CA2396883A1 - Diagnostic non invasif de maladies de la peau par spectroscopie dans le visible/l'infrarouge proche - Google Patents
Diagnostic non invasif de maladies de la peau par spectroscopie dans le visible/l'infrarouge proche Download PDFInfo
- Publication number
- CA2396883A1 CA2396883A1 CA002396883A CA2396883A CA2396883A1 CA 2396883 A1 CA2396883 A1 CA 2396883A1 CA 002396883 A CA002396883 A CA 002396883A CA 2396883 A CA2396883 A CA 2396883A CA 2396883 A1 CA2396883 A1 CA 2396883A1
- Authority
- CA
- Canada
- Prior art keywords
- disease
- skin
- spectrum
- skin disease
- control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/444—Evaluating skin marks, e.g. mole, nevi, tumour, scar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
L'invention concerne un outil non invasif pour effectuer le diagnostic de maladies de la peau, destiné à être utilisé en tant que dispositif clinique auxiliaire. L'étude sur laquelle est fondée cette invention avait pour but de déterminer si la spectroscopie dans le visible/infrarouge proche peut être exploité pour la caractérisation non invasive de maladies de la peau. Des spectres in vivo dans le visible et infrarouge proche (400-2500 nm) de tumeurs de la peau (kératoses séniles, carcinomes basocellulaires, naevus mélanocytaires banals communs acquis, naevus mélanocytaires dysplastiques, lentigines actiniques et kératoses séborrhéiques) ont été obtenus au moyen d'une sonde à fibre optique placée sur la peau. On a fait appel à des tests t jumelés, à une analyse de variance et à une analyse discriminatoire de mesures répétées pour déterminer s'il y avait des différences spectrales significatives et si les spectres pouvaient être classés selon le type de lésion. Les tests t jumelés ont montré des différences significatives (p<0,05) entre une peau normale et une peau présentant des lésions, dans plusieurs zones du spectre visible/infrarouge proche. En outre, des différences significatives ont été trouvées entre les groupes de lésions, par analyse de variance. L'analyse discriminatoire linéaire a permis de différencier des spectres résultant de lésions bénignes, en comparaison avec des lésions pré-malignes ou malignes. La spectroscopie dans le visible/infrarouge rouge constitue une technique non invasive prometteuse pour le diagnostic de maladies de la peau.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15785799P | 1999-10-06 | 1999-10-06 | |
US60/157,857 | 1999-10-06 | ||
PCT/CA2000/001187 WO2001024699A2 (fr) | 1999-10-06 | 2000-10-05 | Diagnostic non invasif de maladies de la peau par spectroscopie dans le visible/l'infrarouge proche |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2396883A1 true CA2396883A1 (fr) | 2001-04-12 |
CA2396883C CA2396883C (fr) | 2011-04-12 |
Family
ID=22565569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2396883A Expired - Lifetime CA2396883C (fr) | 1999-10-06 | 2000-10-05 | Diagnostic non invasif de maladies de la peau par spectroscopie dans le visible/l'infrarouge proche |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1237479A2 (fr) |
AU (1) | AU782431B2 (fr) |
CA (1) | CA2396883C (fr) |
WO (1) | WO2001024699A2 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10346757A1 (de) * | 2003-10-06 | 2005-05-12 | Pe Diagnostik Gmbh | Verfahren zur Klassifikation von Messwerten in der medizinischen und biochemischen Analytik |
WO2010085954A1 (fr) * | 2009-01-29 | 2010-08-05 | Leo Pharma A/S | Procédé de détermination de l'état d'un trouble cutané au moyen de la spectroscopie infrarouge proche |
WO2011048596A1 (fr) | 2009-10-23 | 2011-04-28 | Boris Melnik | Système et procédé d'examen de tissu non invasif |
US11045494B2 (en) | 2015-07-10 | 2021-06-29 | Infectopharm Arzneimittel Und Consilium Gmbh | Use of potassium hydroxide in the treatment of actinic keratosis |
MX2021004642A (es) * | 2018-10-23 | 2021-07-02 | Aesthetics Biomedical Inc | Metodos, dispositivos y sistemas para inducir la regeneracion del colageno. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5016173A (en) * | 1989-04-13 | 1991-05-14 | Vanguard Imaging Ltd. | Apparatus and method for monitoring visually accessible surfaces of the body |
US6008889A (en) * | 1997-04-16 | 1999-12-28 | Zeng; Haishan | Spectrometer system for diagnosis of skin disease |
-
2000
- 2000-10-05 CA CA2396883A patent/CA2396883C/fr not_active Expired - Lifetime
- 2000-10-05 WO PCT/CA2000/001187 patent/WO2001024699A2/fr not_active Application Discontinuation
- 2000-10-05 AU AU77662/00A patent/AU782431B2/en not_active Ceased
- 2000-10-05 EP EP00967472A patent/EP1237479A2/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2001024699A8 (fr) | 2001-10-04 |
EP1237479A2 (fr) | 2002-09-11 |
CA2396883C (fr) | 2011-04-12 |
AU782431B2 (en) | 2005-07-28 |
AU7766200A (en) | 2001-05-10 |
WO2001024699A2 (fr) | 2001-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |