CA2388530A1 - Melange therapeutique d'inhibiteurs de hmg-coa reductase - Google Patents

Melange therapeutique d'inhibiteurs de hmg-coa reductase Download PDF

Info

Publication number
CA2388530A1
CA2388530A1 CA002388530A CA2388530A CA2388530A1 CA 2388530 A1 CA2388530 A1 CA 2388530A1 CA 002388530 A CA002388530 A CA 002388530A CA 2388530 A CA2388530 A CA 2388530A CA 2388530 A1 CA2388530 A1 CA 2388530A1
Authority
CA
Canada
Prior art keywords
hmg
coa reductase
arginine
reductase inhibitor
pravastatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002388530A
Other languages
English (en)
Inventor
Wayne H. Kaesemeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitrosystems Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2388530A1 publication Critical patent/CA2388530A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des mélanges thérapeutiques de statines, seules ou combinées à la L-arginine.
CA002388530A 1999-10-19 2000-10-19 Melange therapeutique d'inhibiteurs de hmg-coa reductase Abandoned CA2388530A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42081699A 1999-10-19 1999-10-19
US09/420,816 1999-10-19
PCT/US2000/041304 WO2001028499A2 (fr) 1999-10-19 2000-10-19 Melange therapeutique d'inhibiteurs de hmg-coa reductase

Publications (1)

Publication Number Publication Date
CA2388530A1 true CA2388530A1 (fr) 2001-04-26

Family

ID=23667961

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002388530A Abandoned CA2388530A1 (fr) 1999-10-19 2000-10-19 Melange therapeutique d'inhibiteurs de hmg-coa reductase

Country Status (5)

Country Link
EP (1) EP1225885A4 (fr)
AU (1) AU2116201A (fr)
CA (1) CA2388530A1 (fr)
MX (1) MXPA02004021A (fr)
WO (1) WO2001028499A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6425881B1 (en) * 1994-10-05 2002-07-30 Nitrosystems, Inc. Therapeutic mixture useful in inhibiting lesion formation after vascular injury
JP2002539257A (ja) 1999-03-19 2002-11-19 イーノス・ファーマシューティカルス・インコーポレーテッド 薬剤の脳内生物学的利用率の増加
USRE44578E1 (en) 2000-04-10 2013-11-05 Teva Pharmaceutical Industries, Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
WO2006099244A1 (fr) * 2005-03-11 2006-09-21 Hong Kong Nitric Oxide Limited Combinaison de traitement pour les troubles endotheliaux, l’angine et le diabete
CN105246472B (zh) * 2013-03-15 2018-10-12 武汉朗来科技发展有限公司 含有鸟氨酸和/或门冬氨酸的组合物及其应用
WO2014139469A1 (fr) * 2013-03-15 2014-09-18 Wuhan Qr Science And Technology Development Co. Compositions comprenant de l'ornithine ou de l'aspartate et utilisations associées

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447922A (en) * 1994-08-24 1995-09-05 Bristol-Myers Squibb Company α-phosphonosulfinic squalene synthetase inhibitors
US5968983A (en) * 1994-10-05 1999-10-19 Nitrosystems, Inc Method and formulation for treating vascular disease

Also Published As

Publication number Publication date
WO2001028499A3 (fr) 2001-10-04
WO2001028499A2 (fr) 2001-04-26
AU2116201A (en) 2001-04-30
EP1225885A2 (fr) 2002-07-31
MXPA02004021A (es) 2004-08-23
EP1225885A4 (fr) 2004-04-21

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead