CA2386088A1 - Peptides antigeniques mage-a12 et utilisation - Google Patents
Peptides antigeniques mage-a12 et utilisation Download PDFInfo
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- CA2386088A1 CA2386088A1 CA002386088A CA2386088A CA2386088A1 CA 2386088 A1 CA2386088 A1 CA 2386088A1 CA 002386088 A CA002386088 A CA 002386088A CA 2386088 A CA2386088 A CA 2386088A CA 2386088 A1 CA2386088 A1 CA 2386088A1
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- peptides
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
L'invention concerne des peptides antigéniques dérivés de polypeptides MAGE-A12 et présentés par des molécules HLA. L'invention concerne également des procédés de diagnostic et de traitement faisant intervenir ces polypeptides.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16037499P | 1999-10-19 | 1999-10-19 | |
US60/160,374 | 1999-10-19 | ||
US17957000P | 2000-02-01 | 2000-02-01 | |
US60/179,570 | 2000-02-01 | ||
PCT/US2000/028852 WO2001029220A2 (fr) | 1999-10-19 | 2000-10-19 | Peptides antigeniques mage-a12 et utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2386088A1 true CA2386088A1 (fr) | 2001-04-26 |
Family
ID=26856840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002386088A Abandoned CA2386088A1 (fr) | 1999-10-19 | 2000-10-19 | Peptides antigeniques mage-a12 et utilisation |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1222274A2 (fr) |
JP (1) | JP2003512057A (fr) |
KR (1) | KR20020047249A (fr) |
CN (1) | CN1402782A (fr) |
AU (1) | AU1335601A (fr) |
CA (1) | CA2386088A1 (fr) |
HK (1) | HK1046925A1 (fr) |
WO (1) | WO2001029220A2 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001074847A2 (fr) * | 2000-03-30 | 2001-10-11 | The Government Of The United States Of America Represented By The Secretary, Department Of Health And Human Services | Epitope de lymphocyte t de mage-12 et acides nucleiques, vecteurs et cellules correspondants, compositions et procedes induisant une reaction immunitaire a un cancer |
DE60042687D1 (de) | 2000-09-15 | 2009-09-17 | Pasteur Institut | Proteinhaltigen Vektoren zur Einführung von Moleküle in CD11b exprimirende Zellen |
US20030148973A1 (en) * | 2001-05-23 | 2003-08-07 | Peter Emtage | MAGE-A1 peptides for treating or preventing cancer |
JP4781628B2 (ja) * | 2001-12-05 | 2011-09-28 | センス プロテオミック リミテッド | 対立遺伝子改変体のためのタンパク質アレイおよびその使用 |
GB0202018D0 (en) | 2002-01-29 | 2002-03-13 | Sense Proteomic Ltd | Tag and method |
ES2337694T3 (es) | 2003-11-21 | 2010-04-28 | Institut Pasteur | Toxina de adenilato ciclasa recombinante de bordetella que induce las respuestas de la celula t contra los antigenos tumorales. |
PT2113253E (pt) * | 2008-04-30 | 2010-06-15 | Immatics Biotechnologies Gmbh | Formulações novas de peptídeos associados a tumores que se ligam a moléculas de classe i ou ii do antígeno leucocitário humano (hla) para vacinas |
SI2755997T1 (sl) * | 2011-09-15 | 2018-11-30 | The United States of America, as represented by Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health | T-celični receptorji, ki prepoznajo HLA-A1- ali HLA-CW7-omejeni mage |
JP6077641B2 (ja) * | 2013-03-08 | 2017-02-08 | 大鵬薬品工業株式会社 | 新規ctlエピトープ5連結ペプチド |
PL3061771T3 (pl) | 2013-10-21 | 2020-10-19 | Taiho Pharmaceutical Co., Ltd. | Nowy peptyd o czterech połączonych epitopach dla ctl |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
GB9019812D0 (en) | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
US5487974A (en) | 1992-12-22 | 1996-01-30 | Ludwig Institute For Cancer-Research | Method for detecting complexes containing human leukocyte antigen A2 (HLA-A2) molecules and a tyrosinase drived peptide on abnormal cells |
CA2154468A1 (fr) | 1993-01-22 | 1994-08-04 | Pierre Van Der Bruggen | Methode pour identifier et traiter des individus portant des cellules cancereuses exprimant hla-c-clone 10/mage-1 |
US5620886A (en) | 1993-03-18 | 1997-04-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5571711A (en) | 1993-06-17 | 1996-11-05 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors |
US5610013A (en) | 1993-07-22 | 1997-03-11 | Ludwig Institute For Cancer Research | Method for diagnosing a disorder by determining expression of gage tumor rejection antigen precursors |
US5851523A (en) * | 1994-03-24 | 1998-12-22 | Ludwig Institute For Cancer Research. | Isolated, peptides derived from MAGE tumor rejection antigen precursors which complex with HLA-A2 molecules and uses thereof |
US6060257A (en) * | 1994-06-03 | 2000-05-09 | Ludwig Institute For Cancer Research | Tumor rejection antigens presented by HLA-B44 molecules, and uses thereof |
US5589334A (en) | 1994-06-03 | 1996-12-31 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecule which codes for a tumor rejection antigen precursor which is processed to an antigen presented by HLA-B44, and uses thereof |
US5830753A (en) | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
US5587289A (en) | 1995-03-14 | 1996-12-24 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which are members of the MAGE-Xp family and uses thereof |
US5965535A (en) * | 1997-09-12 | 1999-10-12 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
-
2000
- 2000-10-19 KR KR1020027004975A patent/KR20020047249A/ko not_active Application Discontinuation
- 2000-10-19 EP EP00975282A patent/EP1222274A2/fr not_active Withdrawn
- 2000-10-19 CN CN00814604A patent/CN1402782A/zh active Pending
- 2000-10-19 CA CA002386088A patent/CA2386088A1/fr not_active Abandoned
- 2000-10-19 AU AU13356/01A patent/AU1335601A/en not_active Abandoned
- 2000-10-19 JP JP2001532203A patent/JP2003512057A/ja active Pending
- 2000-10-19 WO PCT/US2000/028852 patent/WO2001029220A2/fr active Application Filing
-
2002
- 2002-09-27 HK HK02107155.4A patent/HK1046925A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU1335601A (en) | 2001-04-30 |
WO2001029220A3 (fr) | 2002-03-07 |
EP1222274A2 (fr) | 2002-07-17 |
WO2001029220A2 (fr) | 2001-04-26 |
JP2003512057A (ja) | 2003-04-02 |
KR20020047249A (ko) | 2002-06-21 |
HK1046925A1 (zh) | 2003-01-30 |
CN1402782A (zh) | 2003-03-12 |
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