CA2390017A1 - Presentation de surface cellulaire de proteines par des cellules hotes recombinantes - Google Patents

Presentation de surface cellulaire de proteines par des cellules hotes recombinantes Download PDF

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Publication number
CA2390017A1
CA2390017A1 CA002390017A CA2390017A CA2390017A1 CA 2390017 A1 CA2390017 A1 CA 2390017A1 CA 002390017 A CA002390017 A CA 002390017A CA 2390017 A CA2390017 A CA 2390017A CA 2390017 A1 CA2390017 A1 CA 2390017A1
Authority
CA
Canada
Prior art keywords
gene
nucleic acid
acid molecule
nucleotide sequence
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002390017A
Other languages
English (en)
Inventor
Si Lok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Si Lok
Zymogenetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Si Lok, Zymogenetics, Inc. filed Critical Si Lok
Publication of CA2390017A1 publication Critical patent/CA2390017A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
CA002390017A 1999-11-04 2000-11-01 Presentation de surface cellulaire de proteines par des cellules hotes recombinantes Abandoned CA2390017A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43348999A 1999-11-04 1999-11-04
US09/433,489 1999-11-04
PCT/US2000/030238 WO2001032894A1 (fr) 1999-11-04 2000-11-01 Presentation de surface cellulaire de proteines par des cellules hotes recombinantes

Publications (1)

Publication Number Publication Date
CA2390017A1 true CA2390017A1 (fr) 2001-05-10

Family

ID=23720313

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002390017A Abandoned CA2390017A1 (fr) 1999-11-04 2000-11-01 Presentation de surface cellulaire de proteines par des cellules hotes recombinantes

Country Status (4)

Country Link
EP (1) EP1226258A1 (fr)
AU (1) AU1455501A (fr)
CA (1) CA2390017A1 (fr)
WO (1) WO2001032894A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1943332A4 (fr) 2005-10-14 2011-04-13 Medimmune Inc Affichage cellulaire de libraires d'anticorps
GB0523826D0 (en) * 2005-11-23 2006-01-04 Ares Trading Sa Signal anchored protein
US20230096053A1 (en) * 2019-12-06 2023-03-30 The Board Of Trustees Of The Leland Stanford Junior University Genetically-targeted chemical assembly: building functional structures and materials in living cells, tissues, and animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989007140A1 (fr) * 1988-02-05 1989-08-10 Commonwealth Scientific And Industrial Research Or Systeme d'expression par genes (en particulier pour la proteine de rotavirus vp7) employant un peptide de signal etranger et eventuellement une sequence d'ancrage transmembrane
US5821088A (en) * 1990-05-11 1998-10-13 Siga Pharmaceuticals, Inc. Use of gram-positive bacteria to express recombinant proteins
JPH10243784A (ja) * 1997-03-03 1998-09-14 Sagami Chem Res Center Ｉｉ型膜蛋白質をコードする遺伝子の同定方法

Also Published As

Publication number Publication date
AU1455501A (en) 2001-05-14
WO2001032894A1 (fr) 2001-05-10
EP1226258A1 (fr) 2002-07-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued