CA2396401A1 - Nouvel homologue du fgf, zfgf12 - Google Patents
Nouvel homologue du fgf, zfgf12 Download PDFInfo
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- CA2396401A1 CA2396401A1 CA002396401A CA2396401A CA2396401A1 CA 2396401 A1 CA2396401 A1 CA 2396401A1 CA 002396401 A CA002396401 A CA 002396401A CA 2396401 A CA2396401 A CA 2396401A CA 2396401 A1 CA2396401 A1 CA 2396401A1
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
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- Genetics & Genomics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
Abstract
La présente invention concerne des molécules polynucléotidiques et polypeptidiques du zFGF12, un nouveau membre de la famille des FGF. La présente invention concerne également des anticorps des polypeptides du zFGF12, et des méthodes d'utilisation des polynucléotides et des polypeptides.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47806200A | 2000-01-05 | 2000-01-05 | |
| US09/478,062 | 2000-01-05 | ||
| PCT/US2001/000238 WO2001049740A1 (fr) | 2000-01-05 | 2001-01-04 | Nouvel homologue du fgf, zfgf12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2396401A1 true CA2396401A1 (fr) | 2001-07-12 |
Family
ID=23898370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002396401A Abandoned CA2396401A1 (fr) | 2000-01-05 | 2001-01-04 | Nouvel homologue du fgf, zfgf12 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1246843A1 (fr) |
| JP (1) | JP2003518944A (fr) |
| AU (1) | AU2759201A (fr) |
| CA (1) | CA2396401A1 (fr) |
| WO (1) | WO2001049740A1 (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02007619A (es) * | 2000-02-15 | 2002-12-13 | Amgen Inc | Moleculas de factor 23 de crecimiento de fibroblastos y su uso. |
| EP1947182A1 (fr) * | 2000-02-15 | 2008-07-23 | Amgen Inc. | Molécules 23 à facteur de croissance de fibroblaste et utilisations associées |
| WO2001066595A2 (fr) * | 2000-03-08 | 2001-09-13 | Chiron Corporation | Gene humain fgf-23 et produits d'expression associes |
| WO2001066596A2 (fr) * | 2000-03-08 | 2001-09-13 | Chiron Corporation | Gene humain fgf-23 et produits d'expression genique |
| CA2418215A1 (fr) | 2000-07-19 | 2002-01-31 | Advanced Research & Technology Institute | Nouveau facteur de croissance fibroblastique (fgf23) et ses methodes d'utilisation |
| DE60142239D1 (de) | 2000-08-11 | 2010-07-08 | Kyowa Hakko Kirin Co Ltd | DEN PHOSPHORSÄURE-METABOLISMUS, DEN KALZIUM-METABOLISMUS, VERKALKUNG UND DEN VITAMIN D-METABOLISMUS KONTROLLIERENDE POLYPEPTIDE SOWIE FüR DIESE KODIERENDE DNA-MOLEKÜLE |
| ATE441666T1 (de) * | 2001-12-28 | 2009-09-15 | Kyowa Hakko Kirin Co Ltd | Antikírper gegen den fibroblastenwachstumsfaktor 23 |
| EP1728514A1 (fr) * | 2005-06-03 | 2006-12-06 | Immunotech S.A. | Utilisations d'oligonucléotides stimulateurs de cellules souches mésenchymateuses |
| US7883705B2 (en) | 2007-02-14 | 2011-02-08 | Kyowa Hakko Kirin Co., Ltd. | Anti FGF23 antibody and a pharmaceutical composition comprising the same |
| KR102077721B1 (ko) | 2011-07-01 | 2020-02-14 | 엔지엠 바이오파마슈티컬스, 아이엔씨. | 대사성 장애 및 질환의 치료를 위한 조성물, 용도 및 방법 |
| EP3798228A1 (fr) | 2012-11-28 | 2021-03-31 | NGM Biopharmaceuticals, Inc. | Compositions et procédés pour le traitement de troubles métaboliques et de maladies |
| US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
| ES2915851T3 (es) | 2012-12-27 | 2022-06-27 | Ngm Biopharmaceuticals Inc | Péptidos quiméricos de FGF19 para usar en el tratamiento de trastornos de ácidos biliares |
| US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| CA2927592C (fr) | 2013-10-28 | 2020-08-18 | Ngm Biopharmaceuticals, Inc. | Variants de fgf-19 pour le traitement d'un cancer ou d'une tumeur fgf-19-dependant |
| EP3097122B9 (fr) | 2014-01-24 | 2020-11-11 | NGM Biopharmaceuticals, Inc. | Anticorps liant beta-klotho 2 et leurs procédés d'utilisation |
| WO2015183890A2 (fr) | 2014-05-28 | 2015-12-03 | Ngm Biopharmaceuticals, Inc. | Méthodes et compositions pour le traitement de maladies et de troubles métaboliques |
| US10456449B2 (en) | 2014-06-16 | 2019-10-29 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| IL251834B2 (en) | 2014-10-23 | 2023-09-01 | Ngm Biopharmaceuticals Inc | Pharmaceutical compositions containing peptide variants and methods of using them |
| WO2016073855A1 (fr) | 2014-11-07 | 2016-05-12 | Ngm Biopharmaceuticals, Inc. | Procédés de traitement de troubles liés à l'acide biliaire et prédiction de la sensibilité clinique au traitement de troubles liés aux acides biliaires |
| US10800843B2 (en) | 2015-07-29 | 2020-10-13 | Ngm Biopharmaceuticals, Inc. | Beta klotho-binding proteins |
| CA3082794A1 (fr) | 2015-11-09 | 2017-05-18 | Ngm Biopharmaceuticals Inc. | Methodes de traitement de troubles associes aux acides biliaires |
| EP3503882A4 (fr) | 2016-08-26 | 2020-07-29 | NGM Biopharmaceuticals, Inc. | Méthodes de traitement de cancers et de tumeurs à médiation assurée par le facteur de croissance des fibroblastes 19 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859208A (en) * | 1988-07-06 | 1999-01-12 | Fiddes; John C. | Human basic fibroblast growth factor analog |
| JP2879148B2 (ja) * | 1987-07-07 | 1999-04-05 | サイオス インコーポレイテッド | 組換え繊維芽細胞成長因子 |
| AU712297B2 (en) * | 1995-06-05 | 1999-11-04 | Human Genome Sciences, Inc. | Fibroblast growth factor 11 |
| KR100506786B1 (ko) * | 1997-11-25 | 2005-08-08 | 제넨테크, 인크. | 섬유아세포 성장인자-19 |
-
2001
- 2001-01-04 EP EP01901722A patent/EP1246843A1/fr not_active Withdrawn
- 2001-01-04 JP JP2001550280A patent/JP2003518944A/ja active Pending
- 2001-01-04 CA CA002396401A patent/CA2396401A1/fr not_active Abandoned
- 2001-01-04 AU AU27592/01A patent/AU2759201A/en not_active Abandoned
- 2001-01-04 WO PCT/US2001/000238 patent/WO2001049740A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003518944A (ja) | 2003-06-17 |
| AU2759201A (en) | 2001-07-16 |
| EP1246843A1 (fr) | 2002-10-09 |
| WO2001049740A1 (fr) | 2001-07-12 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Dead |