CA2386199A1 - Polypeptides de type endozepine et polynucleotides codant ces derniers - Google Patents

Polypeptides de type endozepine et polynucleotides codant ces derniers Download PDF

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Publication number
CA2386199A1
CA2386199A1 CA002386199A CA2386199A CA2386199A1 CA 2386199 A1 CA2386199 A1 CA 2386199A1 CA 002386199 A CA002386199 A CA 002386199A CA 2386199 A CA2386199 A CA 2386199A CA 2386199 A1 CA2386199 A1 CA 2386199A1
Authority
CA
Canada
Prior art keywords
endox
nucleic acid
polypeptide
amino acid
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002386199A
Other languages
English (en)
Inventor
Sudhirdas K. Prayaga
Richard A. Shimkets
Kumud Majumder
Andrew Eisen
Corine Vernet
Steven K. Spaderna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2386199A1 publication Critical patent/CA2386199A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne de nouvelles séquences d'acide nucléique d'origine humaine qui codent des polypeptides de type endozépine ; des polypeptides codés par ces séquences d'acide nucléique et des anticorps qui se lient de manière immunospécifique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments dudit polypeptide, dudit polynucléotide ou dudit anticorps. On décrit également des procédés de thérapie, de diagnostic et de recherche permettant de diagnostiquer, traiter et prévenir des maladies associées à ce nouvel acide nucléique de type endozépine et à la protéine d'origine humaine.
CA002386199A 1999-10-05 2000-10-05 Polypeptides de type endozepine et polynucleotides codant ces derniers Abandoned CA2386199A1 (fr)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US15778699P 1999-10-05 1999-10-05
US60/157,786 1999-10-05
US16416499P 1999-11-09 1999-11-09
US60/164,164 1999-11-09
US17450500P 2000-01-04 2000-01-04
US60/174,505 2000-01-04
US18385900P 2000-02-22 2000-02-22
US60/183,859 2000-02-22
US19074000P 2000-03-20 2000-03-20
US60/190,740 2000-03-20
US19113300P 2000-03-22 2000-03-22
US60/191,133 2000-03-22
US20600600P 2000-05-19 2000-05-19
US60/206,006 2000-05-19
US21568400P 2000-06-30 2000-06-30
US60/215,684 2000-06-30
US21949000P 2000-07-20 2000-07-20
US60/219,490 2000-07-20
US22707200P 2000-08-22 2000-08-22
US60/227,072 2000-08-22
US67946000A 2000-10-04 2000-10-04
US09/679,460 2000-10-04
PCT/US2000/041077 WO2001025436A2 (fr) 1999-10-05 2000-10-05 Polypeptides de type endozepine et polynucleotides codant ces derniers

Publications (1)

Publication Number Publication Date
CA2386199A1 true CA2386199A1 (fr) 2001-04-12

Family

ID=27582691

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002386199A Abandoned CA2386199A1 (fr) 1999-10-05 2000-10-05 Polypeptides de type endozepine et polynucleotides codant ces derniers

Country Status (4)

Country Link
EP (1) EP1222277A2 (fr)
JP (1) JP2003527831A (fr)
CA (1) CA2386199A1 (fr)
WO (1) WO2001025436A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001068840A2 (fr) * 2000-03-14 2001-09-20 Bayer Aktiengesellschaft REGULATION DE LA PROTEINE HUMAINE SEMBLABLE A ACYLE CoA/INHIBITEUR DE LIAISON DU DIAZEPAM
JP2005501528A (ja) * 2001-06-05 2005-01-20 エクセリクシス・インコーポレイテッド ｐ５３経路のモディファイヤーとしてのＧＦＡＴｓおよび使用方法
EP3684471A1 (fr) 2017-09-20 2020-07-29 Institut National de la Sante et de la Recherche Medicale (INSERM) Méthodes et compositions pharmaceutiques pour la modulation de l'autophagie
WO2020160183A1 (fr) * 2019-01-29 2020-08-06 Holobiome, Inc. Procédés et compositions pour traiter et prévenir des troubles du système nerveux central et d'autres états provoqués par une dysbiose microbienne intestinale
CN111254178A (zh) * 2020-03-23 2020-06-09 吉林大学 一种林蛙皮小分子肽螯合铁的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013089A1 (fr) * 1985-01-25 1993-07-08 Urban Frank J Acides carboxyliques de polyether macrocyclique
US5616311A (en) * 1991-01-15 1997-04-01 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
EP0862631A1 (fr) * 1995-10-26 1998-09-09 The Board Of Regents, The University Of Texas System Facteur luminal liberant la cholecystokinine
US5734038A (en) * 1996-08-16 1998-03-31 Incyte Pharmaceuticals, Inc. Human DBI/ACBP-like protein

Also Published As

Publication number Publication date
EP1222277A2 (fr) 2002-07-17
JP2003527831A (ja) 2003-09-24
WO2001025436A3 (fr) 2002-01-24
WO2001025436A2 (fr) 2001-04-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead