase delta |
EP3943494A1 (fr) | 2004-05-13 | 2022-01-26 | Icos Corporation | Quinazolinones utilisées en tant qu'inhibiteurs de la phosphatidylinositol 3-kinase delta humaine |
US9492449B2 (en) | 2008-11-13 | 2016-11-15 | Gilead Calistoga Llc | Therapies for hematologic malignancies |
NZ631024A (en) | 2008-11-13 | 2016-04-29 | Gilead Calistoga Llc | Therapies for hematologic malignancies |
MX2011009955A (es) | 2009-03-24 | 2011-11-18 | Gilead Calistoga Llc | Atropisomeros de derivados de 2-purinil-3-tolil-quinazolinona y metodos de uso. |
ES2548253T3 (es) | 2009-04-20 | 2015-10-15 | Gilead Calistoga Llc | Métodos para el tratamiento de tumores sólidos |
EP2456443A1 (fr) | 2009-07-21 | 2012-05-30 | Gilead Calistoga LLC | Traitement de troubles du foie par des inhibiteurs de pi3k |
JP2015509537A (ja) | 2012-03-05 | 2015-03-30 | ギリアード カリストガ エルエルシー | (s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの多形性形態 |
CA2934534A1 (fr) | 2013-12-20 | 2015-06-25 | Gilead Calistoga Llc | Formes polymorphes d'un sel chlorhydrate de la (s)-2-(1-(9h-purine-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one |
NZ720867A (en) | 2013-12-20 | 2018-01-26 | Gilead Calistoga Llc | Process methods for phosphatidylinositol 3-kinase inhibitors |
MX2016016530A (es) | 2014-06-13 | 2017-03-27 | Gilead Sciences Inc | Inhibidores de fosfatidilinositol 3-quinasa. |
BR112017013453B1 (pt) * | 2014-12-24 | 2024-02-27 | Kither Biotech S.R.L. | Produto, composição farmacêutica e uso do peptídeo de fusão |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4990599A (en) * | 1998-07-14 | 2000-02-07 | Brigham And Women's Hospital | Upregulation of type iii endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization |
-
2002
- 2002-09-19 CA CA002400254A patent/CA2400254A1/fr not_active Abandoned
-
2003
- 2003-09-19 AU AU2003269626A patent/AU2003269626A1/en not_active Abandoned
- 2003-09-19 EP EP03750190A patent/EP1539177A2/fr not_active Withdrawn
- 2003-09-19 WO PCT/CA2003/001387 patent/WO2004026285A2/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2003269626A1 (en) | 2004-04-08 |
WO2004026285A2 (fr) | 2004-04-01 |
WO2004026285A3 (fr) | 2004-07-29 |
EP1539177A2 (fr) | 2005-06-15 |
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