CA2389911A1 - Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes - Google Patents

Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes Download PDF

Info

Publication number
CA2389911A1
CA2389911A1 CA002389911A CA2389911A CA2389911A1 CA 2389911 A1 CA2389911 A1 CA 2389911A1 CA 002389911 A CA002389911 A CA 002389911A CA 2389911 A CA2389911 A CA 2389911A CA 2389911 A1 CA2389911 A1 CA 2389911A1
Authority
CA
Canada
Prior art keywords
peptide
amino acid
seq
acid sequence
pyrogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002389911A
Other languages
English (en)
Inventor
Raymond Kaempfer
Arad Gila
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2001377682A priority Critical patent/JP4076766B2/ja
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Priority to CA002389911A priority patent/CA2389911A1/fr
Publication of CA2389911A1 publication Critical patent/CA2389911A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA002389911A 2001-12-11 2002-06-10 Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes Abandoned CA2389911A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2001377682A JP4076766B2 (ja) 2001-12-11 2001-12-11 発熱性外毒素に対する広スペクトルアンタゴニストおよびワクチン
CA002389911A CA2389911A1 (fr) 2001-12-11 2002-06-10 Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001377682A JP4076766B2 (ja) 2001-12-11 2001-12-11 発熱性外毒素に対する広スペクトルアンタゴニストおよびワクチン
CA002389911A CA2389911A1 (fr) 2001-12-11 2002-06-10 Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes

Publications (1)

Publication Number Publication Date
CA2389911A1 true CA2389911A1 (fr) 2003-12-10

Family

ID=32991630

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002389911A Abandoned CA2389911A1 (fr) 2001-12-11 2002-06-10 Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes

Country Status (2)

Country Link
JP (1) JP4076766B2 (fr)
CA (1) CA2389911A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8535672B2 (en) 2002-04-04 2013-09-17 Yissum Research Development Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between CD28 and the superantigen and uses thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8535672B2 (en) 2002-04-04 2013-09-17 Yissum Research Development Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between CD28 and the superantigen and uses thereof
US9546207B2 (en) 2002-04-04 2017-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between CD28 and the superantigen and uses thereof

Also Published As

Publication number Publication date
JP2003192696A (ja) 2003-07-09
JP4076766B2 (ja) 2008-04-16

Similar Documents

Publication Publication Date Title
Kane et al. Virulence factor targeting of the bacterial pathogen Staphylococcus aureus for vaccine and therapeutics
Little et al. Molecular pathogenesis of Bacillus anthracis infection
Bhatnagar et al. Anthrax toxin
Baillie et al. An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor
Podda et al. Metabolic, humoral, and cellular responses in adult volunteers immunized with the genetically inactivated pertussis toxin mutant PT-9K/129G.
US10174085B2 (en) Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof
US7189398B2 (en) Broad spectrum pyrogenic exotoxins antagonists and vaccines
CZ20023662A3 (cs) Sloučeniny a způsoby léčení a prevence bakteriální infekce
US20160074497A1 (en) Staphylococcus live cell vaccines
US20060222650A1 (en) Broad spectrum pyrogenic antagonists and vaccines directed against pyrogenic exotoxins
US6835818B2 (en) Mutants of Streptococcal toxin C and methods of use
Little Anthrax vaccines: a development update
CA2760239A1 (fr) Polypeptide derive d'enterocoque et son utilisation pour une vaccination
WO2010089340A2 (fr) Peptides protecteurs contre e. faecalis, procédés et utilisations liés à ceux-ci
Kaur et al. Recent progress in the development of anthrax vaccines
WO2005007804A2 (fr) Vaccin conjugue contre l'anthrax et anticorps diriges contre des bacilles et des toxines de l'anthrax
CA2389911A1 (fr) Antagonistes et vaccins a large spectre contre des exotoxines pyrogenes
Dhasmana et al. Recent developments in anti-dotes against anthrax
AU2022204585A1 (en) Vaccine constructs and uses thereof against staphylococcus infections
Millard et al. 17Ricin and Related Toxins: Review and Perspective
Koirala Development of Peptide-Based Probes to Target Quorum Sensing in Streptococcus pneumoniae
Grund Burkholderia Collagen-Like Protein 8, Bucl8, Is an Outer-Membrane Component of a Novel Efflux Pump and Immunogenic Vaccine Candidate
EP3415160B1 (fr) Polypeptides dérivés de l'enterococcus et leur utilisation pour la vaccination et la génération d'anticorps thérapeutiques
US20050010034A1 (en) Mutants of streptococcal toxin C and methods of use
Vercelli Molecular mechanisms in allergy and clinical immunology

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead